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Journal Abstract Search

581 related items for PubMed ID: 17620347

  • 1. Prediction of human pharmacokinetics using physiologically based modeling: a retrospective analysis of 26 clinically tested drugs.
    De Buck SS, Sinha VK, Fenu LA, Nijsen MJ, Mackie CE, Gilissen RA.
    Drug Metab Dispos; 2007 Oct; 35(10):1766-80. PubMed ID: 17620347
    [Abstract] [Full Text] [Related]

  • 2. The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse compounds in rat using mechanism-based absorption, distribution, and metabolism prediction tools.
    De Buck SS, Sinha VK, Fenu LA, Gilissen RA, Mackie CE, Nijsen MJ.
    Drug Metab Dispos; 2007 Apr; 35(4):649-59. PubMed ID: 17267621
    [Abstract] [Full Text] [Related]

  • 3. Prediction of human pharmacokinetics--improving microsome-based predictions of hepatic metabolic clearance.
    Fagerholm U.
    J Pharm Pharmacol; 2007 Oct; 59(10):1427-31. PubMed ID: 17910819
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  • 4. Prediction of human pharmacokinetics--evaluation of methods for prediction of volume of distribution.
    Fagerholm U.
    J Pharm Pharmacol; 2007 Sep; 59(9):1181-90. PubMed ID: 17883888
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  • 5. Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.
    Fagerholm U.
    J Pharm Pharmacol; 2007 Jun; 59(6):803-28. PubMed ID: 17637173
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  • 6. Prediction of human oral pharmacokinetics using nonclinical data: examples involving four proprietary compounds.
    Fura A, Vyas V, Humphreys W, Chimalokonda A, Rodrigues D.
    Biopharm Drug Dispos; 2008 Nov; 29(8):455-68. PubMed ID: 18989850
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  • 7. Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.
    Hosea NA, Collard WT, Cole S, Maurer TS, Fang RX, Jones H, Kakar SM, Nakai Y, Smith BJ, Webster R, Beaumont K.
    J Clin Pharmacol; 2009 May; 49(5):513-33. PubMed ID: 19299532
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  • 8. Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.
    Poirier A, Funk C, Scherrmann JM, Lavé T.
    Mol Pharm; 2009 May; 6(6):1716-33. PubMed ID: 19739673
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  • 11. Prediction of human pharmacokinetics - renal metabolic and excretion clearance.
    Fagerholm U.
    J Pharm Pharmacol; 2007 Nov; 59(11):1463-71. PubMed ID: 17976256
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  • 12. Prediction of oral pharmacokinetics of cMet kinase inhibitors in humans: physiologically based pharmacokinetic model versus traditional one-compartment model.
    Yamazaki S, Skaptason J, Romero D, Vekich S, Jones HM, Tan W, Wilner KD, Koudriakova T.
    Drug Metab Dispos; 2011 Mar; 39(3):383-93. PubMed ID: 21098644
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  • 14. Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery.
    Lüpfert C, Reichel A.
    Chem Biodivers; 2005 Nov; 2(11):1462-86. PubMed ID: 17191947
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  • 15. Human pharmacokinetic prediction of UDP-glucuronosyltransferase substrates with an animal scale-up approach.
    Deguchi T, Watanabe N, Kurihara A, Igeta K, Ikenaga H, Fusegawa K, Suzuki N, Murata S, Hirouchi M, Furuta Y, Iwasaki M, Okazaki O, Izumi T.
    Drug Metab Dispos; 2011 May; 39(5):820-9. PubMed ID: 21282406
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  • 19. Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in rat plasma.
    Brightman FA, Leahy DE, Searle GE, Thomas S.
    Drug Metab Dispos; 2006 Jan; 34(1):84-93. PubMed ID: 16221757
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