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70 related items for PubMed ID: 17562437

  • 1. Simultaneous alteration of de novo and salvage pathway to the deoxynucleoside triphosphate pool by (E)-2'-deoxy-(fluoromethylene)cytidine (FMdC) and zidovudine (AZT) results in increased radiosensitivity in vitro.
    Coucke PA, Cottin E, Decosterd LA.
    Acta Oncol; 2007; 46(5):612-20. PubMed ID: 17562437
    [Abstract] [Full Text] [Related]

  • 2. The ribonucleoside diphosphate reductase inhibitor (E)-2'-deoxy-(fluoromethylene)cytidine as a cytotoxic radiosensitizer in vitro.
    Coucke PA, Decosterd LA, Li YX, Cottin E, Chen X, Sun LQ, Stern S, Paschoud N, Denekamp J.
    Cancer Res; 1999 Oct 15; 59(20):5219-26. PubMed ID: 10537300
    [Abstract] [Full Text] [Related]

  • 3. Positive interactive radiosensitisation in vitro with the combination of two nucleoside analogues, (E)-2'-deoxy-2'-(fluoromethylene) cytidine and iododeoxyuridine.
    Coucke PA, Cottin E, Azria D, Martineau P, Adamer F, Decosterd LA, Buchegger F, Do HP.
    Eur J Cancer; 2004 Jul 15; 40(10):1572-80. PubMed ID: 15196542
    [Abstract] [Full Text] [Related]

  • 4. (E)-2'-deoxy-2'-(fluoromethylene) cytidine potentiates radioresponse of two human solid tumor xenografts.
    Sun LQ, Li YX, Guillou L, Coucke PA.
    Cancer Res; 1998 Dec 01; 58(23):5411-7. PubMed ID: 9850073
    [Abstract] [Full Text] [Related]

  • 5. Antitumor and radiosensitizing effects of (E)-2'-deoxy-2'-(fluoromethylene) cytidine, a novel inhibitor of ribonucleoside diphosphate reductase, on human colon carcinoma xenografts in nude mice.
    Sun LQ, Li YX, Guillou L, Mirimanoff RO, Coucke PA.
    Cancer Res; 1997 Sep 15; 57(18):4023-8. PubMed ID: 9307288
    [Abstract] [Full Text] [Related]

  • 6. Potentiation of cytotoxicity and radiosensitization of (E)-2-deoxy-2'-(fluoromethylene) cytidine by pentoxifylline in vitro.
    Li YX, Sun LQ, Weber-Johnson K, Paschoud N, Coucke PA.
    Int J Cancer; 1999 Jan 05; 80(1):155-60. PubMed ID: 9935246
    [Abstract] [Full Text] [Related]

  • 7. Effect of 2'-deoxy-2'-(fluoromethylene) cytidine on the ultraviolet and X-ray sensitivity of HeLa cells.
    Snyder RD.
    Oncol Res; 1994 Jan 05; 6(4-5):177-82. PubMed ID: 7841540
    [Abstract] [Full Text] [Related]

  • 8. Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
    Morris GW, Iams TA, Slepchenko KG, McKee EE.
    Biochem J; 2009 Aug 27; 422(3):513-20. PubMed ID: 19558366
    [Abstract] [Full Text] [Related]

  • 9. 2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine.
    Törnevik Y, Eriksson S.
    Mol Pharmacol; 1990 Aug 27; 38(2):237-43. PubMed ID: 2166904
    [Abstract] [Full Text] [Related]

  • 10. Action of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on DNA metabolism: incorporation, excision, and cellular response.
    Zhou Y, Achanta G, Pelicano H, Gandhi V, Plunkett W, Huang P.
    Mol Pharmacol; 2002 Jan 27; 61(1):222-9. PubMed ID: 11752224
    [Abstract] [Full Text] [Related]

  • 11. Cytostatic and cytotoxic effects of (E)-2'-deoxy-2'-(fluoromethylene)-cytidine on a solid tumor and a leukemia cell line.
    Grie P, Koronkiewicz M, Skierski JS.
    Acta Biochim Pol; 2000 Jan 27; 47(1):165-71. PubMed ID: 10961690
    [Abstract] [Full Text] [Related]

  • 12. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP, Nandy P, Avramis VI.
    In Vivo; 2000 Jan 27; 14(3):377-88. PubMed ID: 10904870
    [Abstract] [Full Text] [Related]

  • 13. Effect of FMdC on the cell cycle of some leukemia cell lines.
    Skierski JS, Koronkiewicz M, Grieb P.
    Cytometry; 1999 Dec 01; 37(4):302-7. PubMed ID: 10547615
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on the 9L rat brain tumor model using MRI.
    Ross BD, Chenevert TL, Garwood M, Kim B, Stegman LD, Ben-Yoseph O, Zwolshen J, Rehemtulla A, Sunkara PS.
    NMR Biomed; 2003 Apr 01; 16(2):67-76. PubMed ID: 12730947
    [Abstract] [Full Text] [Related]

  • 15. Azidothymidine (AZT) as a potential modifier of radiation response in vitro.
    Copaceanu ML, Coucke PA, Cottin E, Paschoud N, Mirimanoff RO.
    Acta Oncol; 1995 Apr 01; 34(2):213-8. PubMed ID: 7718259
    [Abstract] [Full Text] [Related]

  • 16. The effect of recombinant human granulocyte-macrophage colony-stimulating factor (rGM-CSF) on 3'-azido-3'-deoxythymidine (AZT)-mediated biochemical and cytotoxic effects on normal human myeloid progenitor cells.
    Bhalla K, Birkhofer M, Grant S, Graham G.
    Exp Hematol; 1989 Jan 01; 17(1):17-20. PubMed ID: 2783247
    [Abstract] [Full Text] [Related]

  • 17. Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3'-azido-3'-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM).
    Fridland A, Connelly MC, Ashmun R.
    Mol Pharmacol; 1990 May 01; 37(5):665-70. PubMed ID: 2338944
    [Abstract] [Full Text] [Related]

  • 18. Metabolism of 2',2'-difluoro-2'-deoxycytidine and radiation sensitization of human colon carcinoma cells.
    Shewach DS, Hahn TM, Chang E, Hertel LW, Lawrence TS.
    Cancer Res; 1994 Jun 15; 54(12):3218-23. PubMed ID: 8205542
    [Abstract] [Full Text] [Related]

  • 19. Effect of AZT on thymidine phosphorylation in cultured H9c2, U-937, and Raji cell lines.
    Lynx MD, Kang BK, McKee EE.
    Biochem Pharmacol; 2008 Apr 15; 75(8):1610-5. PubMed ID: 18295188
    [Abstract] [Full Text] [Related]

  • 20. Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells.
    Frick LW, Nelson DJ, St Clair MH, Furman PA, Krenitsky TA.
    Biochem Biophys Res Commun; 1988 Jul 15; 154(1):124-9. PubMed ID: 3164996
    [Abstract] [Full Text] [Related]

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