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178 related items for PubMed ID: 17532483

  • 1. Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs.
    Narayanasamy J, Pullagurla MR, Sharon A, Wang J, Schinazi RF, Chu CK.
    Antiviral Res; 2007 Sep; 75(3):198-209. PubMed ID: 17532483
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  • 6. Phosphoramidate and phosphate prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine: synthesis, anti-HIV activity and stability studies.
    Liang Y, Narayanasamy J, Schinazi RF, Chu CK.
    Bioorg Med Chem; 2006 Apr 01; 14(7):2178-89. PubMed ID: 16314108
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  • 7. In vitro combination of amdoxovir and the inosine monophosphate dehydrogenase inhibitors mycophenolic acid and ribavirin demonstrates potent activity against wild-type and drug-resistant variants of human immunodeficiency virus type 1.
    Borroto-Esoda K, Myrick F, Feng J, Jeffrey J, Furman P.
    Antimicrob Agents Chemother; 2004 Nov 01; 48(11):4387-94. PubMed ID: 15504868
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  • 8. 5'-O-Aliphatic and amino acid ester prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine (DOT): synthesis, anti-HIV activity, cytotoxicity and stability studies.
    Liang Y, Sharon A, Grier JP, Rapp KL, Schinazi RF, Chu CK.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1404-9. PubMed ID: 19153047
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  • 9. Anti-HIV-1 activities of 1,3-dioxolane guanine and 2,6-diaminopurine dioxolane.
    Gu Z, Wainberg MA, Nguyen-Ba P, L'Heureux L, de Muys JM, Rando RF.
    Nucleosides Nucleotides; 1999 Feb 01; 18(4-5):891-2. PubMed ID: 10432704
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  • 10. Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach.
    Chong Y, Borroto-Esoda K, Furman PA, Schinazi RF, Chu CK.
    Antivir Chem Chemother; 2002 Mar 01; 13(2):115-28. PubMed ID: 12238529
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  • 11. PAMAM dendrimers and branched polyethyleneglycol (nanoparticles) prodrugs of (-)-beta-D-(2R, 4R)-dioxolane-thymine (DOT) and their anti-HIV activity.
    Liang Y, Narayanasamy J, Rapp KL, Schinazi RF, Chu CK.
    Antivir Chem Chemother; 2006 Mar 01; 17(6):321-9. PubMed ID: 17249246
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  • 12. Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5'-phosphates by mammalian phosphotransferases.
    Feng JY, Parker WB, Krajewski ML, Deville-Bonne D, Veron M, Krishnan P, Cheng YC, Borroto-Esoda K.
    Biochem Pharmacol; 2004 Nov 01; 68(9):1879-88. PubMed ID: 15450953
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  • 13. High-performance liquid chromatographic determination of (-)-beta-D-2,6-diaminopurine dioxolane and its metabolite, dioxolane guanosine, using ultraviolet and on-line radiochemical detection.
    Rajagopalan P, Gao Z, Chu CK, Schinazi RF, McClure HM, Boudinot FD.
    J Chromatogr B Biomed Appl; 1995 Oct 06; 672(1):119-24. PubMed ID: 8590923
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  • 14. Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients.
    Kewn S, Wang LH, Hoggard PG, Rousseau F, Hart R, MacNeela JP, Khoo SH, Back DJ.
    Antimicrob Agents Chemother; 2003 Jan 06; 47(1):255-61. PubMed ID: 12499199
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  • 15. Phosphoramidate prodrugs of (-)-β-D-(2R,4R)-dioxolane-thymine (DOT) as potent anti-HIV agents.
    Wang P, Rachakonda S, Zennou V, Keilman M, Niu C, Bao D, Ross BS, Furman PA, Otto MJ, Sofia MJ.
    Antivir Chem Chemother; 2012 May 14; 22(5):217-38. PubMed ID: 22358223
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  • 17. DAPD (Emory University/Triangle Pharmaceuticals/Abbott Laboratories).
    Corbett AH, Rublein JC.
    Curr Opin Investig Drugs; 2001 Mar 14; 2(3):348-53. PubMed ID: 11575703
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  • 20. Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
    Jeffrey JL, Feng JY, Qi CC, Anderson KS, Furman PA.
    J Biol Chem; 2003 May 23; 278(21):18971-9. PubMed ID: 12651859
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