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319 related items for PubMed ID: 17666455

  • 1. Hyperforin--a key constituent of St. John's wort specifically activates TRPC6 channels.
    Leuner K, Kazanski V, Müller M, Essin K, Henke B, Gollasch M, Harteneck C, Müller WE.
    FASEB J; 2007 Dec; 21(14):4101-11. PubMed ID: 17666455
    [Abstract] [Full Text] [Related]

  • 2. [Cellular and molecular effects of the antidepressant hyperforin on brain cells: Review of the literature].
    Bouron A, Lorrain E.
    Encephale; 2014 Apr; 40(2):108-13. PubMed ID: 23816060
    [Abstract] [Full Text] [Related]

  • 3. Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca(2+) -permeable TRPC6 channels.
    Leuner K, Li W, Amaral MD, Rudolph S, Calfa G, Schuwald AM, Harteneck C, Inoue T, Pozzo-Miller L.
    Hippocampus; 2013 Jan; 23(1):40-52. PubMed ID: 22815087
    [Abstract] [Full Text] [Related]

  • 4. Protonophore properties of hyperforin are essential for its pharmacological activity.
    Sell TS, Belkacemi T, Flockerzi V, Beck A.
    Sci Rep; 2014 Dec 16; 4():7500. PubMed ID: 25511254
    [Abstract] [Full Text] [Related]

  • 5. The TRPC6 channel activator hyperforin induces the release of zinc and calcium from mitochondria.
    Tu P, Gibon J, Bouron A.
    J Neurochem; 2010 Jan 16; 112(1):204-13. PubMed ID: 19845832
    [Abstract] [Full Text] [Related]

  • 6. TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling.
    Heiser JH, Schuwald AM, Sillani G, Ye L, Müller WE, Leuner K.
    J Neurochem; 2013 Nov 16; 127(3):303-13. PubMed ID: 23875811
    [Abstract] [Full Text] [Related]

  • 7. Simple 2,4-diacylphloroglucinols as classic transient receptor potential-6 activators--identification of a novel pharmacophore.
    Leuner K, Heiser JH, Derksen S, Mladenov MI, Fehske CJ, Schubert R, Gollasch M, Schneider G, Harteneck C, Chatterjee SS, Müller WE.
    Mol Pharmacol; 2010 Mar 16; 77(3):368-77. PubMed ID: 20008516
    [Abstract] [Full Text] [Related]

  • 8. Role of hyperforin in the pharmacological activities of St. John's Wort.
    Zanoli P.
    CNS Drug Rev; 2004 Mar 16; 10(3):203-18. PubMed ID: 15492771
    [Abstract] [Full Text] [Related]

  • 9. Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway.
    Zhou C, Tabb MM, Sadatrafiei A, Grün F, Sun A, Blumberg B.
    J Clin Immunol; 2004 Nov 16; 24(6):623-36. PubMed ID: 15622447
    [Abstract] [Full Text] [Related]

  • 10. Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line.
    Tian R, Koyabu N, Morimoto S, Shoyama Y, Ohtani H, Sawada Y.
    Drug Metab Dispos; 2005 Apr 16; 33(4):547-54. PubMed ID: 15640377
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of synaptosomal uptake of 3H-L-glutamate and 3H-GABA by hyperforin, a major constituent of St. John's Wort: the role of amiloride sensitive sodium conductive pathways.
    Wonnemann M, Singer A, Müller WE.
    Neuropsychopharmacology; 2000 Aug 16; 23(2):188-97. PubMed ID: 10882845
    [Abstract] [Full Text] [Related]

  • 12. Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line.
    Menegazzi M, Novelli M, Beffy P, D'Aleo V, Tedeschi E, Lupi R, Zoratti E, Marchetti P, Suzuki H, Masiello P.
    Int J Biochem Cell Biol; 2008 Aug 16; 40(8):1509-21. PubMed ID: 18226577
    [Abstract] [Full Text] [Related]

  • 13. Current St John's wort research from mode of action to clinical efficacy.
    Müller WE.
    Pharmacol Res; 2003 Feb 16; 47(2):101-9. PubMed ID: 12543057
    [Abstract] [Full Text] [Related]

  • 14. NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort.
    Kumar V, Mdzinarishvili A, Kiewert C, Abbruscato T, Bickel U, van der Schyf CJ, Klein J.
    J Pharmacol Sci; 2006 Sep 16; 102(1):47-54. PubMed ID: 16936454
    [Abstract] [Full Text] [Related]

  • 15. Hyperforin--antidepressant activity by a novel mechanism of action.
    Müller WE, Singer A, Wonnemann M.
    Pharmacopsychiatry; 2001 Jul 16; 34 Suppl 1():S98-102. PubMed ID: 11518085
    [Abstract] [Full Text] [Related]

  • 16. Dual modulation of striatal acetylcholine release by hyperforin, a constituent of St. John's wort.
    Buchholzer ML, Dvorak C, Chatterjee SS, Klein J.
    J Pharmacol Exp Ther; 2002 May 16; 301(2):714-9. PubMed ID: 11961077
    [Abstract] [Full Text] [Related]

  • 17. Store-depletion and hyperforin activate distinct types of Ca(2+)-conducting channels in cortical neurons.
    Gibon J, Tu P, Bouron A.
    Cell Calcium; 2010 Jun 16; 47(6):538-43. PubMed ID: 20621761
    [Abstract] [Full Text] [Related]

  • 18. Stimulation of hippocampal acetylcholine release by hyperforin, a constituent of St. John's Wort.
    Kiewert C, Buchholzer ML, Hartmann J, Chatterjee SS, Klein J.
    Neurosci Lett; 2004 Jul 08; 364(3):195-8. PubMed ID: 15196674
    [Abstract] [Full Text] [Related]

  • 19. Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation.
    Lin Y, Zhang JC, Fu J, Chen F, Wang J, Wu ZL, Yuan SY.
    J Cereb Blood Flow Metab; 2013 Feb 08; 33(2):253-62. PubMed ID: 23149561
    [Abstract] [Full Text] [Related]

  • 20. [Hypericin and hyperforin: bioactive components of St. John's Wort (Hypericum perforatum). Their isolation, analysis and study of physiological effect].
    Vacek J, Klejdus B, Kubán V.
    Ceska Slov Farm; 2007 Apr 08; 56(2):62-6. PubMed ID: 17619301
    [Abstract] [Full Text] [Related]

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