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480 related items for PubMed ID: 17595514

  • 1. H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion.
    Furukawa A, Tada-Oikawa S, Kawanishi S, Oikawa S.
    Cell Physiol Biochem; 2007; 20(1-4):45-54. PubMed ID: 17595514
    [Abstract] [Full Text] [Related]

  • 2. Sirt1 modulates premature senescence-like phenotype in human endothelial cells.
    Ota H, Akishita M, Eto M, Iijima K, Kaneki M, Ouchi Y.
    J Mol Cell Cardiol; 2007 Nov; 43(5):571-9. PubMed ID: 17916362
    [Abstract] [Full Text] [Related]

  • 3. PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD+ levels and increasing SIRT1 activity.
    Zha S, Li Z, Cao Q, Wang F, Liu F.
    Stem Cell Res Ther; 2018 Aug 23; 9(1):224. PubMed ID: 30139380
    [Abstract] [Full Text] [Related]

  • 4. SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts.
    Huang J, Gan Q, Han L, Li J, Zhang H, Sun Y, Zhang Z, Tong T.
    PLoS One; 2008 Mar 05; 3(3):e1710. PubMed ID: 18320031
    [Abstract] [Full Text] [Related]

  • 5. Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism.
    Xiang QY, Tian F, Du X, Xu J, Zhu LY, Guo LL, Wen T, Liu YS, Liu L.
    Aging (Albany NY); 2020 Dec 09; 12(24):26080-26094. PubMed ID: 33316776
    [Abstract] [Full Text] [Related]

  • 6. Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1.
    Zhuge CC, Xu JY, Zhang J, Li W, Li P, Li Z, Chen L, Liu X, Shang P, Xu H, Lu Y, Wang F, Lu L, Xu GT.
    Invest Ophthalmol Vis Sci; 2014 May 20; 55(7):4628-38. PubMed ID: 24845634
    [Abstract] [Full Text] [Related]

  • 7. Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation.
    Kao CL, Chen LK, Chang YL, Yung MC, Hsu CC, Chen YC, Lo WL, Chen SJ, Ku HH, Hwang SJ.
    J Atheroscler Thromb; 2010 Sep 30; 17(9):970-9. PubMed ID: 20644332
    [Abstract] [Full Text] [Related]

  • 8. Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.
    Kim EJ, Kho JH, Kang MR, Um SJ.
    Mol Cell; 2007 Oct 26; 28(2):277-90. PubMed ID: 17964266
    [Abstract] [Full Text] [Related]

  • 9. Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation.
    Kume S, Haneda M, Kanasaki K, Sugimoto T, Araki S, Isono M, Isshiki K, Uzu T, Kashiwagi A, Koya D.
    Free Radic Biol Med; 2006 Jun 15; 40(12):2175-82. PubMed ID: 16785031
    [Abstract] [Full Text] [Related]

  • 10. Metoprolol Protects Against Arginine Vasopressin-Induced Cellular Senescence in H9C2 Cardiomyocytes by Regulating the Sirt1/p53/p21 Axis.
    Li Q, Huang K, Ma T, Lu S, Tang S, Wu M, Yang H, Zhong J.
    Cardiovasc Toxicol; 2022 Feb 15; 22(2):99-107. PubMed ID: 34800264
    [Abstract] [Full Text] [Related]

  • 11. Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence.
    Poulsen RC, Watts AC, Murphy RJ, Snelling SJ, Carr AJ, Hulley PA.
    Ann Rheum Dis; 2014 Jul 15; 73(7):1405-13. PubMed ID: 23727633
    [Abstract] [Full Text] [Related]

  • 12. Preventive effects of epigallocatechin-3-O-gallate against replicative senescence associated with p53 acetylation in human dermal fibroblasts.
    Han DW, Lee MH, Kim B, Lee JJ, Hyon SH, Park JC.
    Oxid Med Cell Longev; 2012 Jul 15; 2012():850684. PubMed ID: 23259030
    [Abstract] [Full Text] [Related]

  • 13. Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway.
    Wang G, Fu Y, Hu F, Lan J, Xu F, Yang X, Luo X, Wang J, Hu J.
    Cell Death Dis; 2017 Feb 09; 8(2):e2607. PubMed ID: 28182012
    [Abstract] [Full Text] [Related]

  • 14. Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells.
    Ota H, Eto M, Kano MR, Ogawa S, Iijima K, Akishita M, Ouchi Y.
    Arterioscler Thromb Vasc Biol; 2008 Sep 09; 28(9):1634-9. PubMed ID: 18556572
    [Abstract] [Full Text] [Related]

  • 15. Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.
    Ke Y, Li D, Zhao M, Liu C, Liu J, Zeng A, Shi X, Cheng S, Pan B, Zheng L, Hong H.
    Free Radic Biol Med; 2018 Feb 20; 116():88-100. PubMed ID: 29325896
    [Abstract] [Full Text] [Related]

  • 16. Apigenin Alleviates Oxidative Stress-Induced Cellular Senescence via Modulation of the SIRT1-NAD[Formula: see text]-CD38 Axis.
    Li BS, Zhu RZ, Lim SH, Seo JH, Choi BM.
    Am J Chin Med; 2021 Feb 20; 49(5):1235-1250. PubMed ID: 34049472
    [Abstract] [Full Text] [Related]

  • 17. Anti-oxidative and anti-aging activities of 2-O-α-glucopyranosyl-L-ascorbic acid on human dermal fibroblasts.
    Taniguchi M, Arai N, Kohno K, Ushio S, Fukuda S.
    Eur J Pharmacol; 2012 Jan 15; 674(2-3):126-31. PubMed ID: 22119379
    [Abstract] [Full Text] [Related]

  • 18. Measurements of hydrogen peroxide induced premature senescence: senescence-associated beta-galactosidase and DNA synthesis index in human diploid fibroblasts with down-regulated p53 or Rb.
    Chen QM, Tu VC, Liu J.
    Biogerontology; 2000 Jan 15; 1(4):335-9. PubMed ID: 11708215
    [Abstract] [Full Text] [Related]

  • 19. Human Sir2 and the 'silencing' of p53 activity.
    Smith J.
    Trends Cell Biol; 2002 Sep 15; 12(9):404-6. PubMed ID: 12220851
    [Abstract] [Full Text] [Related]

  • 20. Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence.
    Zdanov S, Debacq-Chainiaux F, Toussaint O.
    Ann N Y Acad Sci; 2007 Apr 15; 1100():316-22. PubMed ID: 17460194
    [Abstract] [Full Text] [Related]

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