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1105 related items for PubMed ID: 17636022

  • 1. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
    Sun Z, Zhang S, Chan JY, Zhang DD.
    Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
    [Abstract] [Full Text] [Related]

  • 2. Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.
    Giudice A, Arra C, Turco MC.
    Methods Mol Biol; 2010 Sep; 647():37-74. PubMed ID: 20694660
    [Abstract] [Full Text] [Related]

  • 3. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
    Kaspar JW, Niture SK, Jaiswal AK.
    J Cell Sci; 2012 Feb 15; 125(Pt 4):1027-38. PubMed ID: 22448038
    [Abstract] [Full Text] [Related]

  • 4. Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism.
    Velichkova M, Hasson T.
    Mol Cell Biol; 2005 Jun 15; 25(11):4501-13. PubMed ID: 15899855
    [Abstract] [Full Text] [Related]

  • 5. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
    Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M.
    Mol Cell Biol; 2004 Dec 15; 24(24):10941-53. PubMed ID: 15572695
    [Abstract] [Full Text] [Related]

  • 6. [Prothyomosin alpha interaction with KEAP1 doesn't lead to prothymosin alpha ubiquination and degradation].
    Mel'nikov SV, Evstaf'eva AG, Vartapetian AB.
    Mol Biol (Mosk); 2007 Dec 15; 41(5):868-75. PubMed ID: 18240569
    [Abstract] [Full Text] [Related]

  • 7. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
    Lo SC, Hannink M.
    Mol Cell Biol; 2006 Feb 15; 26(4):1235-44. PubMed ID: 16449638
    [Abstract] [Full Text] [Related]

  • 8. Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1.
    Nguyen T, Sherratt PJ, Nioi P, Yang CS, Pickett CB.
    J Biol Chem; 2005 Sep 16; 280(37):32485-92. PubMed ID: 16000310
    [Abstract] [Full Text] [Related]

  • 9. KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.
    Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD.
    Mol Cell Biol; 2011 May 16; 31(9):1800-11. PubMed ID: 21383067
    [Abstract] [Full Text] [Related]

  • 10. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
    Uruno A, Motohashi H.
    Nitric Oxide; 2011 Aug 01; 25(2):153-60. PubMed ID: 21385624
    [Abstract] [Full Text] [Related]

  • 11. A mutation of Keap1 found in breast cancer impairs its ability to repress Nrf2 activity.
    Nioi P, Nguyen T.
    Biochem Biophys Res Commun; 2007 Nov 03; 362(4):816-21. PubMed ID: 17822677
    [Abstract] [Full Text] [Related]

  • 12. The Keap1-Nrf2-antioxidant response element pathway: a review of its regulation by melatonin and the proteasome.
    Vriend J, Reiter RJ.
    Mol Cell Endocrinol; 2015 Feb 05; 401():213-20. PubMed ID: 25528518
    [Abstract] [Full Text] [Related]

  • 13. MicroRNA-200a controls Nrf2 activation by target Keap1 in hepatic stellate cell proliferation and fibrosis.
    Yang JJ, Tao H, Hu W, Liu LP, Shi KH, Deng ZY, Li J.
    Cell Signal; 2014 Nov 05; 26(11):2381-9. PubMed ID: 25049078
    [Abstract] [Full Text] [Related]

  • 14. The gasotransmitter hydrogen sulfide induces nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between cys-226 and cys-613.
    Hourihan JM, Kenna JG, Hayes JD.
    Antioxid Redox Signal; 2013 Aug 10; 19(5):465-81. PubMed ID: 23145493
    [Abstract] [Full Text] [Related]

  • 15. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
    Furukawa M, Xiong Y.
    Mol Cell Biol; 2005 Jan 10; 25(1):162-71. PubMed ID: 15601839
    [Abstract] [Full Text] [Related]

  • 16. Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
    Su C, Zhang P, Song X, Shi Q, Fu J, Xia X, Bai H, Hu L, Xu D, Song E, Song Y.
    Chem Res Toxicol; 2015 Apr 20; 28(4):765-74. PubMed ID: 25742418
    [Abstract] [Full Text] [Related]

  • 17. Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.
    Katoh Y, Iida K, Kang MI, Kobayashi A, Mizukami M, Tong KI, McMahon M, Hayes JD, Itoh K, Yamamoto M.
    Arch Biochem Biophys; 2005 Jan 15; 433(2):342-50. PubMed ID: 15581590
    [Abstract] [Full Text] [Related]

  • 18. Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.
    Ohnuma T, Nakayama S, Anan E, Nishiyama T, Ogura K, Hiratsuka A.
    Toxicol Appl Pharmacol; 2010 Apr 01; 244(1):27-36. PubMed ID: 20026152
    [Abstract] [Full Text] [Related]

  • 19. Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.
    Taguchi K, Motohashi H, Yamamoto M.
    Genes Cells; 2011 Feb 01; 16(2):123-40. PubMed ID: 21251164
    [Abstract] [Full Text] [Related]

  • 20. The role of Nrf2 in oxidative stress-induced endothelial injuries.
    Chen B, Lu Y, Chen Y, Cheng J.
    J Endocrinol; 2015 Jun 01; 225(3):R83-99. PubMed ID: 25918130
    [Abstract] [Full Text] [Related]

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