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Journal Abstract Search

140 related items for PubMed ID: 17699773

  • 1. Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized.
    Padrón D, Sato M, Shay JW, Gazdar AF, Minna JD, Roth MG.
    Cancer Res; 2007 Aug 15; 67(16):7695-702. PubMed ID: 17699773
    [Abstract] [Full Text] [Related]

  • 2. Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins.
    Shimamura T, Lowell AM, Engelman JA, Shapiro GI.
    Cancer Res; 2005 Jul 15; 65(14):6401-8. PubMed ID: 16024644
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  • 3. Mutant epidermal growth factor receptor undergoes less protein degradation due to diminished binding to c-Cbl.
    Hosaka T, Inoue F, Ando K, Ishida H, Kusumoto S, Sugiyama T, Shirai T, Okuda K, Hirose T, Ohnishi T, Horichi N, Saijo N, Adachi M, Nakadate T, Kuroki T, Ohmori T.
    Anticancer Res; 2007 Jul 15; 27(4B):2253-63. PubMed ID: 17695511
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  • 4. Association with HSP90 inhibits Cbl-mediated down-regulation of mutant epidermal growth factor receptors.
    Yang S, Qu S, Perez-Tores M, Sawai A, Rosen N, Solit DB, Arteaga CL.
    Cancer Res; 2006 Jul 15; 66(14):6990-7. PubMed ID: 16849543
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  • 5. Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.
    Shtiegman K, Kochupurakkal BS, Zwang Y, Pines G, Starr A, Vexler A, Citri A, Katz M, Lavi S, Ben-Basat Y, Benjamin S, Corso S, Gan J, Yosef RB, Giordano S, Yarden Y.
    Oncogene; 2007 Oct 25; 26(49):6968-78. PubMed ID: 17486068
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  • 7. Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma.
    Das AK, Chen BP, Story MD, Sato M, Minna JD, Chen DJ, Nirodi CS.
    Cancer Res; 2007 Jun 01; 67(11):5267-74. PubMed ID: 17545606
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  • 8. The Cbl RING finger C-terminal flank controls epidermal growth factor receptor fate downstream of receptor ubiquitination.
    Visser GD, Lill NL.
    Exp Cell Res; 2005 Dec 10; 311(2):281-93. PubMed ID: 16246327
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  • 10. Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel.
    Sawai A, Chandarlapaty S, Greulich H, Gonen M, Ye Q, Arteaga CL, Sellers W, Rosen N, Solit DB.
    Cancer Res; 2008 Jan 15; 68(2):589-96. PubMed ID: 18199556
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  • 11. [Ubiquitination-mediated degradation of epidermal growth factor receptor].
    Xiu X, Lü ZM.
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2005 Feb 15; 27(1):120-7. PubMed ID: 15782507
    [Abstract] [Full Text] [Related]

  • 12. Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis.
    Furukawa M, Nagatomo I, Kumagai T, Yamadori T, Takahashi R, Yoshimura M, Yoneda T, Takeda Y, Goya S, Matsuoka H, Kijima T, Yoshida M, Osaki T, Tachibana I, Greene MI, Kawase I.
    DNA Cell Biol; 2007 Mar 15; 26(3):178-85. PubMed ID: 17417946
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  • 13. The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor.
    Smith CJ, Berry DM, McGlade CJ.
    J Cell Sci; 2013 Mar 15; 126(Pt 6):1366-80. PubMed ID: 23418353
    [Abstract] [Full Text] [Related]

  • 14. The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor.
    Kobayashi N, Toyooka S, Soh J, Yamamoto H, Dote H, Kawasaki K, Otani H, Kubo T, Jida M, Ueno T, Ando M, Ogino A, Kiura K, Miyoshi S.
    Lung Cancer; 2012 Feb 15; 75(2):161-6. PubMed ID: 21767894
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  • 17. EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes.
    Grandal MV, Zandi R, Pedersen MW, Willumsen BM, van Deurs B, Poulsen HS.
    Carcinogenesis; 2007 Jul 15; 28(7):1408-17. PubMed ID: 17372273
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  • 19. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways.
    Sordella R, Bell DW, Haber DA, Settleman J.
    Science; 2004 Aug 20; 305(5687):1163-7. PubMed ID: 15284455
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  • 20. Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor.
    Oksvold MP, Thien CB, Widerberg J, Chantry A, Huitfeldt HS, Langdon WY.
    Oncogene; 2003 Nov 20; 22(52):8509-18. PubMed ID: 14627991
    [Abstract] [Full Text] [Related]

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