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Journal Abstract Search

218 related items for PubMed ID: 17664350

  • 1. Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.
    Léon C, Eckly A, Hechler B, Aleil B, Freund M, Ravanat C, Jourdain M, Nonne C, Weber J, Tiedt R, Gratacap MP, Severin S, Cazenave JP, Lanza F, Skoda R, Gachet C.
    Blood; 2007 Nov 01; 110(9):3183-91. PubMed ID: 17664350
    [Abstract] [Full Text] [Related]

  • 2. Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation.
    Eckly A, Strassel C, Freund M, Cazenave JP, Lanza F, Gachet C, Léon C.
    Blood; 2009 Apr 02; 113(14):3182-9. PubMed ID: 18984861
    [Abstract] [Full Text] [Related]

  • 3. Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice.
    Eckly A, Rinckel JY, Laeuffer P, Cazenave JP, Lanza F, Gachet C, Léon C.
    J Thromb Haemost; 2010 Oct 02; 8(10):2243-51. PubMed ID: 20695978
    [Abstract] [Full Text] [Related]

  • 4. Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD.
    Léon C, Evert K, Dombrowski F, Pertuy F, Eckly A, Laeuffer P, Gachet C, Greinacher A.
    Blood; 2012 Apr 05; 119(14):3333-41. PubMed ID: 22234693
    [Abstract] [Full Text] [Related]

  • 5. Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets.
    Pertuy F, Eckly A, Weber J, Proamer F, Rinckel JY, Lanza F, Gachet C, Léon C.
    Blood; 2014 Feb 20; 123(8):1261-9. PubMed ID: 24243973
    [Abstract] [Full Text] [Related]

  • 6. Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9-related disease.
    Pal K, Nowak R, Billington N, Liu R, Ghosh A, Sellers JR, Fowler VM.
    Blood; 2020 May 21; 135(21):1887-1898. PubMed ID: 32315395
    [Abstract] [Full Text] [Related]

  • 7. Altered cytoskeleton organization in platelets from patients with MYH9-related disease.
    Canobbio I, Noris P, Pecci A, Balduini A, Balduini CL, Torti M.
    J Thromb Haemost; 2005 May 21; 3(5):1026-35. PubMed ID: 15869600
    [Abstract] [Full Text] [Related]

  • 8. Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia.
    Spinler KR, Shin JW, Lambert MP, Discher DE.
    Blood; 2015 Jan 15; 125(3):525-33. PubMed ID: 25395423
    [Abstract] [Full Text] [Related]

  • 9. Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A.
    Zhang Y, Conti MA, Malide D, Dong F, Wang A, Shmist YA, Liu C, Zerfas P, Daniels MP, Chan CC, Kozin E, Kachar B, Kelley MJ, Kopp JB, Adelstein RS.
    Blood; 2012 Jan 05; 119(1):238-50. PubMed ID: 21908426
    [Abstract] [Full Text] [Related]

  • 10. The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition.
    Chen Y, Boukour S, Milloud R, Favier R, Saposnik B, Schlegel N, Nurden A, Raslova H, Vainchenker W, Balland M, Nurden P, Debili N.
    J Thromb Haemost; 2013 Dec 05; 11(12):2163-75. PubMed ID: 24165359
    [Abstract] [Full Text] [Related]

  • 11. Defective VWF secretion due to expression of MYH9-RD E1841K mutant in endothelial cells disrupts hemostasis.
    Cao Y, Sun Y, Deng Y, Wei G, Liu J, Jin S, Dong C, Kang X, Huo Y, Zhang J, Luo J.
    Blood Adv; 2022 Aug 09; 6(15):4537-4552. PubMed ID: 35764499
    [Abstract] [Full Text] [Related]

  • 12. Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability.
    Suzuki N, Kunishima S, Ikejiri M, Maruyama S, Sone M, Takagi A, Ikawa M, Okabe M, Kojima T, Saito H, Naoe T, Matsushita T.
    PLoS One; 2013 Aug 09; 8(8):e71187. PubMed ID: 23976996
    [Abstract] [Full Text] [Related]

  • 13. Myosin light chain 6 (Myl6) interacts with kindlin-3 and is required to support integrin αIIbβ3 activation in platelets in mice.
    Xu Z, Zhou Y, Yu H, Chen X, Ma YQ.
    J Thromb Haemost; 2024 Jul 09; 22(7):2009-2017. PubMed ID: 38266679
    [Abstract] [Full Text] [Related]

  • 14. Megakaryocytes of patients with MYH9-related thrombocytopenia present an altered proplatelet formation.
    Pecci A, Malara A, Badalucco S, Bozzi V, Torti M, Balduini CL, Balduini A.
    Thromb Haemost; 2009 Jul 09; 102(1):90-6. PubMed ID: 19572073
    [Abstract] [Full Text] [Related]

  • 15. Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis.
    Pleines I, Hagedorn I, Gupta S, May F, Chakarova L, van Hengel J, Offermanns S, Krohne G, Kleinschnitz C, Brakebusch C, Nieswandt B.
    Blood; 2012 Jan 26; 119(4):1054-63. PubMed ID: 22045984
    [Abstract] [Full Text] [Related]

  • 16. Megakaryocyte and platelet abnormalities in a patient with a W33C mutation in the conserved SH3-like domain of myosin heavy chain IIA.
    Kahr WH, Savoia A, Pluthero FG, Li L, Christensen H, De Rocco D, Traivaree C, Butchart SE, Curtin J, Stollar EJ, Forman-Kay JD, Blanchette VS.
    Thromb Haemost; 2009 Dec 26; 102(6):1241-50. PubMed ID: 19967157
    [Abstract] [Full Text] [Related]

  • 17. Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth.
    Ono A, Westein E, Hsiao S, Nesbitt WS, Hamilton JR, Schoenwaelder SM, Jackson SP.
    Blood; 2008 Jul 01; 112(1):90-9. PubMed ID: 18310501
    [Abstract] [Full Text] [Related]

  • 18. Mutations responsible for MYH9-related thrombocytopenia impair SDF-1-driven migration of megakaryoblastic cells.
    Pecci A, Bozzi V, Panza E, Barozzi S, Gruppi C, Seri M, Balduini CL.
    Thromb Haemost; 2011 Oct 01; 106(4):693-704. PubMed ID: 21833445
    [Abstract] [Full Text] [Related]

  • 19. Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: relevance for MYH9-related disease.
    Marini M, Bruschi M, Pecci A, Romagnoli R, Musante L, Candiano G, Ghiggeri GM, Balduini C, Seri M, Ravazzolo R.
    Int J Mol Med; 2006 May 01; 17(5):729-36. PubMed ID: 16596254
    [Abstract] [Full Text] [Related]

  • 20. Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes.
    Heath KE, Campos-Barros A, Toren A, Rozenfeld-Granot G, Carlsson LE, Savige J, Denison JC, Gregory MC, White JG, Barker DF, Greinacher A, Epstein CJ, Glucksman MJ, Martignetti JA.
    Am J Hum Genet; 2001 Nov 01; 69(5):1033-45. PubMed ID: 11590545
    [Abstract] [Full Text] [Related]

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