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790 related items for PubMed ID: 17550976

  • 1. Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.
    Neilson LM, Zhu J, Xie J, Malabarba MG, Sakamoto K, Wagner KU, Kirken RA, Rui H.
    Mol Endocrinol; 2007 Sep; 21(9):2218-32. PubMed ID: 17550976
    [Abstract] [Full Text] [Related]

  • 2. Janus kinase 2 (JAK2) regulates prolactin-mediated chloride transport in mouse mammary epithelial cells through tyrosine phosphorylation of Na+-K+-2Cl- cotransporter.
    Selvaraj NG, Omi E, Gibori G, Rao MC.
    Mol Endocrinol; 2000 Dec; 14(12):2054-65. PubMed ID: 11117534
    [Abstract] [Full Text] [Related]

  • 3. Prolactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer Cells.
    Pedraz-Cuesta E, Fredsted J, Jensen HH, Bornebusch A, Nejsum LN, Kragelund BB, Pedersen SF.
    Mol Endocrinol; 2016 Jul; 30(7):693-708. PubMed ID: 27176613
    [Abstract] [Full Text] [Related]

  • 4. PRL-induced ERalpha gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase.
    Frasor J, Barkai U, Zhong L, Fazleabas AT, Gibori G.
    Mol Endocrinol; 2001 Nov; 15(11):1941-52. PubMed ID: 11682625
    [Abstract] [Full Text] [Related]

  • 5. Ethanol inhibits prolactin-induced activation of the JAK/STAT pathway in cultured astrocytes.
    DeVito WJ, Stone S.
    J Cell Biochem; 1999 Aug 01; 74(2):278-91. PubMed ID: 10404396
    [Abstract] [Full Text] [Related]

  • 6. JAK2 and STAT5, but not JAK1 and STAT1, are required for prolactin-induced beta-lactoglobulin transcription.
    Han Y, Watling D, Rogers NC, Stark GR.
    Mol Endocrinol; 1997 Jul 01; 11(8):1180-8. PubMed ID: 9212064
    [Abstract] [Full Text] [Related]

  • 7. Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition.
    Sultan AS, Brim H, Sherif ZA.
    Cancer Sci; 2008 Feb 01; 99(2):272-9. PubMed ID: 18271926
    [Abstract] [Full Text] [Related]

  • 8. Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells.
    Proietti C, Salatino M, Rosemblit C, Carnevale R, Pecci A, Kornblihtt AR, Molinolo AA, Frahm I, Charreau EH, Schillaci R, Elizalde PV.
    Mol Cell Biol; 2005 Jun 01; 25(12):4826-40. PubMed ID: 15923602
    [Abstract] [Full Text] [Related]

  • 9. A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling.
    García-Martínez JM, Calcabrini A, González L, Martín-Forero E, Agulló-Ortuño MT, Simon V, Watkin H, Anderson SM, Roche S, Martín-Pérez J.
    Cell Signal; 2010 Mar 01; 22(3):415-26. PubMed ID: 19892015
    [Abstract] [Full Text] [Related]

  • 10. Dominant negative variants of the SHP-2 tyrosine phosphatase inhibit prolactin activation of Jak2 (janus kinase 2) and induction of Stat5 (signal transducer and activator of transcription 5)-dependent transcription.
    Berchtold S, Volarevic S, Moriggl R, Mercep M, Groner B.
    Mol Endocrinol; 1998 Apr 01; 12(4):556-67. PubMed ID: 9544991
    [Abstract] [Full Text] [Related]

  • 11. Convergence of signaling transduced by prolactin (PRL)/cytokine chimeric receptors on PRL-responsive gene transcription.
    Ferrag F, Chiarenza A, Goffin V, Kelly PA.
    Mol Endocrinol; 1996 Apr 01; 10(4):451-60. PubMed ID: 8721989
    [Abstract] [Full Text] [Related]

  • 12. JAK kinases overexpression promotes in vitro cell transformation.
    Knoops L, Hornakova T, Royer Y, Constantinescu SN, Renauld JC.
    Oncogene; 2008 Mar 06; 27(11):1511-9. PubMed ID: 17873904
    [Abstract] [Full Text] [Related]

  • 13. The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells.
    Linher-Melville K, Singh G.
    BMC Cancer; 2014 Jun 09; 14():415. PubMed ID: 24913037
    [Abstract] [Full Text] [Related]

  • 14. Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells.
    Huang Y, Li X, Jiang J, Frank SJ.
    Oncogene; 2006 Dec 07; 25(58):7565-76. PubMed ID: 16785991
    [Abstract] [Full Text] [Related]

  • 15. EGF-induced MMP-9 expression is mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line.
    Kim S, Choi JH, Lim HI, Lee SK, Kim WW, Cho S, Kim JS, Kim JH, Choe JH, Nam SJ, Lee JE, Yang JH.
    Cell Signal; 2009 Jun 07; 21(6):892-8. PubMed ID: 19385051
    [Abstract] [Full Text] [Related]

  • 16. Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.
    Neradugomma NK, Subramaniam D, Tawfik OW, Goffin V, Kumar TR, Jensen RA, Anant S.
    Carcinogenesis; 2014 Apr 07; 35(4):795-806. PubMed ID: 24265293
    [Abstract] [Full Text] [Related]

  • 17. Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells.
    Nouhi Z, Chughtai N, Hartley S, Cocolakis E, Lebrun JJ, Ali S.
    Cancer Res; 2006 Feb 01; 66(3):1824-32. PubMed ID: 16452244
    [Abstract] [Full Text] [Related]

  • 18. Cytokine-inducible SH2-containing protein suppresses PRL signaling by binding the PRL receptor.
    Dif F, Saunier E, Demeneix B, Kelly PA, Edery M.
    Endocrinology; 2001 Dec 01; 142(12):5286-93. PubMed ID: 11713228
    [Abstract] [Full Text] [Related]

  • 19. Expression of functional prolactin receptors in nonpregnant human endometrium: janus kinase-2, signal transducer and activator of transcription-1 (STAT1), and STAT5 proteins are phosphorylated after stimulation with prolactin.
    Jabbour HN, Critchley HO, Boddy SC.
    J Clin Endocrinol Metab; 1998 Jul 01; 83(7):2545-53. PubMed ID: 9661641
    [Abstract] [Full Text] [Related]

  • 20. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M.
    Oncogene; 2000 Sep 28; 19(41):4795-801. PubMed ID: 11032030
    [Abstract] [Full Text] [Related]

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