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Journal Abstract Search

288 related items for PubMed ID: 17670976

  • 1. The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection.
    Corti C, Battaglia G, Molinaro G, Riozzi B, Pittaluga A, Corsi M, Mugnaini M, Nicoletti F, Bruno V.
    J Neurosci; 2007 Aug 01; 27(31):8297-308. PubMed ID: 17670976
    [Abstract] [Full Text] [Related]

  • 2. Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective.
    Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F.
    Mol Pharmacol; 2011 Mar 01; 79(3):618-26. PubMed ID: 21159998
    [Abstract] [Full Text] [Related]

  • 3. Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis.
    Battaglia G, Riozzi B, Bucci D, Di Menna L, Molinaro G, Pallottino S, Nicoletti F, Bruno V.
    Neurobiol Dis; 2015 Feb 01; 74():126-36. PubMed ID: 25434487
    [Abstract] [Full Text] [Related]

  • 4. Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice.
    Linden AM, Shannon H, Baez M, Yu JL, Koester A, Schoepp DD.
    Psychopharmacology (Berl); 2005 Apr 01; 179(1):284-91. PubMed ID: 15619115
    [Abstract] [Full Text] [Related]

  • 5. Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039).
    Fell MJ, Svensson KA, Johnson BG, Schoepp DD.
    J Pharmacol Exp Ther; 2008 Jul 01; 326(1):209-17. PubMed ID: 18424625
    [Abstract] [Full Text] [Related]

  • 6. Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice.
    Molinaro G, Traficante A, Riozzi B, Di Menna L, Curto M, Pallottino S, Nicoletti F, Bruno V, Battaglia G.
    Mol Pharmacol; 2009 Aug 01; 76(2):379-87. PubMed ID: 19439499
    [Abstract] [Full Text] [Related]

  • 7. mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists.
    Zammataro M, Chiechio S, Montana MC, Traficante A, Copani A, Nicoletti F, Gereau RW.
    Mol Pain; 2011 Jan 14; 7():6. PubMed ID: 21235748
    [Abstract] [Full Text] [Related]

  • 8. Differentiating the roles of mGlu2 and mGlu3 receptors using LY541850, an mGlu2 agonist/mGlu3 antagonist.
    Hanna L, Ceolin L, Lucas S, Monn J, Johnson B, Collingridge G, Bortolotto Z, Lodge D.
    Neuropharmacology; 2013 Mar 14; 66():114-21. PubMed ID: 22445601
    [Abstract] [Full Text] [Related]

  • 9. Regulation of group II metabotropic glutamate receptors by G protein-coupled receptor kinases: mGlu2 receptors are resistant to homologous desensitization.
    Iacovelli L, Molinaro G, Battaglia G, Motolese M, Di Menna L, Alfiero M, Blahos J, Matrisciano F, Corsi M, Corti C, Bruno V, De Blasi A, Nicoletti F.
    Mol Pharmacol; 2009 Apr 14; 75(4):991-1003. PubMed ID: 19164443
    [Abstract] [Full Text] [Related]

  • 10. Pharmacological profiling of native group II metabotropic glutamate receptors in primary cortical neuronal cultures using a FLIPR.
    Sanger H, Hanna L, Colvin EM, Grubisha O, Ursu D, Heinz BA, Findlay JD, Vivier RG, Sher E, Lodge D, Monn JA, Broad LM.
    Neuropharmacology; 2013 Mar 14; 66():264-73. PubMed ID: 22659090
    [Abstract] [Full Text] [Related]

  • 11. Selective activation of either mGlu2 or mGlu3 receptors can induce LTD in the amygdala.
    Lucas SJ, Bortolotto ZA, Collingridge GL, Lodge D.
    Neuropharmacology; 2013 Mar 14; 66():196-201. PubMed ID: 22531751
    [Abstract] [Full Text] [Related]

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  • 13. Immuno-pharmacological characterization of group II metabotropic glutamate receptors controlling glutamate exocytosis in mouse cortex and spinal cord.
    Olivero G, Bonfiglio T, Vergassola M, Usai C, Riozzi B, Battaglia G, Nicoletti F, Pittaluga A.
    Br J Pharmacol; 2017 Dec 14; 174(24):4785-4796. PubMed ID: 28967122
    [Abstract] [Full Text] [Related]

  • 14. Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death.
    Bruno V, Battaglia G, Ksiazek I, van der Putten H, Catania MV, Giuffrida R, Lukic S, Leonhardt T, Inderbitzin W, Gasparini F, Kuhn R, Hampson DR, Nicoletti F, Flor PJ.
    J Neurosci; 2000 Sep 01; 20(17):6413-20. PubMed ID: 10964947
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo[3.1.0] hexane-2,6-dicarboxylic acid (LY354740): identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptors.
    Monn JA, Valli MJ, Massey SM, Hansen MM, Kress TJ, Wepsiec JP, Harkness AR, Grutsch JL, Wright RA, Johnson BG, Andis SL, Kingston A, Tomlinson R, Lewis R, Griffey KR, Tizzano JP, Schoepp DD.
    J Med Chem; 1999 Mar 25; 42(6):1027-40. PubMed ID: 10090786
    [Abstract] [Full Text] [Related]

  • 16. A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity.
    Galici R, Echemendia NG, Rodriguez AL, Conn PJ.
    J Pharmacol Exp Ther; 2005 Dec 25; 315(3):1181-7. PubMed ID: 16123306
    [Abstract] [Full Text] [Related]

  • 17. Activation of mGlu3 receptors stimulates the production of GDNF in striatal neurons.
    Battaglia G, Molinaro G, Riozzi B, Storto M, Busceti CL, Spinsanti P, Bucci D, Di Liberto V, Mudò G, Corti C, Corsi M, Nicoletti F, Belluardo N, Bruno V.
    PLoS One; 2009 Aug 12; 4(8):e6591. PubMed ID: 19672295
    [Abstract] [Full Text] [Related]

  • 18. Selective activation of group-II metabotropic glutamate receptors is protective against excitotoxic neuronal death.
    Battaglia G, Bruno V, Ngomba RT, Di Grezia R, Copani A, Nicoletti F.
    Eur J Pharmacol; 1998 Sep 04; 356(2-3):271-4. PubMed ID: 9774259
    [Abstract] [Full Text] [Related]

  • 19. Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells.
    Bruno V, Wroblewska B, Wroblewski JT, Fiore L, Nicoletti F.
    Neuroscience; 1998 Aug 04; 85(3):751-7. PubMed ID: 9639269
    [Abstract] [Full Text] [Related]

  • 20. Astroglial mGlu3 receptors promote alpha-secretase-mediated amyloid precursor protein cleavage.
    Durand D, Carniglia L, Beauquis J, Caruso C, Saravia F, Lasaga M.
    Neuropharmacology; 2014 Apr 04; 79():180-9. PubMed ID: 24291464
    [Abstract] [Full Text] [Related]

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