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160 related items for PubMed ID: 17678437

  • 1. N-methyl-N'-nitro-N-nitrosoguanidine activates multiple cell death mechanisms in human fibroblasts.
    Lee MW, Kim WJ, Beardsley DI, Brown KD.
    DNA Cell Biol; 2007 Sep; 26(9):683-94. PubMed ID: 17678437
    [Abstract] [Full Text] [Related]

  • 2. The monofunctional alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways.
    Kim WJ, Beardsley DI, Adamson AW, Brown KD.
    Toxicol Appl Pharmacol; 2005 Jan 01; 202(1):84-98. PubMed ID: 15589979
    [Abstract] [Full Text] [Related]

  • 3. The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.
    Vidal B, Parra M, Jardí M, Saito S, Appella E, Muñoz-Cánoves P.
    Thromb Haemost; 2005 Mar 01; 93(3):584-91. PubMed ID: 15735814
    [Abstract] [Full Text] [Related]

  • 4. ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation.
    Adamson AW, Kim WJ, Shangary S, Baskaran R, Brown KD.
    J Biol Chem; 2002 Oct 11; 277(41):38222-9. PubMed ID: 12151394
    [Abstract] [Full Text] [Related]

  • 5. Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.
    Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, Susin SA.
    Mol Cell Biol; 2007 Jul 11; 27(13):4844-62. PubMed ID: 17470554
    [Abstract] [Full Text] [Related]

  • 6. Non-apoptogenic killing of hela cervical carcinoma cells after short exposure to the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
    Wesierska-Gadek J, Gueorguieva M, Schloffer D, Uhl M, Wojciechowski J.
    J Cell Biochem; 2003 Aug 15; 89(6):1222-34. PubMed ID: 12898520
    [Abstract] [Full Text] [Related]

  • 7. Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity.
    Bai P, Hegedus C, Erdélyi K, Szabó E, Bakondi E, Gergely S, Szabó C, Virág L.
    Toxicol Lett; 2007 May 15; 170(3):203-13. PubMed ID: 17428624
    [Abstract] [Full Text] [Related]

  • 8. AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.
    Baritaud M, Cabon L, Delavallée L, Galán-Malo P, Gilles ME, Brunelle-Navas MN, Susin SA.
    Cell Death Dis; 2012 Sep 13; 3(9):e390. PubMed ID: 22972376
    [Abstract] [Full Text] [Related]

  • 9. Oxidative stress initiates DNA damager MNNG-induced poly(ADP-ribose)polymerase-1-dependent parthanatos cell death.
    Chiu LY, Ho FM, Shiah SG, Chang Y, Lin WW.
    Biochem Pharmacol; 2011 Feb 01; 81(3):459-70. PubMed ID: 21056551
    [Abstract] [Full Text] [Related]

  • 10. Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage.
    Affar el B, Shah RG, Dallaire AK, Castonguay V, Shah GM.
    Proc Natl Acad Sci U S A; 2002 Jan 08; 99(1):245-50. PubMed ID: 11756665
    [Abstract] [Full Text] [Related]

  • 11. Ataxia-telangiectasia-mutated-dependent activation of Ku in human fibroblasts exposed to hydrogen peroxide.
    Lee JH, Kim KH, Morio T, Kim H.
    Ann N Y Acad Sci; 2006 Dec 08; 1091():76-82. PubMed ID: 17341604
    [Abstract] [Full Text] [Related]

  • 12. MNNG-induced cell death is controlled by interactions between PARP-1, poly(ADP-ribose) glycohydrolase, and XRCC1.
    Keil C, Gröbe T, Oei SL.
    J Biol Chem; 2006 Nov 10; 281(45):34394-405. PubMed ID: 16963444
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair.
    Bryant HE, Helleday T.
    Nucleic Acids Res; 2006 Nov 10; 34(6):1685-91. PubMed ID: 16556909
    [Abstract] [Full Text] [Related]

  • 14. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.
    Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL.
    Science; 2002 Jul 12; 297(5579):259-63. PubMed ID: 12114629
    [Abstract] [Full Text] [Related]

  • 15. Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage.
    Liu X, Luo X, Shi Y, Zhu GD, Penning T, Giranda VL, Luo Y.
    Cancer Biol Ther; 2008 Jun 12; 7(6):934-41. PubMed ID: 18376143
    [Abstract] [Full Text] [Related]

  • 16. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2.
    Adamson AW, Beardsley DI, Kim WJ, Gao Y, Baskaran R, Brown KD.
    Mol Biol Cell; 2005 Mar 12; 16(3):1513-26. PubMed ID: 15647386
    [Abstract] [Full Text] [Related]

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  • 18. MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea.
    McDaid JR, Loughery J, Dunne P, Boyer JC, Downes CS, Farber RA, Walsh CP.
    Br J Cancer; 2009 Aug 04; 101(3):441-51. PubMed ID: 19623177
    [Abstract] [Full Text] [Related]

  • 19. PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca(2+)-permeable AMPA receptors.
    Gerace E, Masi A, Resta F, Felici R, Landucci E, Mello T, Pellegrini-Giampietro DE, Mannaioni G, Moroni F.
    Neurobiol Dis; 2014 Oct 04; 70():43-52. PubMed ID: 24954469
    [Abstract] [Full Text] [Related]

  • 20. Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.
    Pogrebniak A, Schemainda I, Pelka-Fleischer R, Nüssler V, Hasmann M.
    Eur J Med Res; 2003 Oct 22; 8(10):438-50. PubMed ID: 14594650
    [Abstract] [Full Text] [Related]

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