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641 related items for PubMed ID: 17569795

  • 1. Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated receptor gamma.
    Wei S, Lin LF, Yang CC, Wang YC, Chang GD, Chen H, Chen CS.
    Mol Pharmacol; 2007 Sep; 72(3):725-33. PubMed ID: 17569795
    [Abstract] [Full Text] [Related]

  • 2. A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells.
    Wei S, Yang HC, Chuang HC, Yang J, Kulp SK, Lu PJ, Lai MD, Chen CS.
    J Biol Chem; 2008 Sep 26; 283(39):26759-70. PubMed ID: 18650423
    [Abstract] [Full Text] [Related]

  • 3. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
    Bornstein G, Ganoth D, Hershko A.
    Proc Natl Acad Sci U S A; 2006 Aug 01; 103(31):11515-20. PubMed ID: 16861300
    [Abstract] [Full Text] [Related]

  • 4. Peroxisome proliferator-activated receptor gamma-independent suppression of androgen receptor expression by troglitazone mechanism and pharmacologic exploitation.
    Yang CC, Wang YC, Wei S, Lin LF, Chen CS, Lee CC, Lin CC, Chen CS.
    Cancer Res; 2007 Apr 01; 67(7):3229-38. PubMed ID: 17409431
    [Abstract] [Full Text] [Related]

  • 5. The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.
    Latres E, Chiaur DS, Pagano M.
    Oncogene; 1999 Jan 28; 18(4):849-54. PubMed ID: 10023660
    [Abstract] [Full Text] [Related]

  • 6. Role of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases in skin cancer.
    Xie CM, Wei W, Sun Y.
    J Genet Genomics; 2013 Mar 20; 40(3):97-106. PubMed ID: 23522382
    [Abstract] [Full Text] [Related]

  • 7. Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation.
    Zhang L, Zhou F, Li Y, Drabsch Y, Zhang J, van Dam H, ten Dijke P.
    J Biol Chem; 2012 Aug 31; 287(36):30701-10. PubMed ID: 22730322
    [Abstract] [Full Text] [Related]

  • 8. Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism.
    Emberley ED, Mosadeghi R, Deshaies RJ.
    J Biol Chem; 2012 Aug 24; 287(35):29679-89. PubMed ID: 22767593
    [Abstract] [Full Text] [Related]

  • 9. NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR.
    Kainulainen M, Lau S, Samuel CE, Hornung V, Weber F.
    J Virol; 2016 Jul 01; 90(13):6140-7. PubMed ID: 27122577
    [Abstract] [Full Text] [Related]

  • 10. Targeted degradation of beta-catenin by chimeric F-box fusion proteins.
    Liu J, Stevens J, Matsunami N, White RL.
    Biochem Biophys Res Commun; 2004 Jan 23; 313(4):1023-9. PubMed ID: 14706645
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.
    Gorelik M, Orlicky S, Sartori MA, Tang X, Marcon E, Kurinov I, Greenblatt JF, Tyers M, Moffat J, Sicheri F, Sidhu SS.
    Proc Natl Acad Sci U S A; 2016 Mar 29; 113(13):3527-32. PubMed ID: 26976582
    [Abstract] [Full Text] [Related]

  • 12. Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of beta-transducin repeat-containing protein.
    Wei S, Chuang HC, Tsai WC, Yang HC, Ho SR, Paterson AJ, Kulp SK, Chen CS.
    Mol Pharmacol; 2009 Jul 29; 76(1):47-57. PubMed ID: 19372209
    [Abstract] [Full Text] [Related]

  • 13. The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival.
    Peschiaroli A, Skaar JR, Pagano M, Melino G.
    Oncogene; 2010 Mar 04; 29(9):1384-93. PubMed ID: 19966869
    [Abstract] [Full Text] [Related]

  • 14. M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.
    Watanabe N, Arai H, Nishihara Y, Taniguchi M, Watanabe N, Hunter T, Osada H.
    Proc Natl Acad Sci U S A; 2004 Mar 30; 101(13):4419-24. PubMed ID: 15070733
    [Abstract] [Full Text] [Related]

  • 15. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M.
    J Biol Chem; 2015 Apr 17; 290(16):10368-81. PubMed ID: 25670854
    [Abstract] [Full Text] [Related]

  • 16. Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent.
    Wei S, Chu PC, Chuang HC, Hung WC, Kulp SK, Chen CS.
    PLoS One; 2012 Apr 17; 7(10):e47298. PubMed ID: 23071779
    [Abstract] [Full Text] [Related]

  • 17. The characteristics and roles of β-TrCP1/2 in carcinogenesis.
    Bi Y, Cui D, Xiong X, Zhao Y.
    FEBS J; 2021 Jun 17; 288(11):3351-3374. PubMed ID: 33021036
    [Abstract] [Full Text] [Related]

  • 18. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
    Koga H, Harada M, Ohtsubo M, Shishido S, Kumemura H, Hanada S, Taniguchi E, Yamashita K, Kumashiro R, Ueno T, Sata M.
    Hepatology; 2003 May 17; 37(5):1086-96. PubMed ID: 12717389
    [Abstract] [Full Text] [Related]

  • 19. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
    Pavlides SC, Huang KT, Reid DA, Wu L, Blank SV, Mittal K, Guo L, Rothenberg E, Rueda B, Cardozo T, Gold LI.
    Endocrinology; 2013 Nov 17; 154(11):4030-45. PubMed ID: 24035998
    [Abstract] [Full Text] [Related]

  • 20. Wnt/β-catenin signaling inhibits FBXW7 expression by upregulation of microRNA-770 in hepatocellular carcinoma.
    Wu WJ, Shi J, Hu G, Yu X, Lu H, Yang ML, Liu B, Wu ZX.
    Tumour Biol; 2016 May 17; 37(5):6045-51. PubMed ID: 26602384
    [Abstract] [Full Text] [Related]


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