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Journal Abstract Search


755 related items for PubMed ID: 17658508

  • 1. Effect of ramosetron on conditioned emotional stress-induced colonic dysfunction as a model of irritable bowel syndrome in rats.
    Funatsu T, Takeuchi A, Hirata T, Keto Y, Akuzawa S, Sasamata M.
    Eur J Pharmacol; 2007 Nov 14; 573(1-3):190-5. PubMed ID: 17658508
    [Abstract] [Full Text] [Related]

  • 2. Effects of serotonin 5-HT(3) receptor antagonists on CRF-induced abnormal colonic water transport and defecation in rats.
    Hirata T, Keto Y, Nakata M, Takeuchi A, Funatsu T, Akuzawa S, Sasamata M, Miyata K.
    Eur J Pharmacol; 2008 Jun 10; 587(1-3):281-4. PubMed ID: 18456254
    [Abstract] [Full Text] [Related]

  • 3. Pharmacological profile of ramosetron, a novel therapeutic agent for IBS.
    Hirata T, Funatsu T, Keto Y, Nakata M, Sasamata M.
    Inflammopharmacology; 2007 Feb 10; 15(1):5-9. PubMed ID: 17323187
    [Abstract] [Full Text] [Related]

  • 4. Evaluation of the pharmacological profile of ramosetron, a novel therapeutic agent for irritable bowel syndrome.
    Hirata T, Keto Y, Funatsu T, Akuzawa S, Sasamata M.
    J Pharmacol Sci; 2007 Jul 10; 104(3):263-73. PubMed ID: 17652911
    [Abstract] [Full Text] [Related]

  • 5. Effects of serotonin 5-HT3 receptor antagonists on stress-induced colonic hyperalgesia and diarrhoea in rats: a comparative study with opioid receptor agonists, a muscarinic receptor antagonist and a synthetic polymer.
    Hirata T, Keto Y, Nakata M, Takeuchi A, Funatsu T, Akuzawa S, Sasamata M, Miyata K.
    Neurogastroenterol Motil; 2008 May 10; 20(5):557-65. PubMed ID: 18221252
    [Abstract] [Full Text] [Related]

  • 6. Restraint stress stimulates colonic motility via central corticotropin-releasing factor and peripheral 5-HT3 receptors in conscious rats.
    Nakade Y, Fukuda H, Iwa M, Tsukamoto K, Yanagi H, Yamamura T, Mantyh C, Pappas TN, Takahashi T.
    Am J Physiol Gastrointest Liver Physiol; 2007 Apr 10; 292(4):G1037-44. PubMed ID: 17158256
    [Abstract] [Full Text] [Related]

  • 7. Inhibitory effects of ramosetron, a potent and selective 5-HT3-receptor antagonist, on conditioned fear stress-induced abnormal defecation and normal defecation in rats: comparative studies with antidiarrheal and spasmolytic agents.
    Hirata T, Funatsu T, Keto Y, Akuzawa S, Sasamata M, Miyata K.
    J Pharmacol Sci; 2008 Feb 10; 106(2):264-70. PubMed ID: 18296863
    [Abstract] [Full Text] [Related]

  • 8. Pharmacological properties of 3-amino-5,6,7,8-tetrahydro-2-[4-[4-(quinolin-2-yl)piperazin-1-yl]butyl]quinazolin-4(3H)-one (TZB-30878), a novel therapeutic agent for diarrhea-predominant irritable bowel syndrome (IBS) and its effects on an experimental IBS model.
    Tamaoki S, Yamauchi Y, Nakano Y, Sakano S, Asagarasu A, Sato M.
    J Pharmacol Exp Ther; 2007 Sep 10; 322(3):1315-23. PubMed ID: 17540858
    [Abstract] [Full Text] [Related]

  • 9. Effect of FK1052, a potent 5-hydroxytryptamine3 and 5-hydroxytryptamine4 receptor dual antagonist, on colonic function in vivo.
    Kadowaki M, Nagakura Y, Tomoi M, Mori J, Kohsaka M.
    J Pharmacol Exp Ther; 1993 Jul 10; 266(1):74-80. PubMed ID: 8331576
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of phosphodiesterase type 4 decreases stress-induced defecation in rats and mice.
    Barone FC, Barton ME, White RF, Legos JJ, Kikkawa H, Shimamura M, Kuratani K, Kinoshita M.
    Pharmacology; 2008 Jul 10; 81(1):11-7. PubMed ID: 17726343
    [Abstract] [Full Text] [Related]

