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156 related items for PubMed ID: 17604996

  • 1. Is the ubiquitin-proteasome system impaired in Huntington's disease?
    Ortega Z, Díaz-Hernández M, Lucas JJ.
    Cell Mol Life Sci; 2007 Sep; 64(17):2245-57. PubMed ID: 17604996
    [Abstract] [Full Text] [Related]

  • 2. Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease.
    Hunter JM, Lesort M, Johnson GV.
    J Neurosci Res; 2007 Jun; 85(8):1774-88. PubMed ID: 17455294
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain.
    Díaz-Hernández M, Valera AG, Morán MA, Gómez-Ramos P, Alvarez-Castelao B, Castaño JG, Hernández F, Lucas JJ.
    J Neurochem; 2006 Sep; 98(5):1585-96. PubMed ID: 16787406
    [Abstract] [Full Text] [Related]

  • 4. Testing the possible inhibition of proteasome by direct interaction with ubiquitylated and aggregated huntingtin.
    Valera AG, Díaz-Hernández M, Hernández F, Lucas JJ.
    Brain Res Bull; 2007 Apr 30; 72(2-3):121-3. PubMed ID: 17352935
    [Abstract] [Full Text] [Related]

  • 5. Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice.
    Wang J, Wang CE, Orr A, Tydlacka S, Li SH, Li XJ.
    J Cell Biol; 2008 Mar 24; 180(6):1177-89. PubMed ID: 18362179
    [Abstract] [Full Text] [Related]

  • 6. Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies.
    Schipper-Krom S, Juenemann K, Jansen AH, Wiemhoefer A, van den Nieuwendijk R, Smith DL, Hink MA, Bates GP, Overkleeft H, Ovaa H, Reits E.
    FEBS Lett; 2014 Jan 03; 588(1):151-9. PubMed ID: 24291262
    [Abstract] [Full Text] [Related]

  • 7. Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients.
    Seo H, Kim W, Isacson O.
    Hum Mol Genet; 2008 Oct 15; 17(20):3144-53. PubMed ID: 18640989
    [Abstract] [Full Text] [Related]

  • 8. Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin.
    Lin L, Jin Z, Tan H, Xu Q, Peng T, Li H.
    Brain Res; 2016 Jul 15; 1643():103-12. PubMed ID: 27107943
    [Abstract] [Full Text] [Related]

  • 9. Proteasome activator enhances survival of Huntington's disease neuronal model cells.
    Seo H, Sonntag KC, Kim W, Cattaneo E, Isacson O.
    PLoS One; 2007 Feb 28; 2(2):e238. PubMed ID: 17327906
    [Abstract] [Full Text] [Related]

  • 10. Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease.
    Hipp MS, Patel CN, Bersuker K, Riley BE, Kaiser SE, Shaler TA, Brandeis M, Kopito RR.
    J Cell Biol; 2012 Mar 05; 196(5):573-87. PubMed ID: 22371559
    [Abstract] [Full Text] [Related]

  • 11. Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments.
    Li X, Wang CE, Huang S, Xu X, Li XJ, Li H, Li S.
    Hum Mol Genet; 2010 Jun 15; 19(12):2445-55. PubMed ID: 20354076
    [Abstract] [Full Text] [Related]

  • 12. Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.
    Ortega Z, Díaz-Hernández M, Maynard CJ, Hernández F, Dantuma NP, Lucas JJ.
    J Neurosci; 2010 Mar 10; 30(10):3675-88. PubMed ID: 20220001
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of p38 Mitogen-Activated Protein Kinase Ameliorates HAP40 Depletion-Induced Toxicity and Proteasomal Defect in Huntington's Disease Model.
    Huang ZN, Chen JM, Huang LC, Fang YH, Her LS.
    Mol Neurobiol; 2021 Jun 10; 58(6):2704-2723. PubMed ID: 33492644
    [Abstract] [Full Text] [Related]

  • 14. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release.
    Jana NR, Zemskov EA, Wang Gh, Nukina N.
    Hum Mol Genet; 2001 May 01; 10(10):1049-59. PubMed ID: 11331615
    [Abstract] [Full Text] [Related]

  • 15. Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease.
    Mitra S, Tsvetkov AS, Finkbeiner S.
    J Biol Chem; 2009 Feb 13; 284(7):4398-403. PubMed ID: 19074152
    [Abstract] [Full Text] [Related]

  • 16. Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease.
    Liu Y, Hettinger CL, Zhang D, Rezvani K, Wang X, Wang H.
    J Neurochem; 2014 May 13; 129(3):539-47. PubMed ID: 24383989
    [Abstract] [Full Text] [Related]

  • 17. Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease.
    Lin JT, Chang WC, Chen HM, Lai HL, Chen CY, Tao MH, Chern Y.
    Mol Cell Biol; 2013 Mar 13; 33(5):1073-84. PubMed ID: 23275441
    [Abstract] [Full Text] [Related]

  • 18. The ubiquitin-proteasome reporter GFPu does not accumulate in neurons of the R6/2 transgenic mouse model of Huntington's disease.
    Bett JS, Cook C, Petrucelli L, Bates GP.
    PLoS One; 2009 Mar 13; 4(4):e5128. PubMed ID: 19352500
    [Abstract] [Full Text] [Related]

  • 19. Modest proteasomal inhibition by aberrant ubiquitin exacerbates aggregate formation in a Huntington disease mouse model.
    de Pril R, Hobo B, van Tijn P, Roos RA, van Leeuwen FW, Fischer DF.
    Mol Cell Neurosci; 2010 Mar 13; 43(3):281-6. PubMed ID: 20005957
    [Abstract] [Full Text] [Related]

  • 20. Huntington's disease: from pathology and genetics to potential therapies.
    Imarisio S, Carmichael J, Korolchuk V, Chen CW, Saiki S, Rose C, Krishna G, Davies JE, Ttofi E, Underwood BR, Rubinsztein DC.
    Biochem J; 2008 Jun 01; 412(2):191-209. PubMed ID: 18466116
    [Abstract] [Full Text] [Related]

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