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802 related items for PubMed ID: 17583925

  • 1. Reagents for astatination of biomolecules. 2. Conjugation of anionic boron cage pendant groups to a protein provides a method for direct labeling that is stable to in vivo deastatination.
    Wilbur DS, Chyan MK, Hamlin DK, Vessella RL, Wedge TJ, Hawthorne MF.
    Bioconjug Chem; 2007; 18(4):1226-40. PubMed ID: 17583925
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  • 3. Reagents for astatination of biomolecules. 5. Evaluation of hydrazone linkers in (211)At- and (125)I-labeled closo-decaborate(2-) conjugates of Fab' as a means of decreasing kidney retention.
    Wilbur DS, Chyan MK, Hamlin DK, Nguyen H, Vessella RL.
    Bioconjug Chem; 2011 Jun 15; 22(6):1089-102. PubMed ID: 21513347
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  • 6. Streptavidin in antibody pretargeting. 5. chemical modification of recombinant streptavidin for labeling with the alpha-particle-emitting radionuclides 213Bi and 211At.
    Wilbur DS, Hamlin DK, Chyan MK, Brechbiel MW.
    Bioconjug Chem; 2008 Jan 15; 19(1):158-70. PubMed ID: 18072725
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  • 7. Biotin reagents in antibody pretargeting. 6. Synthesis and in vivo evaluation of astatinated and radioiodinated aryl- and nido-carboranyl-biotin derivatives.
    Wilbur DS, Hamlin DK, Chyan MK, Kegley BB, Quinn J, Vessella RL.
    Bioconjug Chem; 2004 Jan 15; 15(3):601-16. PubMed ID: 15149189
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  • 8. Direct procedure for the production of 211At-labeled antibodies with an epsilon-lysyl-3-(trimethylstannyl)benzamide immunoconjugate.
    Lindegren S, Frost S, Bäck T, Haglund E, Elgqvist J, Jensen H.
    J Nucl Med; 2008 Sep 15; 49(9):1537-45. PubMed ID: 18703591
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  • 9. Comparative tissue distribution in mice of the alpha-emitter 211At and 131I as labels of a monoclonal antibody and F(ab')2 fragment.
    Garg PK, Harrison CL, Zalutsky MR.
    Cancer Res; 1990 Jun 15; 50(12):3514-20. PubMed ID: 2340501
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  • 10. High-linear energy transfer (LET) alpha versus low-LET beta emitters in radioimmunotherapy of solid tumors: therapeutic efficacy and dose-limiting toxicity of 213Bi- versus 90Y-labeled CO17-1A Fab' fragments in a human colonic cancer model.
    Behr TM, Béhé M, Stabin MG, Wehrmann E, Apostolidis C, Molinet R, Strutz F, Fayyazi A, Wieland E, Gratz S, Koch L, Goldenberg DM, Becker W.
    Cancer Res; 1999 Jun 01; 59(11):2635-43. PubMed ID: 10363986
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  • 11. Synthesis, radioiodination, and biodistribution of some nido- and closo-monocarbon carborane derivatives.
    Wilbur DS, Hamlin DK, Srivastava RR, Chyan MK.
    Nucl Med Biol; 2004 May 01; 31(4):523-30. PubMed ID: 15093823
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  • 12. Antibody fragments in tumor pretargeting. Evaluation of biotinylated Fab' colocalization with recombinant streptavidin and avidin.
    Wilbur DS, Hamlin DK, Vessella RL, Stray JE, Buhler KR, Stayton PS, Klumb LA, Pathare PM, Weerawarna SA.
    Bioconjug Chem; 1996 May 01; 7(6):689-702. PubMed ID: 8950488
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  • 13. 211At- and 131I-labeled bisphosphonates with high in vivo stability and bone accumulation.
    Larsen RH, Murud KM, Akabani G, Hoff P, Bruland OS, Zalutsky MR.
    J Nucl Med; 1999 Jul 01; 40(7):1197-203. PubMed ID: 10405142
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  • 14. The pharmacokinetic characteristics of glycolated humanized anti-Tac Fabs are determined by their isoelectric points.
    Kobayashi H, Le N, Kim IS, Kim MK, Pie JE, Drumm D, Paik DS, Waldmann TA, Paik CH, Carrasquillo JA.
    Cancer Res; 1999 Jan 15; 59(2):422-30. PubMed ID: 9927057
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  • 15. Closo-dodecaborate(2-) as a linker for iodination of macromolecules. Aspects on conjugation chemistry and biodistribution.
    Tolmachev V, Koziorowski J, Sivaev I, Lundqvist H, Carlsson J, Orlova A, Gedda L, Olsson P, Sjöberg S, Sundin A.
    Bioconjug Chem; 1999 Jan 15; 10(3):338-45. PubMed ID: 10346862
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  • 16. Biodistribution of 211At labeled HER-2 binding affibody molecules in mice.
    Steffen AC, Almqvist Y, Chyan MK, Lundqvist H, Tolmachev V, Wilbur DS, Carlsson J.
    Oncol Rep; 2007 May 15; 17(5):1141-7. PubMed ID: 17390057
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  • 17. Reagents for astatination of biomolecules. 6. An intact antibody conjugated with a maleimido-closo-decaborate(2-) reagent via sulfhydryl groups had considerably higher kidney concentrations than the same antibody conjugated with an isothiocyanato-closo-decaborate(2-) reagent via lysine amines.
    Wilbur DS, Chyan MK, Nakamae H, Chen Y, Hamlin DK, Santos EB, Kornblit BT, Sandmaier BM.
    Bioconjug Chem; 2012 Mar 21; 23(3):409-20. PubMed ID: 22296587
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  • 18. Biotin reagents for antibody pretargeting. 3. Synthesis, radioiodination, and evaluation of biotinylated starburst dendrimers.
    Wilbur DS, Pathare PM, Hamlin DK, Buhler KR, Vessella RL.
    Bioconjug Chem; 1998 Mar 21; 9(6):813-25. PubMed ID: 9815176
    [Abstract] [Full Text] [Related]

  • 19. Tumor imaging with technetium-99m-labeled hydrazinonicotinamide-Fab' conjugates.
    Ultee ME, Bridger GJ, Abrams MJ, Longley CB, Burton CA, Larsen SK, Henson GW, Padmanabhan S, Gaul FE, Schwartz DA.
    J Nucl Med; 1997 Jan 21; 38(1):133-8. PubMed ID: 8998167
    [Abstract] [Full Text] [Related]

  • 20. Astatine-211 labeling of an antimelanoma antibody and its Fab fragment using N-succinimidyl p-astatobenzoate: comparisons in vivo with the p-[125I]iodobenzoyl conjugate.
    Hadley SW, Wilbur DS, Gray MA, Atcher RW.
    Bioconjug Chem; 1991 Jan 21; 2(3):171-9. PubMed ID: 1932216
    [Abstract] [Full Text] [Related]


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