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Journal Abstract Search

433 related items for PubMed ID: 17660383

  • 21. 2-(Naphthalene-1-yl)-6-pyrrolidinyl-4-quinazolinone inhibits skin cancer M21 cell proliferation through aberrant expression of microtubules and the cell cycle.
    Wu YC, Hour MJ, Leung WC, Wu CY, Liu WZ, Chang YH, Lee HZ.
    J Pharmacol Exp Ther; 2011 Sep; 338(3):942-51. PubMed ID: 21652781
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  • 22. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
    Jiang JD, Davis AS, Middleton K, Ling YH, Perez-Soler R, Holland JF, Bekesi JG.
    Cancer Res; 1998 Dec 01; 58(23):5389-95. PubMed ID: 9850070
    [Abstract] [Full Text] [Related]

  • 23. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ.
    ChemMedChem; 2012 Apr 01; 7(4):680-93. PubMed ID: 22311585
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  • 24. Identification and characterization of A-105972, an antineoplastic agent.
    Wu-Wong JR, Alder JD, Alder L, Burns DJ, Han EK, Credo B, Tahir SK, Dayton BD, Ewing PJ, Chiou WJ.
    Cancer Res; 2001 Feb 15; 61(4):1486-92. PubMed ID: 11245455
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  • 25. Novel antitumor indenoindole derivatives targeting DNA and topoisomerase II.
    Bal C, Baldeyrou B, Moz F, Lansiaux A, Colson P, Kraus-Berthier L, Léonce S, Pierré A, Boussard MF, Rousseau A, Wierzbicki M, Bailly C.
    Biochem Pharmacol; 2004 Nov 15; 68(10):1911-22. PubMed ID: 15476662
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  • 26. BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.
    Lee FY, Borzilleri R, Fairchild CR, Kim SH, Long BH, Reventos-Suarez C, Vite GD, Rose WC, Kramer RA.
    Clin Cancer Res; 2001 May 15; 7(5):1429-37. PubMed ID: 11350914
    [Abstract] [Full Text] [Related]

  • 27. MPT0B169, a new tubulin inhibitor, inhibits cell growth and induces G2/M arrest in nonresistant and paclitaxel-resistant cancer cells.
    Lee WH, Liu HE, Chang JY, Liou JP, Huang HM.
    Pharmacology; 2013 May 15; 92(1-2):90-8. PubMed ID: 23949011
    [Abstract] [Full Text] [Related]

  • 28. Preclinical antitumor activity of the oral platinum analog satraplatin.
    Wosikowski K, Lamphere L, Unteregger G, Jung V, Kaplan F, Xu JP, Rattel B, Caligiuri M.
    Cancer Chemother Pharmacol; 2007 Sep 15; 60(4):589-600. PubMed ID: 17541592
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  • 29. Marchantin C, a novel microtubule inhibitor from liverwort with anti-tumor activity both in vivo and in vitro.
    Shi YQ, Zhu CJ, Yuan HQ, Li BQ, Gao J, Qu XJ, Sun B, Cheng YN, Li S, Li X, Lou HX.
    Cancer Lett; 2009 Apr 18; 276(2):160-70. PubMed ID: 19095349
    [Abstract] [Full Text] [Related]

  • 30. WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers.
    Hsiao CJ, Li TK, Chan YL, Hsin LW, Liao CH, Lee CH, Lyu PC, Guh JH.
    Biochem Pharmacol; 2008 Feb 15; 75(4):847-56. PubMed ID: 18035333
    [Abstract] [Full Text] [Related]

  • 31. [Effects of CPUY013, a novel Topo I inhibitor, on human gastric adenocarcinoma BGC823 cells in vitro and in vivo].
    Ji YB, Zhou JH, Zuo MX, You QD.
    Yao Xue Xue Bao; 2008 Aug 15; 43(8):811-8. PubMed ID: 18956773
    [Abstract] [Full Text] [Related]

  • 32. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 33. YHHU0895, a novel synthetic small-molecule microtubule-destabilizing agent, effectively overcomes P-glycoprotein-mediated tumor multidrug resistance.
    Zhao H, Quan H, Xie C, Xu Y, Xie F, Hu Y, Lou L.
    Cancer Lett; 2012 Jan 01; 314(1):54-62. PubMed ID: 21982683
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  • 34. Characterization of the hollow fiber assay for the determination of microtubule disruption in vivo.
    Suggitt M, Swaine DJ, Pettit GR, Bibby MC.
    Clin Cancer Res; 2004 Oct 01; 10(19):6677-85. PubMed ID: 15475458
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  • 35. Identification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole.
    Mooberry SL, Weiderhold KN, Dakshanamurthy S, Hamel E, Banner EJ, Kharlamova A, Hempel J, Gupton JT, Brown ML.
    Mol Pharmacol; 2007 Jul 01; 72(1):132-40. PubMed ID: 17456786
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  • 36. Multidrug resistance-associated protein-overexpressing teniposide-resistant human lymphomas undergo apoptosis by a tubulin-binding agent.
    Aneja R, Liu M, Yates C, Gao J, Dong X, Zhou B, Vangapandu SN, Zhou J, Joshi HC.
    Cancer Res; 2008 Mar 01; 68(5):1495-503. PubMed ID: 18316614
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  • 37. Novel 2-methoxyestradiol analogues with antitumor activity.
    Tinley TL, Leal RM, Randall-Hlubek DA, Cessac JW, Wilkens LR, Rao PN, Mooberry SL.
    Cancer Res; 2003 Apr 01; 63(7):1538-49. PubMed ID: 12670902
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  • 38. Human urine extract CDA-2 induces apoptosis of myelodysplastic syndrome-derived MUTZ-1 cells through the PI3K/Akt signaling pathway in a caspase-3-dependent manner.
    Huang J, Yang M, Liu H, Jin J.
    Acta Pharmacol Sin; 2008 Aug 01; 29(8):951-64. PubMed ID: 18664328
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  • 39. KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells.
    Shin KD, Yoon YJ, Kang YR, Son KH, Kim HM, Kwon BM, Han DC.
    Biochem Pharmacol; 2008 Jan 15; 75(2):383-94. PubMed ID: 17915194
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  • 40. Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo.
    O'Reilly T, Wartmann M, Brueggen J, Allegrini PR, Floersheimer A, Maira M, McSheehy PM.
    Cancer Chemother Pharmacol; 2008 Nov 15; 62(6):1045-54. PubMed ID: 18301895
    [Abstract] [Full Text] [Related]

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