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Journal Abstract Search

769 related items for PubMed ID: 17585747

  • 1. Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents.
    Wei L, Shi Q, Bastow KF, Brossi A, Morris-Natschke SL, Nakagawa-Goto K, Wu TS, Pan SL, Teng CM, Lee KH.
    J Med Chem; 2007 Jul 26; 50(15):3674-80. PubMed ID: 17585747
    [Abstract] [Full Text] [Related]

  • 2. Antitumor agents 251: synthesis, cytotoxic evaluation, and structure-activity relationship studies of phenanthrene-based tylophorine derivatives (PBTs) as a new class of antitumor agents.
    Wei L, Brossi A, Kendall R, Bastow KF, Morris-Natschke SL, Shi Q, Lee KH.
    Bioorg Med Chem; 2006 Oct 01; 14(19):6560-9. PubMed ID: 16809043
    [Abstract] [Full Text] [Related]

  • 3. Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids.
    Chuang TH, Lee SJ, Yang CW, Wu PL.
    Org Biomol Chem; 2006 Mar 07; 4(5):860-7. PubMed ID: 16493470
    [Abstract] [Full Text] [Related]

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  • 5. Synthesis of phenanthroindolizidine alkaloids and evaluation of their antitumor activities and toxicities.
    Ikeda T, Yaegashi T, Matsuzaki T, Yamazaki R, Hashimoto S, Sawada S.
    Bioorg Med Chem Lett; 2011 Oct 01; 21(19):5978-81. PubMed ID: 21865039
    [Abstract] [Full Text] [Related]

  • 6. Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents.
    Yang X, Shi Q, Liu YN, Zhao G, Bastow KF, Lin JC, Yang SC, Yang PC, Lee KH.
    J Med Chem; 2009 Aug 27; 52(16):5262-8. PubMed ID: 19645447
    [Abstract] [Full Text] [Related]

  • 7. Design, Synthesis and in Vitro Evaluation of Tylophorine Derivatives as Possible Antitumor Agents.
    Mang Z, Zhang S, Bai J, Li M, Li H.
    Chem Biodivers; 2020 Sep 27; 17(9):e2000066. PubMed ID: 32567792
    [Abstract] [Full Text] [Related]

  • 8. Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
    Engel D, Nudelman A, Tarasenko N, Levovich I, Makarovsky I, Sochotnikov S, Tarasenko I, Rephaeli A.
    J Med Chem; 2008 Jan 24; 51(2):314-23. PubMed ID: 18163551
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  • 9. Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.
    Varvaresou A, Iakovou K, Gikas E, Fichtner I, Fiebig HH, Kelland LR, Double JA, Bibby MC, Hendriks HR.
    Anticancer Res; 2004 Jan 24; 24(2B):907-19. PubMed ID: 15161044
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
    Wang K, Hu Y, Liu Y, Mi N, Fan Z, Liu Y, Wang Q.
    J Agric Food Chem; 2010 Dec 08; 58(23):12337-42. PubMed ID: 21058739
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.
    Christensen MK, Erichsen KD, Trojel-Hansen C, Tjørnelund J, Nielsen SJ, Frydenvang K, Johansen TN, Nielsen B, Sehested M, Jensen PB, Ikaunieks M, Zaichenko A, Loza E, Kalvinsh I, Björkling F.
    J Med Chem; 2010 Oct 14; 53(19):7140-5. PubMed ID: 20845961
    [Abstract] [Full Text] [Related]

  • 12. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U, Lynch J, Sato Y, Kashimoto S, Kajikawa F, Furutani Y, Silverman JA.
    Cancer Chemother Pharmacol; 2009 Jun 14; 64(1):53-65. PubMed ID: 18931998
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  • 13. Antitumor agents 260. New desmosdumotin B analogues with improved in vitro anticancer activity.
    Nakagawa-Goto K, Bastow KF, Chen TH, Morris-Natschke SL, Lee KH.
    J Med Chem; 2008 Jun 12; 51(11):3297-303. PubMed ID: 18473435
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  • 14. Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents.
    Xue N, Yang X, Wu R, Chen J, He Q, Yang B, Lu X, Hu Y.
    Bioorg Med Chem; 2008 Mar 01; 16(5):2550-7. PubMed ID: 18226907
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  • 15. Synthesis and evaluation of C-ring aromatized analogues of phenanthridone alkaloids.
    Lee S, Hwang S, Yu S, Jang W, Lee YM, Kim S.
    Arch Pharm Res; 2011 Jul 01; 34(7):1065-70. PubMed ID: 21811912
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  • 16. Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.
    Wang YQ, Li XH, He Q, Chen Y, Xie YY, Ding J, Miao ZH, Yang CH.
    Eur J Med Chem; 2011 Dec 01; 46(12):5878-84. PubMed ID: 22000922
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: exploration of the role of tylophorine e ring on biological activity.
    Lee YZ, Yang CW, Hsu HY, Qiu YQ, Yeh TK, Chang HY, Chao YS, Lee SJ.
    J Med Chem; 2012 Dec 13; 55(23):10363-77. PubMed ID: 23167614
    [Abstract] [Full Text] [Related]

  • 18. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK, Guan J, Tachibana Y, Bastow KF, Cho SJ, Cheng HH, Cheng YC, Gurwith M, Lee KH.
    J Med Chem; 1999 Jul 01; 42(13):2441-6. PubMed ID: 10395485
    [Abstract] [Full Text] [Related]

  • 19. Structure-activity studies of phenanthroindolizidine alkaloids as potential antitumor agents.
    Gao W, Bussom S, Grill SP, Gullen EA, Hu YC, Huang X, Zhong S, Kaczmarek C, Gutierrez J, Francis S, Baker DC, Yu S, Cheng YC.
    Bioorg Med Chem Lett; 2007 Aug 01; 17(15):4338-42. PubMed ID: 17531481
    [Abstract] [Full Text] [Related]

  • 20. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
    Leese MP, Jourdan FL, Gaukroger K, Mahon MF, Newman SP, Foster PA, Stengel C, Regis-Lydi S, Ferrandis E, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV.
    J Med Chem; 2008 Mar 13; 51(5):1295-308. PubMed ID: 18260615
    [Abstract] [Full Text] [Related]

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