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302 related items for PubMed ID: 17653853

  • 1. Indole-3-carbinol-induced modulation of NF-kappaB signalling is breast cancer cell-specific and does not correlate with cell death.
    Moiseeva EP, Heukers R.
    Breast Cancer Res Treat; 2008 Jun; 109(3):451-62. PubMed ID: 17653853
    [Abstract] [Full Text] [Related]

  • 2. EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells.
    Moiseeva EP, Heukers R, Manson MM.
    Carcinogenesis; 2007 Feb; 28(2):435-45. PubMed ID: 16956907
    [Abstract] [Full Text] [Related]

  • 3. Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D environment.
    Moiseeva EP, Fox LH, Howells LM, Temple LA, Manson MM.
    Apoptosis; 2006 May; 11(5):799-812. PubMed ID: 16532375
    [Abstract] [Full Text] [Related]

  • 4. Inactivation of akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells.
    Rahman KM, Li Y, Sarkar FH.
    Nutr Cancer; 2004 May; 48(1):84-94. PubMed ID: 15203382
    [Abstract] [Full Text] [Related]

  • 5. Indole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line.
    Howells LM, Gallacher-Horley B, Houghton CE, Manson MM, Hudson EA.
    Mol Cancer Ther; 2002 Nov; 1(13):1161-72. PubMed ID: 12479697
    [Abstract] [Full Text] [Related]

  • 6. Indole-3-carbinol suppresses NF-κB activity and stimulates the p53 pathway in pre-B acute lymphoblastic leukemia cells.
    Safa M, Tavasoli B, Manafi R, Kiani F, Kashiri M, Ebrahimi S, Kazemi A.
    Tumour Biol; 2015 May; 36(5):3919-30. PubMed ID: 25589462
    [Abstract] [Full Text] [Related]

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  • 8. Inhibition of nuclear translocation of nuclear factor-{kappa}B contributes to 3,3'-diindolylmethane-induced apoptosis in breast cancer cells.
    Rahman KW, Sarkar FH.
    Cancer Res; 2005 Jan 01; 65(1):364-71. PubMed ID: 15665315
    [Abstract] [Full Text] [Related]

  • 9. Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells.
    Rahman KM, Aranha O, Glazyrin A, Chinni SR, Sarkar FH.
    Oncogene; 2000 Nov 23; 19(50):5764-71. PubMed ID: 11126363
    [Abstract] [Full Text] [Related]

  • 10. Indole-3-Carbinol (I3C) enhances the sensitivity of murine breast adenocarcinoma cells to doxorubicin (DOX) through inhibition of NF-κβ, blocking angiogenesis and regulation of mitochondrial apoptotic pathway.
    Hajra S, Patra AR, Basu A, Saha P, Bhattacharya S.
    Chem Biol Interact; 2018 Jun 25; 290():19-36. PubMed ID: 29775573
    [Abstract] [Full Text] [Related]

  • 11. Indole-3-carbinol enhances the resolution of rat liver fibrosis and stimulates hepatic stellate cell apoptosis by blocking the inhibitor of κB kinase α/inhibitor of κB-α/nuclear factor-κB pathway.
    Ping J, Gao AM, Qin HQ, Wei XN, Bai J, Liu L, Li XH, Li RW, Ao Y, Wang H.
    J Pharmacol Exp Ther; 2011 Nov 25; 339(2):694-703. PubMed ID: 21862660
    [Abstract] [Full Text] [Related]

  • 12. Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model.
    Rahman KM, Sarkar FH, Banerjee S, Wang Z, Liao DJ, Hong X, Sarkar NH.
    Mol Cancer Ther; 2006 Nov 25; 5(11):2747-56. PubMed ID: 17121921
    [Abstract] [Full Text] [Related]

  • 13. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.
    Chinni SR, Li Y, Upadhyay S, Koppolu PK, Sarkar FH.
    Oncogene; 2001 May 24; 20(23):2927-36. PubMed ID: 11420705
    [Abstract] [Full Text] [Related]

  • 14. Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
    Takada Y, Andreeff M, Aggarwal BB.
    Blood; 2005 Jul 15; 106(2):641-9. PubMed ID: 15811958
    [Abstract] [Full Text] [Related]

  • 15. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 15; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 16. Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
    Aronchik I, Chen T, Durkin KA, Horwitz MS, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.
    Mol Carcinog; 2012 Nov 15; 51(11):881-94. PubMed ID: 22012859
    [Abstract] [Full Text] [Related]

  • 17. Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo.
    Matsumoto G, Namekawa J, Muta M, Nakamura T, Bando H, Tohyama K, Toi M, Umezawa K.
    Clin Cancer Res; 2005 Feb 01; 11(3):1287-93. PubMed ID: 15709200
    [Abstract] [Full Text] [Related]

  • 18. Direct inhibition of elastase activity by indole-3-carbinol triggers a CD40-TRAF regulatory cascade that disrupts NF-kappaB transcriptional activity in human breast cancer cells.
    Aronchik I, Bjeldanes LF, Firestone GL.
    Cancer Res; 2010 Jun 15; 70(12):4961-71. PubMed ID: 20530686
    [Abstract] [Full Text] [Related]

  • 19. AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells.
    Rabi T, Huwiler A, Zangemeister-Wittke U.
    Mol Carcinog; 2014 Jul 15; 53(7):578-88. PubMed ID: 23475563
    [Abstract] [Full Text] [Related]

  • 20. Ganoderic acids suppress growth and angiogenesis by modulating the NF-κB signaling pathway in breast cancer cells.
    Li F, Wang Y, Wang X, Li J, Cui H, Niu M.
    Int J Clin Pharmacol Ther; 2012 Oct 15; 50(10):712-21. PubMed ID: 22762853
    [Abstract] [Full Text] [Related]

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