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606 related items for PubMed ID: 17560642

  • 1. The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target.
    Fishel ML, Kelley MR.
    Mol Aspects Med; 2007; 28(3-4):375-95. PubMed ID: 17560642
    [Abstract] [Full Text] [Related]

  • 2. Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer.
    Kelley MR, Cheng L, Foster R, Tritt R, Jiang J, Broshears J, Koch M.
    Clin Cancer Res; 2001 Apr; 7(4):824-30. PubMed ID: 11309329
    [Abstract] [Full Text] [Related]

  • 3. Anticancer clinical utility of the apurinic/apyrimidinic endonuclease/redox factor-1 (APE/Ref-1).
    Zhang Y, Wang J.
    Chin J Cancer; 2010 Mar; 29(3):333-9. PubMed ID: 20193121
    [Abstract] [Full Text] [Related]

  • 4. Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.
    Robertson KA, Bullock HA, Xu Y, Tritt R, Zimmerman E, Ulbright TM, Foster RS, Einhorn LH, Kelley MR.
    Cancer Res; 2001 Mar 01; 61(5):2220-5. PubMed ID: 11280790
    [Abstract] [Full Text] [Related]

  • 5. Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1).
    Laev SS, Salakhutdinov NF, Lavrik OI.
    Bioorg Med Chem; 2017 May 01; 25(9):2531-2544. PubMed ID: 28161249
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M, Kelley MR.
    Anticancer Res; 2004 May 01; 24(4):2127-34. PubMed ID: 15330152
    [Abstract] [Full Text] [Related]

  • 7. APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions.
    Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK.
    Exp Mol Med; 2014 Jul 18; 46(7):e106. PubMed ID: 25033834
    [Abstract] [Full Text] [Related]

  • 8. Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction.
    Mantha AK, Dhiman M, Taglialatela G, Perez-Polo RJ, Mitra S.
    J Neurosci Res; 2012 Jun 18; 90(6):1230-9. PubMed ID: 22488727
    [Abstract] [Full Text] [Related]

  • 9. APE1/Ref-1 enhances DNA binding activity of mutant p53 in a redox-dependent manner.
    Cun Y, Dai N, Li M, Xiong C, Zhang Q, Sui J, Qian C, Wang D.
    Oncol Rep; 2014 Feb 18; 31(2):901-9. PubMed ID: 24297337
    [Abstract] [Full Text] [Related]

  • 10. Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1.
    Luo M, Delaplane S, Jiang A, Reed A, He Y, Fishel M, Nyland RL, Borch RF, Qiao X, Georgiadis MM, Kelley MR.
    Antioxid Redox Signal; 2008 Nov 18; 10(11):1853-67. PubMed ID: 18627350
    [Abstract] [Full Text] [Related]

  • 11. Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1.
    Kelley MR, Parsons SH.
    Antioxid Redox Signal; 2001 Aug 18; 3(4):671-83. PubMed ID: 11554453
    [Abstract] [Full Text] [Related]

  • 12. Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer.
    Singh-Gupta V, Joiner MC, Runyan L, Yunker CK, Sarkar FH, Miller S, Gadgeel SM, Konski AA, Hillman GG.
    J Thorac Oncol; 2011 Apr 18; 6(4):688-98. PubMed ID: 21325978
    [Abstract] [Full Text] [Related]

  • 13. DNA repair and redox activities and inhibitors of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): a comparative analysis and their scope and limitations toward anticancer drug development.
    Kaur G, Cholia RP, Mantha AK, Kumar R.
    J Med Chem; 2014 Dec 26; 57(24):10241-56. PubMed ID: 25280182
    [Abstract] [Full Text] [Related]

  • 14. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE1/Ref-1) in human ovarian cancer and indentification of the therapeutic potential of APE1/Ref-1 inhibitor.
    Zhang Y, Wang J, Xiang D, Wang D, Xin X.
    Int J Oncol; 2009 Nov 26; 35(5):1069-79. PubMed ID: 19787261
    [Abstract] [Full Text] [Related]

  • 15. The intracellular localization of APE1/Ref-1: more than a passive phenomenon?
    Tell G, Damante G, Caldwell D, Kelley MR.
    Antioxid Redox Signal; 2005 Nov 26; 7(3-4):367-84. PubMed ID: 15706084
    [Abstract] [Full Text] [Related]

  • 16. Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1.
    Li M, Vascotto C, Xu S, Dai N, Qing Y, Zhong Z, Tell G, Wang D.
    Free Radic Biol Med; 2012 Jul 15; 53(2):237-48. PubMed ID: 22580151
    [Abstract] [Full Text] [Related]

  • 17. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.
    Fishel ML, Jiang Y, Rajeshkumar NV, Scandura G, Sinn AL, He Y, Shen C, Jones DR, Pollok KE, Ivan M, Maitra A, Kelley MR.
    Mol Cancer Ther; 2011 Sep 15; 10(9):1698-708. PubMed ID: 21700832
    [Abstract] [Full Text] [Related]

  • 18. Going APE over ref-1.
    Evans AR, Limp-Foster M, Kelley MR.
    Mutat Res; 2000 Oct 16; 461(2):83-108. PubMed ID: 11018583
    [Abstract] [Full Text] [Related]

  • 19. Probing conformational changes in Ape1 during the progression of base excision repair.
    Yu E, Gaucher SP, Hadi MZ.
    Biochemistry; 2010 May 11; 49(18):3786-96. PubMed ID: 20377204
    [Abstract] [Full Text] [Related]

  • 20. Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.
    Unnikrishnan A, Raffoul JJ, Patel HV, Prychitko TM, Anyangwe N, Meira LB, Friedberg EC, Cabelof DC, Heydari AR.
    Free Radic Biol Med; 2009 Jun 01; 46(11):1488-99. PubMed ID: 19268524
    [Abstract] [Full Text] [Related]

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