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340 related items for PubMed ID: 17526734

  • 1. Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development.
    Terzian T, Wang Y, Van Pelt CS, Box NF, Travis EL, Lozano G.
    Mol Cell Biol; 2007 Aug; 27(15):5479-85. PubMed ID: 17526734
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  • 6. Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development.
    Eischen CM, Alt JR, Wang P.
    Oncogene; 2004 Nov 25; 23(55):8931-40. PubMed ID: 15467748
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  • 7. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
    Toledo F, Krummel KA, Lee CJ, Liu CW, Rodewald LW, Tang M, Wahl GM.
    Cancer Cell; 2006 Apr 25; 9(4):273-85. PubMed ID: 16616333
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  • 8. Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.
    Francoz S, Froment P, Bogaerts S, De Clercq S, Maetens M, Doumont G, Bellefroid E, Marine JC.
    Proc Natl Acad Sci U S A; 2006 Feb 28; 103(9):3232-7. PubMed ID: 16492744
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  • 9. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.
    Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G.
    Nat Genet; 2001 Sep 28; 29(1):92-5. PubMed ID: 11528400
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  • 10. The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.
    Joshi Y, Sória MG, Quadrato G, Inak G, Zhou L, Hervera A, Rathore KI, Elnaggar M, Cucchiarini M, Marine JC, Puttagunta R, Di Giovanni S.
    Brain; 2015 Jul 28; 138(Pt 7):1843-62. PubMed ID: 25981963
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  • 11. Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.
    Pant V, Xiong S, Iwakuma T, Quintás-Cardama A, Lozano G.
    Proc Natl Acad Sci U S A; 2011 Jul 19; 108(29):11995-2000. PubMed ID: 21730132
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  • 12. Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
    Iwakuma T, Parant JM, Fasulo M, Zwart E, Jacks T, de Vries A, Lozano G.
    Oncogene; 2004 Oct 07; 23(46):7644-50. PubMed ID: 15361844
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  • 13. Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development.
    Steinman HA, Hoover KM, Keeler ML, Sands AT, Jones SN.
    Oncogene; 2005 Nov 24; 24(53):7935-40. PubMed ID: 16027727
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  • 14. Distinct roles of Mdm2 and Mdm4 in red cell production.
    Maetens M, Doumont G, Clercq SD, Francoz S, Froment P, Bellefroid E, Klingmuller U, Lozano G, Marine JC.
    Blood; 2007 Mar 15; 109(6):2630-3. PubMed ID: 17105817
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  • 15. Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
    Chavez-Reyes A, Parant JM, Amelse LL, de Oca Luna RM, Korsmeyer SJ, Lozano G.
    Cancer Res; 2003 Dec 15; 63(24):8664-9. PubMed ID: 14695178
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  • 16. Synergistic regulation of p53 by Mdm2 and Mdm4 is critical in cardiac endocardial cushion morphogenesis during heart development.
    Zhang Q, He X, Chen L, Zhang C, Gao X, Yang Z, Liu G.
    J Pathol; 2012 Nov 15; 228(3):416-28. PubMed ID: 22821713
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  • 17. Mdm2 and Mdm4 loss regulates distinct p53 activities.
    Barboza JA, Iwakuma T, Terzian T, El-Naggar AK, Lozano G.
    Mol Cancer Res; 2008 Jun 15; 6(6):947-54. PubMed ID: 18567799
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  • 19. MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation.
    Qi DL, Cobrinik D.
    Oncogene; 2017 Mar 30; 36(13):1760-1769. PubMed ID: 27748758
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  • 20. Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.
    Giglio S, Mancini F, Pellegrino M, Di Conza G, Puxeddu E, Sacchi A, Pontecorvi A, Moretti F.
    Oncogene; 2010 Nov 04; 29(44):5935-45. PubMed ID: 20697359
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