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136 related items for PubMed ID: 17596526

  • 1. Knockdown of endosomal/lysosomal divalent metal transporter 1 by RNA interference prevents cadmium-metallothionein-1 cytotoxicity in renal proximal tubule cells.
    Abouhamed M, Wolff NA, Lee WK, Smith CP, Thévenod F.
    Am J Physiol Renal Physiol; 2007 Sep; 293(3):F705-12. PubMed ID: 17596526
    [Abstract] [Full Text] [Related]

  • 2. Divalent metal transporter 1 in the kidney proximal tubule is expressed in late endosomes/lysosomal membranes: implications for renal handling of protein-metal complexes.
    Abouhamed M, Gburek J, Liu W, Torchalski B, Wilhelm A, Wolff NA, Christensen EI, Thévenod F, Smith CP.
    Am J Physiol Renal Physiol; 2006 Jun; 290(6):F1525-33. PubMed ID: 16449358
    [Abstract] [Full Text] [Related]

  • 3. Role of ARF6 in internalization of metal-binding proteins, metallothionein and transferrin, and cadmium-metallothionein toxicity in kidney proximal tubule cells.
    Wolff NA, Lee WK, Abouhamed M, Thévenod F.
    Toxicol Appl Pharmacol; 2008 Jul 01; 230(1):78-85. PubMed ID: 18353411
    [Abstract] [Full Text] [Related]

  • 4. Megalin-dependent internalization of cadmium-metallothionein and cytotoxicity in cultured renal proximal tubule cells.
    Wolff NA, Abouhamed M, Verroust PJ, Thévenod F.
    J Pharmacol Exp Ther; 2006 Aug 01; 318(2):782-91. PubMed ID: 16690719
    [Abstract] [Full Text] [Related]

  • 5. Apoptosis by Cd2+ or CdMT in proximal tubule cells: different uptake routes and permissive role of endo/lysosomal CdMT uptake.
    Erfurt C, Roussa E, Thévenod F.
    Am J Physiol Cell Physiol; 2003 Dec 01; 285(6):C1367-76. PubMed ID: 12890648
    [Abstract] [Full Text] [Related]

  • 6. Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells.
    Fujishiro H, Yano Y, Takada Y, Tanihara M, Himeno S.
    Metallomics; 2012 Jul 01; 4(7):700-8. PubMed ID: 22534978
    [Abstract] [Full Text] [Related]

  • 7. Role of Arf1 in endosomal trafficking of protein-metal complexes and cadmium-metallothionein-1 toxicity in kidney proximal tubule cells.
    Wolff NA, Lee WK, Thévenod F.
    Toxicol Lett; 2011 Jun 24; 203(3):210-8. PubMed ID: 21421027
    [Abstract] [Full Text] [Related]

  • 8. Nephrotoxicity of CdCl2 and Cd-metallothionein in cultured rat kidney proximal tubules and LLC-PK1 cells.
    Liu J, Liu Y, Klaassen CD.
    Toxicol Appl Pharmacol; 1994 Oct 24; 128(2):264-70. PubMed ID: 7940541
    [Abstract] [Full Text] [Related]

  • 9. Discrepancy between the nephrotoxic potencies of cadmium-metallothionein and cadmium chloride and the renal concentration of cadmium in the proximal convoluted tubules.
    Dorian C, Gattone VH, Klaassen CD.
    Toxicol Appl Pharmacol; 1995 Jan 24; 130(1):161-8. PubMed ID: 7839364
    [Abstract] [Full Text] [Related]

  • 10. Cadmium-Metallothionein nephropathy: relationships between ultrastructural/biochemical alterations and intracellular cadmium binding.
    Squibb KS, Pritchard JB, Fowler BA.
    J Pharmacol Exp Ther; 1984 Apr 24; 229(1):311-21. PubMed ID: 6707945
    [Abstract] [Full Text] [Related]

  • 11. Increased Endocytosis of Cadmium-Metallothionein through the 24p3 Receptor in an In Vivo Model with Reduced Proximal Tubular Activity.
    Zavala-Guevara IP, Ortega-Romero MS, Narváez-Morales J, Jacobo-Estrada TL, Lee WK, Arreola-Mendoza L, Thévenod F, Barbier OC.
    Int J Mol Sci; 2021 Jul 06; 22(14):. PubMed ID: 34298880
    [Abstract] [Full Text] [Related]

  • 12. Transport pathways for cadmium in the intestine and kidney proximal tubule: focus on the interaction with essential metals.
    Vesey DA.
    Toxicol Lett; 2010 Sep 15; 198(1):13-9. PubMed ID: 20471461
    [Abstract] [Full Text] [Related]

  • 13. Nephrotoxicity and the proximal tubule. Insights from cadmium.
    Thévenod F.
    Nephron Physiol; 2003 Sep 15; 93(4):p87-93. PubMed ID: 12759569
    [Abstract] [Full Text] [Related]

  • 14. Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule.
    Fels J, Scharner B, Zarbock R, Zavala Guevara IP, Lee WK, Barbier OC, Thévenod F.
    Int J Mol Sci; 2019 May 14; 20(10):. PubMed ID: 31091675
    [Abstract] [Full Text] [Related]

  • 15. Cadmium induces nuclear translocation of beta-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells.
    Thévenod F, Wolff NA, Bork U, Lee WK, Abouhamed M.
    Biometals; 2007 Oct 14; 20(5):807-20. PubMed ID: 17136310
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of cadmium-metallothionein-induced nephrotoxicity: relationship to altered renal calcium metabolism.
    Fowler BA, Goering PL, Squibb KS.
    Experientia Suppl; 1987 Oct 14; 52():661-8. PubMed ID: 2822468
    [Abstract] [Full Text] [Related]

  • 17. Nephrotoxicity of cadmium-metallothionein: protection by zinc and role of glutathione.
    Tang W, Sadovic S, Shaikh ZA.
    Toxicol Appl Pharmacol; 1998 Aug 14; 151(2):276-82. PubMed ID: 9707504
    [Abstract] [Full Text] [Related]

  • 18. Comparative effects of Cd2+ and Cd-metallothionein on cultured kidney tubule cells.
    Blumenthal S, Lewand D, Krezoski SK, Petering DH.
    Toxicol Appl Pharmacol; 1996 Feb 14; 136(2):220-8. PubMed ID: 8619229
    [Abstract] [Full Text] [Related]

  • 19. Renal cortical mitochondrial dysfunction upon cadmium metallothionein administration to Sprague-Dawley rats.
    Tang W, Shaikh ZA.
    J Toxicol Environ Health A; 2001 Jun 08; 63(3):221-35. PubMed ID: 11405417
    [Abstract] [Full Text] [Related]

  • 20. Accumulation and degradation of the protein moiety of cadmium-metallothionein (CdMT) in the mouse kidney.
    Dorian C, Gattone VH, Klaassen CD.
    Toxicol Appl Pharmacol; 1992 Dec 08; 117(2):242-8. PubMed ID: 1471157
    [Abstract] [Full Text] [Related]

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