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458 related items for PubMed ID: 17657593

  • 1. Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression.
    Prawan A, Keum YS, Khor TO, Yu S, Nair S, Li W, Hu L, Kong AN.
    Pharm Res; 2008 Apr; 25(4):836-44. PubMed ID: 17657593
    [Abstract] [Full Text] [Related]

  • 2. Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates.
    Saw CL, Cintrón M, Wu TY, Guo Y, Huang Y, Jeong WS, Kong AN.
    Biopharm Drug Dispos; 2011 Jul; 32(5):289-300. PubMed ID: 21656528
    [Abstract] [Full Text] [Related]

  • 3. Nuclear factor E2-related factor 2-mediated induction of NAD(P)H:quinone oxidoreductase 1 by 3,5-dimethoxy-trans-stilbene.
    Park EJ, Min HY, Park HJ, Chung HJ, Ahn YH, Pyee JH, Lee SK.
    J Pharmacol Sci; 2011 Jul; 116(1):89-96. PubMed ID: 21512304
    [Abstract] [Full Text] [Related]

  • 4. Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes.
    La Marca M, Beffy P, Della Croce C, Gervasi PG, Iori R, Puccinelli E, Longo V.
    Food Chem Toxicol; 2012 Aug; 50(8):2822-30. PubMed ID: 22664424
    [Abstract] [Full Text] [Related]

  • 5. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
    Xu C, Yuan X, Pan Z, Shen G, Kim JH, Yu S, Khor TO, Li W, Ma J, Kong AN.
    Mol Cancer Ther; 2006 Aug; 5(8):1918-26. PubMed ID: 16928811
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells.
    Keum YS, Yu S, Chang PP, Yuan X, Kim JH, Xu C, Han J, Agarwal A, Kong AN.
    Cancer Res; 2006 Sep 01; 66(17):8804-13. PubMed ID: 16951197
    [Abstract] [Full Text] [Related]

  • 7. Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.
    Lee HH, Park SA, Almazari I, Kim EH, Na HK, Surh YJ.
    Arch Biochem Biophys; 2010 Sep 01; 501(1):142-50. PubMed ID: 20558128
    [Abstract] [Full Text] [Related]

  • 8. Differential expression and stability of endogenous nuclear factor E2-related factor 2 (Nrf2) by natural chemopreventive compounds in HepG2 human hepatoma cells.
    Jeong WS, Keum YS, Chen C, Jain MR, Shen G, Kim JH, Li W, Kong AN.
    J Biochem Mol Biol; 2005 Mar 31; 38(2):167-76. PubMed ID: 15826493
    [Abstract] [Full Text] [Related]

  • 9. Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.
    Higgins LG, Cavin C, Itoh K, Yamamoto M, Hayes JD.
    Toxicol Appl Pharmacol; 2008 Feb 01; 226(3):328-37. PubMed ID: 18028974
    [Abstract] [Full Text] [Related]

  • 10. In vivo imaging of antioxidant response element activity during liver regeneration after partial hepatectomy.
    Alizai PH, Bertram L, Fragoulis A, Wruck CJ, Kroy DC, Klinge U, Neumann UP, Schmeding M.
    J Surg Res; 2016 Dec 01; 206(2):525-535. PubMed ID: 27884351
    [Abstract] [Full Text] [Related]

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  • 12. Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2.
    Shin JW, Ohnishi K, Murakami A, Lee JS, Kundu JK, Na HK, Ohigashi H, Surh YJ.
    Cancer Prev Res (Phila); 2011 Jun 01; 4(6):860-70. PubMed ID: 21367956
    [Abstract] [Full Text] [Related]

  • 13. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
    Rojo AI, Medina-Campos ON, Rada P, Zúñiga-Toalá A, López-Gazcón A, Espada S, Pedraza-Chaverri J, Cuadrado A.
    Free Radic Biol Med; 2012 Jan 15; 52(2):473-87. PubMed ID: 22142471
    [Abstract] [Full Text] [Related]

  • 14. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW.
    Mol Med; 2001 Feb 15; 7(2):135-45. PubMed ID: 11471548
    [Abstract] [Full Text] [Related]

  • 15. Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim.
    Velmurugan K, Alam J, McCord JM, Pugazhenthi S.
    Free Radic Biol Med; 2009 Feb 01; 46(3):430-40. PubMed ID: 19056485
    [Abstract] [Full Text] [Related]

  • 16. tBHQ-induced HO-1 expression is mediated by calcium through regulation of Nrf2 binding to enhancer and polymerase II to promoter region of HO-1.
    Cheung KL, Yu S, Pan Z, Ma J, Wu TY, Kong AN.
    Chem Res Toxicol; 2011 May 16; 24(5):670-6. PubMed ID: 21443188
    [Abstract] [Full Text] [Related]

  • 17. Guggulsterone induces heme oxygenase-1 expression through activation of Nrf2 in human mammary epithelial cells: PTEN as a putative target.
    Almazari I, Park JM, Park SA, Suh JY, Na HK, Cha YN, Surh YJ.
    Carcinogenesis; 2012 Feb 16; 33(2):368-76. PubMed ID: 22095074
    [Abstract] [Full Text] [Related]

  • 18. Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling.
    Prawan A, Saw CL, Khor TO, Keum YS, Yu S, Hu L, Kong AN.
    Chem Biol Interact; 2009 May 15; 179(2-3):202-11. PubMed ID: 19159619
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells.
    Li H, Wood JT, Whitten KM, Vadivel SK, Seng S, Makriyannis A, Avraham HK.
    Br J Pharmacol; 2013 Oct 15; 170(3):489-505. PubMed ID: 23347118
    [Abstract] [Full Text] [Related]

  • 20. Total intracellular accumulation levels of dietary isothiocyanates determine their activity in elevation of cellular glutathione and induction of Phase 2 detoxification enzymes.
    Ye L, Zhang Y.
    Carcinogenesis; 2001 Dec 15; 22(12):1987-92. PubMed ID: 11751429
    [Abstract] [Full Text] [Related]

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