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336 related items for PubMed ID: 17640631

  • 1. Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells.
    Merrell MA, Wakchoure S, Lehenkari PP, Harris KW, Selander KS.
    Eur J Pharmacol; 2007 Sep 10; 570(1-3):27-37. PubMed ID: 17640631
    [Abstract] [Full Text] [Related]

  • 2. Differential effects of Ca(2+) on bisphosphonate-induced growth inhibition in breast cancer and mesothelioma cells.
    Merrell MA, Wakchoure S, Ilvesaro JM, Zinn K, Gehrs B, Lehenkari PP, Harris KW, Selander KS.
    Eur J Pharmacol; 2007 Mar 15; 559(1):21-31. PubMed ID: 17214981
    [Abstract] [Full Text] [Related]

  • 3. Bisphosphonates inhibit the growth of mesothelioma cells in vitro and in vivo.
    Wakchoure S, Merrell MA, Aldrich W, Millender-Swain T, Harris KW, Triozzi P, Selander KS.
    Clin Cancer Res; 2006 May 01; 12(9):2862-8. PubMed ID: 16675582
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases.
    Dunford JE, Rogers MJ, Ebetino FH, Phipps RJ, Coxon FP.
    J Bone Miner Res; 2006 May 01; 21(5):684-94. PubMed ID: 16734383
    [Abstract] [Full Text] [Related]

  • 5. Induction of apoptosis in breast cancer cells by apomine is mediated by caspase and p38 mitogen activated protein kinase activation.
    Lowe LC, Senaratne SG, Colston KW.
    Biochem Biophys Res Commun; 2005 Apr 08; 329(2):772-9. PubMed ID: 15737653
    [Abstract] [Full Text] [Related]

  • 6. Pamidronate inhibits antiapoptotic bcl-2 expression through inhibition of the mevalonate pathway in prostate cancer PC-3 cells.
    Iguchi K, Tatsuda Y, Usui S, Hirano K.
    Eur J Pharmacol; 2010 Sep 01; 641(1):35-40. PubMed ID: 20519142
    [Abstract] [Full Text] [Related]

  • 7. Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells.
    Oades GM, Senaratne SG, Clarke IA, Kirby RS, Colston KW.
    J Urol; 2003 Jul 01; 170(1):246-52. PubMed ID: 12796698
    [Abstract] [Full Text] [Related]

  • 8. The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro.
    Mitrofan LM, Pelkonen J, Mönkkönen J.
    Bone; 2009 Dec 01; 45(6):1153-60. PubMed ID: 19699819
    [Abstract] [Full Text] [Related]

  • 9. The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
    Shipman CM, Croucher PI, Russell RG, Helfrich MH, Rogers MJ.
    Cancer Res; 1998 Dec 01; 58(23):5294-7. PubMed ID: 9850051
    [Abstract] [Full Text] [Related]

  • 10. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells.
    Räikkönen J, Mönkkönen H, Auriola S, Mönkkönen J.
    Biochem Pharmacol; 2010 Mar 01; 79(5):777-83. PubMed ID: 19819230
    [Abstract] [Full Text] [Related]

  • 11. Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
    Virtanen SS, Väänänen HK, Härkönen PL, Lakkakorpi PT.
    Cancer Res; 2002 May 01; 62(9):2708-14. PubMed ID: 11980672
    [Abstract] [Full Text] [Related]

  • 12. Magnolol elicits activation of the extracellular signal-regulated kinase pathway by inducing p27KIP1-mediated G2/M-phase cell cycle arrest in human urinary bladder cancer 5637 cells.
    Lee SJ, Cho YH, Park K, Kim EJ, Jung KH, Park SS, Kim WJ, Moon SK.
    Biochem Pharmacol; 2008 Jun 15; 75(12):2289-300. PubMed ID: 18468578
    [Abstract] [Full Text] [Related]

  • 13. Efficacy of a nitrogen-containing bisphosphonate, minodronate, in conjunction with a p38 mitogen activated protein kinase inhibitor or doxorubicin against malignant bone tumor cells.
    Kubo T, Shimose S, Matsuo T, Sakai A, Ochi M.
    Cancer Chemother Pharmacol; 2008 Jun 15; 62(1):111-6. PubMed ID: 17874104
    [Abstract] [Full Text] [Related]

  • 14. Berberine, a natural cholesterol reducing product, exerts antitumor cytostatic/cytotoxic effects independently from the mevalonate pathway.
    Issat T, Jakóbisiak M, Golab J.
    Oncol Rep; 2006 Dec 15; 16(6):1273-6. PubMed ID: 17089049
    [Abstract] [Full Text] [Related]

  • 15. Tamoxifen-induced activation of p21Waf1/Cip1 gene transcription is mediated by Early Growth Response-1 protein through the JNK and p38 MAP kinase/Elk-1 cascades in MDA-MB-361 breast carcinoma cells.
    Kim CG, Choi BH, Son SW, Yi SJ, Shin SY, Lee YH.
    Cell Signal; 2007 Jun 15; 19(6):1290-300. PubMed ID: 17307334
    [Abstract] [Full Text] [Related]

  • 16. Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway.
    Song JX, Ren JY, Chen H.
    J Cardiovasc Pharmacol; 2011 Feb 15; 57(2):213-22. PubMed ID: 21052011
    [Abstract] [Full Text] [Related]

  • 17. Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kappaB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase.
    Lee SJ, Kim HM, Cho YH, Park K, Kim EJ, Jung KH, Kim CH, Kim WJ, Moon SK.
    Oncol Rep; 2007 Sep 15; 18(3):729-36. PubMed ID: 17671727
    [Abstract] [Full Text] [Related]

  • 18. Protoapigenone, a novel flavonoid, induces apoptosis in human prostate cancer cells through activation of p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase 1/2.
    Chang HL, Wu YC, Su JH, Yeh YT, Yuan SS.
    J Pharmacol Exp Ther; 2008 Jun 15; 325(3):841-9. PubMed ID: 18337475
    [Abstract] [Full Text] [Related]

  • 19. Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells.
    Iguchi K, Nakano T, Usui S, Hirano K.
    Cancer Lett; 2006 Jun 18; 237(2):223-33. PubMed ID: 16019130
    [Abstract] [Full Text] [Related]

  • 20. Genistein-induced apoptosis of human breast cancer MCF-7 cells involves calpain-caspase and apoptosis signaling kinase 1-p38 mitogen-activated protein kinase activation cascades.
    Shim HY, Park JH, Paik HD, Nah SY, Kim DS, Han YS.
    Anticancer Drugs; 2007 Jul 18; 18(6):649-57. PubMed ID: 17762393
    [Abstract] [Full Text] [Related]

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