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Journal Abstract Search

136 related items for PubMed ID: 17559192

  • 1. Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1).
    Sakurai A, Onishi Y, Hirano H, Seigneuret M, Obanayama K, Kim G, Liew EL, Sakaeda T, Yoshiura K, Niikawa N, Sakurai M, Ishikawa T.
    Biochemistry; 2007 Jul 03; 46(26):7678-93. PubMed ID: 17559192
    [Abstract] [Full Text] [Related]

  • 2. Emerging new technologies in Pharmacogenomics: rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1).
    Ishikawa T, Sakurai A, Hirano H, Lezhava A, Sakurai M, Hayashizaki Y.
    Pharmacol Ther; 2010 Apr 03; 126(1):69-81. PubMed ID: 20138191
    [Abstract] [Full Text] [Related]

  • 3. In-vitro transport characteristics discriminate wild-type ABCB1 (MDR1) from ALA893SER and ALA893THR polymorphisms.
    Schaefer M, Roots I, Gerloff T.
    Pharmacogenet Genomics; 2006 Dec 03; 16(12):855-61. PubMed ID: 17108809
    [Abstract] [Full Text] [Related]

  • 4. Common germline MDR1/ABCB1 functional polymorphisms and haplotypes modify susceptibility to colorectal cancers with high microsatellite instability.
    Potocnik U, Glavac D, Dean M.
    Cancer Genet Cytogenet; 2008 May 03; 183(1):28-34. PubMed ID: 18474294
    [Abstract] [Full Text] [Related]

  • 5. Mutational analysis of the P-glycoprotein first intracellular loop and flanking transmembrane domains.
    Kwan T, Gros P.
    Biochemistry; 1998 Mar 10; 37(10):3337-50. PubMed ID: 9521654
    [Abstract] [Full Text] [Related]

  • 6. Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket.
    Loo TW, Bartlett MC, Clarke DM.
    Biochem J; 2006 Oct 15; 399(2):351-9. PubMed ID: 16813563
    [Abstract] [Full Text] [Related]

  • 7. Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs.
    Hung CC, Chen CC, Lin CJ, Liou HH.
    Pharmacogenet Genomics; 2008 May 15; 18(5):390-402. PubMed ID: 18408562
    [Abstract] [Full Text] [Related]

  • 8. Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta.
    Rahi M, Heikkinen T, Hakkola J, Hakala K, Wallerman O, Wadelius M, Wadelius C, Laine K.
    Hum Exp Toxicol; 2008 Jan 15; 27(1):65-71. PubMed ID: 18480151
    [Abstract] [Full Text] [Related]

  • 9. Genetic polymorphisms in the ABCB1 gene and the effects of fentanyl in Koreans.
    Park HJ, Shinn HK, Ryu SH, Lee HS, Park CS, Kang JH.
    Clin Pharmacol Ther; 2007 Apr 15; 81(4):539-46. PubMed ID: 17192767
    [Abstract] [Full Text] [Related]

  • 10. First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line.
    Zaja R, Lončar J, Popovic M, Smital T.
    Aquat Toxicol; 2011 May 15; 103(1-2):53-62. PubMed ID: 21392495
    [Abstract] [Full Text] [Related]

  • 11. Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients.
    Mosyagin I, Runge U, Schroeder HW, Dazert E, Vogelgesang S, Siegmund W, Warzok RW, Cascorbi I.
    Epilepsia; 2008 Sep 15; 49(9):1555-61. PubMed ID: 18494787
    [Abstract] [Full Text] [Related]

  • 12. Haplotypic structure of ABCB1/MDR1 gene modifies the risk of the acute allograft rejection in renal transplant recipients.
    Bandur S, Petrasek J, Hribova P, Novotna E, Brabcova I, Viklicky O.
    Transplantation; 2008 Nov 15; 86(9):1206-13. PubMed ID: 19005401
    [Abstract] [Full Text] [Related]

  • 13. Determination of ABCB1 polymorphisms and haplotypes frequencies in a French population.
    Jeannesson E, Albertini L, Siest G, Gomes AM, Ribeiro V, Aslanidis C, Schmitz G, Visvikis-Siest S.
    Fundam Clin Pharmacol; 2007 Aug 15; 21(4):411-8. PubMed ID: 17635180
    [Abstract] [Full Text] [Related]

  • 14. Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients.
    Vaclavikova R, Nordgard SH, Alnaes GI, Hubackova M, Kubala E, Kodet R, Mrhalova M, Novotny J, Gut I, Kristensen VN, Soucek P.
    Pharmacogenet Genomics; 2008 Mar 15; 18(3):263-73. PubMed ID: 18300948
    [Abstract] [Full Text] [Related]

  • 15. Promoter polymorphisms and allelic imbalance in ABCB1 expression.
    Loeuillet C, Weale M, Deutsch S, Rotger M, Soranzo N, Wyniger J, Lettre G, Dupré Y, Thuillard D, Beckmann JS, Antonarakis SE, Goldstein DB, Telenti A.
    Pharmacogenet Genomics; 2007 Nov 15; 17(11):951-9. PubMed ID: 18075465
    [Abstract] [Full Text] [Related]

  • 16. Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance.
    Marzolini C, Paus E, Buclin T, Kim RB.
    Clin Pharmacol Ther; 2004 Jan 15; 75(1):13-33. PubMed ID: 14749689
    [Abstract] [Full Text] [Related]

  • 17. Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.
    Murayama N, Soyama A, Saito Y, Nakajima Y, Komamura K, Ueno K, Kamakura S, Kitakaze M, Kimura H, Goto Y, Saitoh O, Katoh M, Ohnuma T, Kawai M, Sugai K, Ohtsuki T, Suzuki C, Minami N, Ozawa S, Sawada J.
    J Pharmacol Exp Ther; 2004 Jan 15; 308(1):300-6. PubMed ID: 14563787
    [Abstract] [Full Text] [Related]

  • 18. MDR1 gene polymorphisms and clinical relevance.
    Li YH, Wang YH, Li Y, Yang L.
    Yi Chuan Xue Bao; 2006 Feb 15; 33(2):93-104. PubMed ID: 16529292
    [Abstract] [Full Text] [Related]

  • 19. Potential impact of ABCB1 (p-glycoprotein) polymorphisms on avermectin toxicity in humans.
    Macdonald N, Gledhill A.
    Arch Toxicol; 2007 Aug 15; 81(8):553-63. PubMed ID: 17354009
    [Abstract] [Full Text] [Related]

  • 20. P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.
    Cascorbi I.
    Handb Exp Pharmacol; 2011 Aug 15; (201):261-83. PubMed ID: 21103972
    [Abstract] [Full Text] [Related]

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