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201 related items for PubMed ID: 17585979
1. Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate. Moffit JS, Koza-Taylor PH, Holland RD, Thibodeau MS, Beger RD, Lawton MP, Manautou JE. Toxicol Appl Pharmacol; 2007 Jul 15; 222(2):169-79. PubMed ID: 17585979 [Abstract] [Full Text] [Related]
3. Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses. Ferreira DW, Goedken MJ, Rommelaere S, Chasson L, Galland F, Naquet P, Manautou JE. Biochim Biophys Acta; 2016 Apr 15; 1862(4):662-669. PubMed ID: 26850476 [Abstract] [Full Text] [Related]
4. Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen. Moffit JS, Aleksunes LM, Kardas MJ, Slitt AL, Klaassen CD, Manautou JE. Toxicology; 2007 Feb 12; 230(2-3):197-206. PubMed ID: 17188792 [Abstract] [Full Text] [Related]
5. Protection against acetaminophen hepatotoxicity by clofibrate pretreatment: role of catalase induction. Chen C, Hennig GE, Whiteley HE, Manautou JE. J Biochem Mol Toxicol; 2002 Feb 12; 16(5):227-34. PubMed ID: 12439864 [Abstract] [Full Text] [Related]
6. The PPAR activator docosahexaenoic acid prevents acetaminophen hepatotoxicity in male CD-1 mice. Nguyen KA, Carbone JM, Silva VM, Chen C, Hennig GE, Whiteley HE, Manautou JE. J Toxicol Environ Health A; 1999 Oct 15; 58(3):171-86. PubMed ID: 10522648 [Abstract] [Full Text] [Related]
7. Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion. Manautou JE, Emeigh Hart SG, Khairallah EA, Cohen SD. Fundam Appl Toxicol; 1996 Feb 15; 29(2):229-37. PubMed ID: 8742320 [Abstract] [Full Text] [Related]
8. Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection). O'Connor MA, Koza-Taylor P, Campion SN, Aleksunes LM, Gu X, Enayetallah AE, Lawton MP, Manautou JE. Toxicol Appl Pharmacol; 2014 Jan 01; 274(1):156-67. PubMed ID: 24126418 [Abstract] [Full Text] [Related]
9. Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor. Ren H, Aleksunes LM, Wood C, Vallanat B, George MH, Klaassen CD, Corton JC. Toxicol Sci; 2010 Jan 01; 113(1):45-59. PubMed ID: 19850644 [Abstract] [Full Text] [Related]
10. Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity. Manautou JE, Hoivik DJ, Tveit A, Hart SG, Khairallah EA, Cohen SD. Toxicol Appl Pharmacol; 1994 Dec 01; 129(2):252-63. PubMed ID: 7992315 [Abstract] [Full Text] [Related]
11. Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofibrate is regulated by peroxisome proliferator-activated receptor alpha. Moffit JS, Aleksunes LM, Maher JM, Scheffer GL, Klaassen CD, Manautou JE. J Pharmacol Exp Ther; 2006 May 01; 317(2):537-45. PubMed ID: 16467456 [Abstract] [Full Text] [Related]
12. PPAR-alpha: a key to the mechanism of hepatoprotection by clofibrate. Mehendale HM. Toxicol Sci; 2000 Oct 01; 57(2):187-90. PubMed ID: 11006348 [Abstract] [Full Text] [Related]
13. Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophen-glutathione adducts. Manautou JE, Tveit A, Hoivik DJ, Khairallah EA, Cohen SD. Toxicol Appl Pharmacol; 1996 Sep 01; 140(1):30-8. PubMed ID: 8806867 [Abstract] [Full Text] [Related]
14. Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity. Li D, Du Y, Yuan X, Han X, Dong Z, Chen X, Wu H, Zhang J, Xu L, Han C, Zhang M, Xia Q. Free Radic Biol Med; 2017 Sep 01; 110():102-116. PubMed ID: 28583670 [Abstract] [Full Text] [Related]
15. Differential induction of genes in liver and brown adipose tissue regulated by peroxisome proliferator-activated receptor-alpha during fasting and cold exposure in acyl-CoA dehydrogenase-deficient mice. Goetzman ES, Tian L, Wood PA. Mol Genet Metab; 2005 Jan 01; 84(1):39-47. PubMed ID: 15639194 [Abstract] [Full Text] [Related]
16. Repeated dosing with the peroxisome proliferator clofibrate decreases the toxicity of model hepatotoxic agents in male mice. Manautou JE, Silva VM, Hennig GE, Whiteley HE. Toxicology; 1998 May 15; 127(1-3):1-10. PubMed ID: 9699788 [Abstract] [Full Text] [Related]
17. Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARalpha with clofibrate. Donthamsetty S, Bhave VS, Mitra MS, Latendresse JR, Mehendale HM. Toxicol Appl Pharmacol; 2008 Aug 01; 230(3):327-37. PubMed ID: 18501395 [Abstract] [Full Text] [Related]
18. Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity. Patterson AD, Shah YM, Matsubara T, Krausz KW, Gonzalez FJ. Hepatology; 2012 Jul 01; 56(1):281-90. PubMed ID: 22318764 [Abstract] [Full Text] [Related]
19. Feeding oxidized fat during pregnancy up-regulates expression of PPARalpha-responsive genes in the liver of rat fetuses. Ringseis R, Gutgesell A, Dathe C, Brandsch C, Eder K. Lipids Health Dis; 2007 Mar 12; 6():6. PubMed ID: 17352811 [Abstract] [Full Text] [Related]
20. Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha. Voss KA, Liu J, Anderson SP, Dunn C, Miller JD, Owen JR, Riley RT, Bacon CW, Corton JC. Toxicol Sci; 2006 Jan 12; 89(1):108-19. PubMed ID: 16221962 [Abstract] [Full Text] [Related] Page: [Next] [New Search]