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Journal Abstract Search


285 related items for PubMed ID: 17604333

  • 1. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.
    Mol Cancer Ther; 2007 Jul; 6(7):2029-38. PubMed ID: 17604333
    [Abstract] [Full Text] [Related]

  • 2. Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
    Tazzari PL, Tabellini G, Ricci F, Papa V, Bortul R, Chiarini F, Evangelisti C, Martinelli G, Bontadini A, Cocco L, McCubrey JA, Martelli AM.
    Cancer Res; 2008 Nov 15; 68(22):9394-403. PubMed ID: 19010914
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  • 4. Dissecting the roles of DR4, DR5 and c-FLIP in the regulation of geranylgeranyltransferase I inhibition-mediated augmentation of TRAIL-induced apoptosis.
    Chen S, Fu L, Raja SM, Yue P, Khuri FR, Sun SY.
    Mol Cancer; 2010 Jan 29; 9():23. PubMed ID: 20113484
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  • 5. Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.
    Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG, Longley DB.
    Cell Death Differ; 2009 Oct 29; 16(10):1352-61. PubMed ID: 19543235
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  • 6. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X, Yue P, Chen S, Hu L, Lonial S, Khuri FR, Sun SY.
    Cancer Res; 2007 May 15; 67(10):4981-8. PubMed ID: 17510429
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  • 8. Perifosine synergistically enhances TRAIL-induced myeloma cell apoptosis via up-regulation of death receptors.
    David E, Sinha R, Chen J, Sun SY, Kaufman JL, Lonial S.
    Clin Cancer Res; 2008 Aug 15; 14(16):5090-8. PubMed ID: 18698026
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  • 9. Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions.
    Zhuang H, Jiang W, Zhang X, Qiu F, Gan Z, Cheng W, Zhang J, Guan S, Tang B, Huang Q, Wu X, Huang X, Jiang W, Hu Q, Lu M, Hua ZC.
    J Mol Med (Berl); 2013 Feb 15; 91(2):219-35. PubMed ID: 22948392
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  • 10. The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
    Raja SM, Chen S, Yue P, Acker TM, Lefkove B, Arbiser JL, Khuri FR, Sun SY.
    Mol Cancer Ther; 2008 Jul 15; 7(7):2212-23. PubMed ID: 18645030
    [Abstract] [Full Text] [Related]

  • 11. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S.
    Cancer Res; 2005 Mar 15; 65(6):2422-32. PubMed ID: 15781658
    [Abstract] [Full Text] [Related]

  • 12. The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
    Chiarini F, Del Sole M, Mongiorgi S, Gaboardi GC, Cappellini A, Mantovani I, Follo MY, McCubrey JA, Martelli AM.
    Leukemia; 2008 Jun 15; 22(6):1106-16. PubMed ID: 18385752
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  • 13. Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells.
    Su L, Liu G, Hao X, Zhong N, Zhong D, Liu X, Singhal S.
    Eur J Cancer; 2011 Nov 15; 47(16):2471-8. PubMed ID: 21726997
    [Abstract] [Full Text] [Related]

  • 14. Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.
    Liu X, Yue P, Schönthal AH, Khuri FR, Sun SY.
    Cancer Res; 2006 Dec 01; 66(23):11115-9. PubMed ID: 17145853
    [Abstract] [Full Text] [Related]

  • 15. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
    Zou W, Liu X, Yue P, Zhou Z, Sporn MB, Lotan R, Khuri FR, Sun SY.
    Cancer Res; 2004 Oct 15; 64(20):7570-8. PubMed ID: 15492284
    [Abstract] [Full Text] [Related]

  • 16. Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells.
    Lin Y, Liu X, Yue P, Benbrook DM, Berlin KD, Khuri FR, Sun SY.
    Mol Cancer Ther; 2008 Nov 15; 7(11):3556-65. PubMed ID: 19001438
    [Abstract] [Full Text] [Related]

  • 17. The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression.
    Lee J, Hwangbo C, Lee JJ, Seo J, Lee JH.
    Oncol Rep; 2010 Jan 15; 23(1):229-37. PubMed ID: 19956887
    [Abstract] [Full Text] [Related]

  • 18. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells.
    Kandasamy K, Srivastava RK.
    Cancer Res; 2002 Sep 01; 62(17):4929-37. PubMed ID: 12208743
    [Abstract] [Full Text] [Related]

  • 19. Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca2+/calmodulin signaling.
    Kaminskyy VO, Surova OV, Piskunova T, Zborovskaya IB, Tchevkina EM, Andera L, Zhivotovsky B.
    Cell Death Dis; 2013 Mar 07; 4(3):e522. PubMed ID: 23470529
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  • 20. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.
    Rosato RR, Almenara JA, Coe S, Grant S.
    Cancer Res; 2007 Oct 01; 67(19):9490-500. PubMed ID: 17909059
    [Abstract] [Full Text] [Related]


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