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236 related items for PubMed ID: 17545685

  • 1. Human MD-2 discrimination of meningococcal lipid A structures and activation of TLR4.
    Zimmer SM, Zughaier SM, Tzeng YL, Stephens DS.
    Glycobiology; 2007 Aug; 17(8):847-56. PubMed ID: 17545685
    [Abstract] [Full Text] [Related]

  • 2. Hexa-acylation and KDO(2)-glycosylation determine the specific immunostimulatory activity of Neisseria meningitidis lipid A for human monocyte derived dendritic cells.
    Zughaier S, Agrawal S, Stephens DS, Pulendran B.
    Vaccine; 2006 Feb 27; 24(9):1291-7. PubMed ID: 16246469
    [Abstract] [Full Text] [Related]

  • 3. Neisseria meningitidis lipooligosaccharide structure-dependent activation of the macrophage CD14/Toll-like receptor 4 pathway.
    Zughaier SM, Tzeng YL, Zimmer SM, Datta A, Carlson RW, Stephens DS.
    Infect Immun; 2004 Jan 27; 72(1):371-80. PubMed ID: 14688118
    [Abstract] [Full Text] [Related]

  • 4. Stable transduction of bovine TLR4 and bovine MD-2 into LPS-nonresponsive cells and soluble CD14 promote the ability to respond to LPS.
    Sauter KS, Brcic M, Franchini M, Jungi TW.
    Vet Immunol Immunopathol; 2007 Jul 15; 118(1-2):92-104. PubMed ID: 17559944
    [Abstract] [Full Text] [Related]

  • 5. Monomeric endotoxin:protein complexes are essential for TLR4-dependent cell activation.
    Gioannini TL, Teghanemt A, Zhang D, Levis EN, Weiss JP.
    J Endotoxin Res; 2005 Jul 15; 11(2):117-23. PubMed ID: 15949139
    [Abstract] [Full Text] [Related]

  • 6. Preparation and characterization of truncated human lipopolysaccharide-binding protein in Escherichia coli.
    Kohara J, Tsuneyoshi N, Gauchat JF, Kimoto M, Fukudome K.
    Protein Expr Purif; 2006 Oct 15; 49(2):276-83. PubMed ID: 16839777
    [Abstract] [Full Text] [Related]

  • 7. Penta-acylated lipopolisaccharide binds to murine MD-2 but does not induce the oligomerization of TLR4 required for signal transduction.
    Tsuneyoshi N, Kohara J, Bahrun U, Saitoh S, Akashi S, Gauchat JF, Kimoto M, Fukudome K.
    Cell Immunol; 2006 Nov 15; 244(1):57-64. PubMed ID: 17420011
    [Abstract] [Full Text] [Related]

  • 8. Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization.
    Saitoh S, Akashi S, Yamada T, Tanimura N, Kobayashi M, Konno K, Matsumoto F, Fukase K, Kusumoto S, Nagai Y, Kusumoto Y, Kosugi A, Miyake K.
    Int Immunol; 2004 Jul 15; 16(7):961-9. PubMed ID: 15184344
    [Abstract] [Full Text] [Related]

  • 9. Human Toll-like receptor 4 recognizes host-specific LPS modifications.
    Hajjar AM, Ernst RK, Tsai JH, Wilson CB, Miller SI.
    Nat Immunol; 2002 Apr 15; 3(4):354-9. PubMed ID: 11912497
    [Abstract] [Full Text] [Related]

  • 10. Regulation of interactions of endotoxin with host cells.
    Gioannini TL, Teghanemt A, Zarember KA, Weiss JP.
    J Endotoxin Res; 2003 Apr 15; 9(6):401-8. PubMed ID: 14733729
    [Abstract] [Full Text] [Related]

  • 11. Neisseria meningitidis type C capsular polysaccharide inhibits lipooligosaccharide-induced cell activation by binding to CD14.
    Kocabas C, Katsenelson N, Kanswal S, Kennedy MN, Cui X, Blake MS, Segal DM, Akkoyunlu M.
    Cell Microbiol; 2007 May 15; 9(5):1297-310. PubMed ID: 17250593
    [Abstract] [Full Text] [Related]

  • 12. Activation of human meningeal cells is modulated by lipopolysaccharide (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling.
    Humphries HE, Triantafilou M, Makepeace BL, Heckels JE, Triantafilou K, Christodoulides M.
    Cell Microbiol; 2005 Mar 15; 7(3):415-30. PubMed ID: 15679844
    [Abstract] [Full Text] [Related]

  • 13. MD-2 binds to bacterial lipopolysaccharide.
    Viriyakosol S, Kirkland T, Soldau K, Tobias P.
    J Endotoxin Res; 2000 Mar 15; 6(6):489-91. PubMed ID: 11521076
    [Abstract] [Full Text] [Related]

  • 14. TLR4-dependent adjuvant activity of Neisseria meningitidis lipid A.
    Zughaier S, Steeghs L, van der Ley P, Stephens DS.
    Vaccine; 2007 May 30; 25(22):4401-9. PubMed ID: 17466419
    [Abstract] [Full Text] [Related]

  • 15. Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production.
    Sprong T, Ley Pv, Abdollahi-Roodsaz S, Joosten L, Meer Jv, Netea M, Deuren Mv.
    Innate Immun; 2011 Dec 30; 17(6):517-25. PubMed ID: 21088052
    [Abstract] [Full Text] [Related]

  • 16. Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran.
    Kim HM, Park BS, Kim JI, Kim SE, Lee J, Oh SC, Enkhbayar P, Matsushima N, Lee H, Yoo OJ, Lee JO.
    Cell; 2007 Sep 07; 130(5):906-17. PubMed ID: 17803912
    [Abstract] [Full Text] [Related]

  • 17. [Analysis of Toll-like receptor 4 and myeloid differentiation protein-2 interaction with fluorescence resonance energy transfer].
    Liu YW, Liu JH, Tang J, Zhao Q, Li JJ, Zhao MZ, Li ZJ, Wang GJ, Zhong TY, Deng P, Jiang Y.
    Nan Fang Yi Ke Da Xue Xue Bao; 2006 Aug 07; 26(8):1101-5. PubMed ID: 16939893
    [Abstract] [Full Text] [Related]

  • 18. Mechanism regulating cell surface expression and activation of Toll-like receptor 4.
    Saitoh S, Miyake K.
    Chem Rec; 2006 Aug 07; 6(6):311-9. PubMed ID: 17304555
    [Abstract] [Full Text] [Related]

  • 19. Bordetella pertussis Lipid A Recognition by Toll-like Receptor 4 and MD-2 Is Dependent on Distinct Charged and Uncharged Interfaces.
    Maeshima N, Evans-Atkinson T, Hajjar AM, Fernandez RC.
    J Biol Chem; 2015 May 22; 290(21):13440-53. PubMed ID: 25837248
    [Abstract] [Full Text] [Related]

  • 20. Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
    Ohto U, Fukase K, Miyake K, Satow Y.
    Science; 2007 Jun 15; 316(5831):1632-4. PubMed ID: 17569869
    [Abstract] [Full Text] [Related]

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