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289 related items for PubMed ID: 17583927

  • 1. Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate.
    Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL.
    Bioconjug Chem; 2007; 18(4):1325-31. PubMed ID: 17583927
    [Abstract] [Full Text] [Related]

  • 2. Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.
    Youngblood DS, Hatlevig SA, Hassinger JN, Iversen PL, Moulton HM.
    Bioconjug Chem; 2007; 18(1):50-60. PubMed ID: 17226957
    [Abstract] [Full Text] [Related]

  • 3. Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity.
    Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM.
    Bioconjug Chem; 2005; 16(4):959-66. PubMed ID: 16029037
    [Abstract] [Full Text] [Related]

  • 4. Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo.
    Moulton HM, Fletcher S, Neuman BW, McClorey G, Stein DA, Abes S, Wilton SD, Buchmeier MJ, Lebleu B, Iversen PL.
    Biochem Soc Trans; 2007 Aug; 35(Pt 4):826-8. PubMed ID: 17635157
    [Abstract] [Full Text] [Related]

  • 5. Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides.
    Moulton HM, Nelson MH, Hatlevig SA, Reddy MT, Iversen PL.
    Bioconjug Chem; 2004 Aug; 15(2):290-9. PubMed ID: 15025524
    [Abstract] [Full Text] [Related]

  • 6. Antisense peptide-phosphorodiamidate morpholino oligomer conjugate: dose-response in mice infected with Escherichia coli.
    Tilley LD, Mellbye BL, Puckett SE, Iversen PL, Geller BL.
    J Antimicrob Chemother; 2007 Jan; 59(1):66-73. PubMed ID: 17079242
    [Abstract] [Full Text] [Related]

  • 7. In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors.
    Devi GR, Beer TM, Corless CL, Arora V, Weller DL, Iversen PL.
    Clin Cancer Res; 2005 May 15; 11(10):3930-8. PubMed ID: 15897595
    [Abstract] [Full Text] [Related]

  • 8. Pharmacokinetics and biodistribution of the camptothecin-polymer conjugate IT-101 in rats and tumor-bearing mice.
    Schluep T, Cheng J, Khin KT, Davis ME.
    Cancer Chemother Pharmacol; 2006 May 15; 57(5):654-62. PubMed ID: 16133526
    [Abstract] [Full Text] [Related]

  • 9. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials.
    Food Chem Toxicol; 2008 Mar 15; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [Abstract] [Full Text] [Related]

  • 10. Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.
    Abes S, Moulton HM, Clair P, Prevot P, Youngblood DS, Wu RP, Iversen PL, Lebleu B.
    J Control Release; 2006 Dec 01; 116(3):304-13. PubMed ID: 17097177
    [Abstract] [Full Text] [Related]

  • 11. Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing.
    Marshall NB, Oda SK, London CA, Moulton HM, Iversen PL, Kerkvliet NI, Mourich DV.
    J Immunol Methods; 2007 Aug 31; 325(1-2):114-26. PubMed ID: 17673254
    [Abstract] [Full Text] [Related]

  • 12. Inducing a change in the pharmacokinetics and biodistribution of poly-L-lysine in rats by complexation with heparin.
    Johnston TP, Kuchimanchi KR, Alur H, Chittchang M, Mitra AK.
    J Pharm Pharmacol; 2003 Aug 31; 55(8):1083-90. PubMed ID: 12956897
    [Abstract] [Full Text] [Related]

  • 13. Pharmacokinetics and biodistribution of phosphorodiamidate morpholino antisense oligomers.
    Amantana A, Iversen PL.
    Curr Opin Pharmacol; 2005 Oct 31; 5(5):550-5. PubMed ID: 16087398
    [Abstract] [Full Text] [Related]

  • 14. Dose-dependent toxicokinetics of L-689,502, a potent human immunodeficiency virus protease inhibitor, in rats and dogs.
    Lin JH, Chen IW, King J.
    J Pharmacol Exp Ther; 1992 Oct 31; 263(1):105-11. PubMed ID: 1403775
    [Abstract] [Full Text] [Related]

  • 15. Gene-specific effects of antisense phosphorodiamidate morpholino oligomer-peptide conjugates on Escherichia coli and Salmonella enterica serovar typhimurium in pure culture and in tissue culture.
    Tilley LD, Hine OS, Kellogg JA, Hassinger JN, Weller DD, Iversen PL, Geller BL.
    Antimicrob Agents Chemother; 2006 Aug 31; 50(8):2789-96. PubMed ID: 16870773
    [Abstract] [Full Text] [Related]

  • 16. Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity.
    Wu RP, Youngblood DS, Hassinger JN, Lovejoy CE, Nelson MH, Iversen PL, Moulton HM.
    Nucleic Acids Res; 2007 Aug 31; 35(15):5182-91. PubMed ID: 17670797
    [Abstract] [Full Text] [Related]

  • 17. Plasma pharmacokinetics and tissue distribution of [6]-gingerol in rats.
    Jiang SZ, Wang NS, Mi SQ.
    Biopharm Drug Dispos; 2008 Dec 31; 29(9):529-37. PubMed ID: 19051331
    [Abstract] [Full Text] [Related]

  • 18. Biodistribution, plasma kinetics and quantification of single-pass pulmonary clearance of adrenomedullin.
    Dupuis J, Caron A, Ruël N.
    Clin Sci (Lond); 2005 Jul 31; 109(1):97-102. PubMed ID: 15740458
    [Abstract] [Full Text] [Related]

  • 19. Antisense phosphorodiamidate morpholino oligomer inhibits viability of Escherichia coli in pure culture and in mouse peritonitis.
    Geller BL, Deere J, Tilley L, Iversen PL.
    J Antimicrob Chemother; 2005 Jun 31; 55(6):983-8. PubMed ID: 15872045
    [Abstract] [Full Text] [Related]

  • 20. A comparison of in vitro and in vivo stability in mice of two morpholino duplexes differing in chain length.
    He J, Liu G, Zhang S, Vanderheyden JL, Liu N, Liu C, Zhang Y, Gupta S, Rusckowski M, Hnatowich DJ.
    Bioconjug Chem; 2003 Jun 31; 14(5):1018-23. PubMed ID: 13129406
    [Abstract] [Full Text] [Related]

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