  • 11. Gender-related differences in slowing colonic transit by a 5-HT3 antagonist in subjects with diarrhea-predominant irritable bowel syndrome.
    Viramontes BE, Camilleri M, McKinzie S, Pardi DS, Burton D, Thomforde GM.
    Am J Gastroenterol; 2001 Sep 10; 96(9):2671-6. PubMed ID: 11569693
    [Abstract] [Full Text] [Related]

  • 12. Wood creosote prevents CRF-induced motility via 5-HT3 receptors in proximal and 5-HT4 receptors in distal colon in rats.
    Ataka K, Kuge T, Fujino K, Takahashi T, Fujimiya M.
    Auton Neurosci; 2007 May 30; 133(2):136-45. PubMed ID: 17182287
    [Abstract] [Full Text] [Related]

  • 13. Inhibitory effect of ramosetron on corticotropin releasing factor- and soybean oil-induced delays in gastric emptying in rats.
    Hirata T, Keto Y, Yamano M, Yokoyama T, Sengoku T, Seki N.
    J Gastroenterol Hepatol; 2012 Sep 30; 27(9):1505-11. PubMed ID: 22554268
    [Abstract] [Full Text] [Related]

  • 14. Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: differential effects of acute psychological and physical stressors.
    O'Malley D, Dinan TG, Cryan JF.
    Peptides; 2010 Apr 30; 31(4):662-70. PubMed ID: 20096320
    [Abstract] [Full Text] [Related]

  • 15. Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-releasing factor receptor type-1 upregulation in the rat intestine and IBS-like gut dysfunction.
    Vicario M, Alonso C, Guilarte M, Serra J, Martínez C, González-Castro AM, Lobo B, Antolín M, Andreu AL, García-Arumí E, Casellas M, Saperas E, Malagelada JR, Azpiroz F, Santos J.
    Psychoneuroendocrinology; 2012 Jan 30; 37(1):65-77. PubMed ID: 21641728
    [Abstract] [Full Text] [Related]

  • 16. Effects of neonatal maternal separation on neurochemical and sensory response to colonic distension in a rat model of irritable bowel syndrome.
    Ren TH, Wu J, Yew D, Ziea E, Lao L, Leung WK, Berman B, Hu PJ, Sung JJ.
    Am J Physiol Gastrointest Liver Physiol; 2007 Mar 30; 292(3):G849-56. PubMed ID: 17110521
    [Abstract] [Full Text] [Related]

  • 17. Effect of YNS-15P, a new alpha-2 adrenoceptor antagonist, on stress-stimulated colonic propulsion in rats.
    Yamamoto O, Niida H, Tajima K, Shirouchi Y, Kyotani Y, Ueda F, Kise M, Kimura K.
    J Pharmacol Exp Ther; 1998 Nov 30; 287(2):691-6. PubMed ID: 9808698
    [Abstract] [Full Text] [Related]

  • 18. Selective corticotropin-releasing factor 1 receptor antagonist E2508 reduces restraint stress-induced defecation and visceral pain in rat models.
    Taguchi R, Shikata K, Furuya Y, Hirakawa T, Ino M, Shin K, Shibata H.
    Psychoneuroendocrinology; 2017 Jan 30; 75():110-115. PubMed ID: 27810704
    [Abstract] [Full Text] [Related]

  • 19. 5-HT3 receptor antagonists. 3. Quinoline derivatives which may be effective in the therapy of irritable bowel syndrome.
    Kishibayashi N, Miwa Y, Hayashi H, Ishii A, Ichikawa S, Nonaka H, Yokoyama T, Suzuki F.
    J Med Chem; 1993 Oct 29; 36(22):3286-92. PubMed ID: 8230119
    [Abstract] [Full Text] [Related]

  • 20. Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome.
    Andresen V, Camilleri M, Busciglio IA, Grudell A, Burton D, McKinzie S, Foxx-Orenstein A, Kurtz CB, Sharma V, Johnston JM, Currie MG, Zinsmeister AR.
    Gastroenterology; 2007 Sep 29; 133(3):761-8. PubMed ID: 17854590
    [Abstract] [Full Text] [Related]


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