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Journal Abstract Search

96 related items for PubMed ID: 17562805

  • 1. Pharmacokinetics of the antiviral agent beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine in rhesus monkeys.
    Asif G, Hurwitz SJ, Shi J, Hernandez-Santiago BI, Schinazi RF.
    Antimicrob Agents Chemother; 2007 Aug; 51(8):2877-82. PubMed ID: 17562805
    [Abstract] [Full Text] [Related]

  • 2. Monoval-LdC: efficient prodrug of 2'-deoxy-beta-L-cytidine (L-dC), a potent and selective anti-HBV agent.
    Benzaria S, Pierra C, Bardiot D, Cretton-Scott E, Bridges EG, Zhou XJ, Standring D, Gosselin G.
    Nucleosides Nucleotides Nucleic Acids; 2003 Aug; 22(5-8):1003-6. PubMed ID: 14565331
    [Abstract] [Full Text] [Related]

  • 3. Pharmacokinetics of the antiviral agent beta-L-3'-fluoro-2',3'-didehydro-2',3'-dideoxycytidine in rhesus monkeys.
    Asif G, Hurwitz SJ, Gumina G, Chu CK, McClure HM, Schinazi RF.
    Antimicrob Agents Chemother; 2005 Feb; 49(2):560-4. PubMed ID: 15673733
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, physicochemical and pharmacokinetic studies of potential prodrugs of beta-L-2'-deoxycytidine, a selective and specific anti-HBV agent.
    Pierra C, Benzaria S, Dukhan D, Loi AG, La Colla P, Bridges E, Mao J, Standring D, Sommadossi JP, Gosselin G.
    Antivir Chem Chemother; 2004 Sep; 15(5):269-79. PubMed ID: 15535049
    [Abstract] [Full Text] [Related]

  • 5. Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rhesus monkeys.
    Schinazi RF, Boudinot FD, Doshi KJ, McClure HM.
    Antimicrob Agents Chemother; 1990 Jun; 34(6):1214-9. PubMed ID: 2168144
    [Abstract] [Full Text] [Related]

  • 6. The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys.
    Kelley JA, Litterst CL, Roth JS, Vistica DT, Poplack DG, Cooney DA, Nadkarni M, Balis FM, Broder S, Johns DG.
    Drug Metab Dispos; 1987 Jun; 15(5):595-601. PubMed ID: 2891473
    [Abstract] [Full Text] [Related]

  • 7. Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.
    Ma H, Jiang WR, Robledo N, Leveque V, Ali S, Lara-Jaime T, Masjedizadeh M, Smith DB, Cammack N, Klumpp K, Symons J.
    J Biol Chem; 2007 Oct 12; 282(41):29812-20. PubMed ID: 17698842
    [Abstract] [Full Text] [Related]

  • 8. Pharmacokinetics and metabolism of 3'-azido-2',3'-dideoxy-5-methylcytidine in rhesus monkeys.
    Boudinot FD, Schinazi RF, Doshi KJ, McClure HM, Chu CK.
    Drug Metab Dispos; 1993 Oct 12; 21(5):855-60. PubMed ID: 7902248
    [Abstract] [Full Text] [Related]

  • 9. Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys.
    Schinazi RF, Boudinot FD, Ibrahim SS, Manning C, McClure HM, Liotta DC.
    Antimicrob Agents Chemother; 1992 Nov 12; 36(11):2432-8. PubMed ID: 1336946
    [Abstract] [Full Text] [Related]

  • 10. Pharmacokinetics, oral bioavailability, and metabolism in mice and cynomolgus monkeys of (2'R,5'S-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, an agent active against human immunodeficiency virus and human hepatitis B virus.
    Frick LW, Lambe CU, St John L, Taylor LC, Nelson DJ.
    Antimicrob Agents Chemother; 1994 Dec 12; 38(12):2722-9. PubMed ID: 7695253
    [Abstract] [Full Text] [Related]

  • 11. In vitro and in vivo metabolism and pharmacokinetics of bis [(t-butyl)-S-acyl-2-thioethyl]-beta-L-2',3'-dideoxy-5-fluorocytidine monophosphate.
    Martin LT, Cretton-Scott E, Placidi L, Faraj A, Loi AG, Schinazi RF, McClure HM, Gosselin G, Imbach JL, Sommadossi JP.
    Nucleosides Nucleotides Nucleic Acids; 2000 Dec 12; 19(1-2):481-99. PubMed ID: 10772729
    [Abstract] [Full Text] [Related]

  • 12. Pharmacokinetics of (-)-beta-D-dioxolane guanine and prodrug (-)-beta-D-2,6-diaminopurine dioxolane in rats and monkeys.
    Chen H, Schinazi RF, Rajagopalan P, Gao Z, Chu CK, McClure HM, Boudinot FD.
    AIDS Res Hum Retroviruses; 1999 Dec 10; 15(18):1625-30. PubMed ID: 10606085
    [Abstract] [Full Text] [Related]

  • 13. Pharmacokinetics of the antiviral agent beta-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys.
    Ma L, Hurwitz SJ, Shi J, Mcatee JJ, Liotta DC, McClure HM, Schinazi RF.
    Antimicrob Agents Chemother; 1999 Feb 10; 43(2):381-4. PubMed ID: 9925539
    [Abstract] [Full Text] [Related]

  • 14. The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
    Murakami E, Niu C, Bao H, Micolochick Steuer HM, Whitaker T, Nachman T, Sofia MA, Wang P, Otto MJ, Furman PA.
    Antimicrob Agents Chemother; 2008 Feb 10; 52(2):458-64. PubMed ID: 17999967
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.
    Pierra C, Amador A, Benzaria S, Cretton-Scott E, D'Amours M, Mao J, Mathieu S, Moussa A, Bridges EG, Standring DN, Sommadossi JP, Storer R, Gosselin G.
    J Med Chem; 2006 Nov 02; 49(22):6614-20. PubMed ID: 17064080
    [Abstract] [Full Text] [Related]

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  • 17. Pharmacokinetics of gemcitabine and its amino acid ester prodrug following intravenous and oral administrations in mice.
    Thompson BR, Shi J, Zhu HJ, Smith DE.
    Biochem Pharmacol; 2020 Oct 02; 180():114127. PubMed ID: 32603666
    [Abstract] [Full Text] [Related]

  • 18. Lack of dose dependent kinetics of methyl salicylate-2-O-β-D-lactoside in rhesus monkeys after oral administration.
    He Y, Yan Y, Zhang T, Ma Y, Zhang W, Wu P, Song J, Wang S, Du G.
    J Ethnopharmacol; 2015 Apr 22; 164():293-300. PubMed ID: 25571846
    [Abstract] [Full Text] [Related]

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  • 20. Pharmacokinetics of coumarin and 7-hydroxycoumarin in the rhesus monkey after intravenous and peroral administration.
    Ritschel WA, Denson DD, Grummich KW.
    Arzneimittelforschung; 1988 Nov 22; 38(11):1619-23. PubMed ID: 3214445
    [Abstract] [Full Text] [Related]

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