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612 related items for PubMed ID: 17675586

  • 1. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
    Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV.
    Mol Pharmacol; 2007 Nov; 72(5):1137-45. PubMed ID: 17675586
    [Abstract] [Full Text] [Related]

  • 2. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
    Duan Z, Bradner JE, Greenberg E, Levine R, Foster R, Mahoney J, Seiden MV.
    Clin Cancer Res; 2006 Nov 15; 12(22):6844-52. PubMed ID: 17121906
    [Abstract] [Full Text] [Related]

  • 3. Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer.
    Duan Z, Foster R, Bell DA, Mahoney J, Wolak K, Vaidya A, Hampel C, Lee H, Seiden MV.
    Clin Cancer Res; 2006 Sep 01; 12(17):5055-63. PubMed ID: 16951221
    [Abstract] [Full Text] [Related]

  • 4. Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells.
    Behera R, Kumar V, Lohite K, Karnik S, Kundu GC.
    Carcinogenesis; 2010 Feb 01; 31(2):192-200. PubMed ID: 19926637
    [Abstract] [Full Text] [Related]

  • 5. Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis.
    Kusaba M, Nakao K, Goto T, Nishimura D, Kawashimo H, Shibata H, Motoyoshi Y, Taura N, Ichikawa T, Hamasaki K, Eguchi K.
    J Hepatol; 2007 Oct 01; 47(4):546-55. PubMed ID: 17602782
    [Abstract] [Full Text] [Related]

  • 6. Naphtho[1,2-b]furan-4,5-dione disrupts Janus kinase-2 and induces apoptosis in breast cancer MDA-MB-231 cells.
    Lin KL, Su JC, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR.
    Toxicol In Vitro; 2010 Jun 01; 24(4):1158-67. PubMed ID: 20197088
    [Abstract] [Full Text] [Related]

  • 7. Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation.
    Zhao W, Zhang T, Qu B, Wu X, Zhu X, Meng F, Gu Y, Shu Y, Shen Y, Sun Y, Xu Q.
    Anticancer Drugs; 2011 Jan 01; 22(1):79-88. PubMed ID: 20881478
    [Abstract] [Full Text] [Related]

  • 8. Contribution of STAT3 to the activation of survivin by GM-CSF in CD34+ cell lines.
    Gu L, Chiang KY, Zhu N, Findley HW, Zhou M.
    Exp Hematol; 2007 Jun 01; 35(6):957-66. PubMed ID: 17533050
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line.
    Gariboldi MB, Ravizza R, Molteni R, Osella D, Gabano E, Monti E.
    Cancer Lett; 2007 Dec 18; 258(2):181-8. PubMed ID: 17920763
    [Abstract] [Full Text] [Related]

  • 10. Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells.
    Gritsko T, Williams A, Turkson J, Kaneko S, Bowman T, Huang M, Nam S, Eweis I, Diaz N, Sullivan D, Yoder S, Enkemann S, Eschrich S, Lee JH, Beam CA, Cheng J, Minton S, Muro-Cacho CA, Jove R.
    Clin Cancer Res; 2006 Jan 01; 12(1):11-9. PubMed ID: 16397018
    [Abstract] [Full Text] [Related]

  • 11. 17-hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells.
    Wang Y, Ma X, Yan S, Shen S, Zhu H, Gu Y, Wang H, Qin G, Yu Q.
    Cancer Res; 2009 Sep 15; 69(18):7302-10. PubMed ID: 19706767
    [Abstract] [Full Text] [Related]

  • 12. Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.
    Kreis S, Munz GA, Haan S, Heinrich PC, Behrmann I.
    Mol Cancer Res; 2007 Dec 15; 5(12):1331-41. PubMed ID: 18171991
    [Abstract] [Full Text] [Related]

  • 13. Epidermal growth factor-induced ovarian carcinoma cell migration is associated with JAK2/STAT3 signals and changes in the abundance and localization of alpha6beta1 integrin.
    Colomiere M, Findlay J, Ackland L, Ahmed N.
    Int J Biochem Cell Biol; 2009 May 15; 41(5):1034-45. PubMed ID: 18930836
    [Abstract] [Full Text] [Related]

  • 14. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.
    J Pharmacol Exp Ther; 2010 Jul 15; 334(1):285-93. PubMed ID: 20378717
    [Abstract] [Full Text] [Related]

  • 15. Nuclear protein IkappaB-zeta inhibits the activity of STAT3.
    Wu Z, Zhang X, Yang J, Wu G, Zhang Y, Yuan Y, Jin C, Chang Z, Wang J, Yang X, He F.
    Biochem Biophys Res Commun; 2009 Sep 18; 387(2):348-52. PubMed ID: 19595668
    [Abstract] [Full Text] [Related]

  • 16. Effects of a JAK inhibitor, AG490, on proliferation and apoptosis of human nasopharyngeal carcinoma cell line CNE-2Z.
    Wu MH, Chen XY, Cai KR.
    Ai Zheng; 2009 Jan 18; 28(1):24-8. PubMed ID: 19448411
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin.
    Zhou J, Ong CN, Hur GM, Shen HM.
    Biochem Pharmacol; 2010 May 01; 79(9):1242-50. PubMed ID: 20026083
    [Abstract] [Full Text] [Related]

  • 18. A small molecule compound inhibits AKT pathway in ovarian cancer cell lines.
    Tang HJ, Jin X, Wang S, Yang D, Cao Y, Chen J, Gossett DR, Lin J.
    Gynecol Oncol; 2006 Feb 01; 100(2):308-17. PubMed ID: 16209885
    [Abstract] [Full Text] [Related]

  • 19. Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.
    Pedranzini L, Dechow T, Berishaj M, Comenzo R, Zhou P, Azare J, Bornmann W, Bromberg J.
    Cancer Res; 2006 Oct 01; 66(19):9714-21. PubMed ID: 17018630
    [Abstract] [Full Text] [Related]

  • 20. A Ras homologue member I directly inhibits signal transducers and activators of transcription 3 translocation and activity in human breast and ovarian cancer cells.
    Nishimoto A, Yu Y, Lu Z, Mao X, Ren Z, Watowich SS, Mills GB, Liao WS, Chen X, Bast RC, Luo RZ.
    Cancer Res; 2005 Aug 01; 65(15):6701-10. PubMed ID: 16061651
    [Abstract] [Full Text] [Related]

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