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446 related items for PubMed ID: 17704828

  • 1. The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products.
    Fischer L, Hornig M, Pergola C, Meindl N, Franke L, Tanrikulu Y, Dodt G, Schneider G, Steinhilber D, Werz O.
    Br J Pharmacol; 2007 Oct; 152(4):471-80. PubMed ID: 17704828
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors.
    Fischer L, Szellas D, Rådmark O, Steinhilber D, Werz O.
    FASEB J; 2003 May; 17(8):949-51. PubMed ID: 12670876
    [Abstract] [Full Text] [Related]

  • 3. BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly.
    Garscha U, Voelker S, Pace S, Gerstmeier J, Emini B, Liening S, Rossi A, Weinigel C, Rummler S, Schubert US, Scriba GK, Çelikoğlu E, Çalışkan B, Banoglu E, Sautebin L, Werz O.
    Biochem Pharmacol; 2016 Nov 01; 119():17-26. PubMed ID: 27592027
    [Abstract] [Full Text] [Related]

  • 4. An experimental cell-based model for studying the cell biology and molecular pharmacology of 5-lipoxygenase-activating protein in leukotriene biosynthesis.
    Gerstmeier J, Weinigel C, Barz D, Werz O, Garscha U.
    Biochim Biophys Acta; 2014 Sep 01; 1840(9):2961-9. PubMed ID: 24905297
    [Abstract] [Full Text] [Related]

  • 5. Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes.
    Werz O, Bürkert E, Samuelsson B, Rådmark O, Steinhilber D.
    Blood; 2002 Feb 01; 99(3):1044-52. PubMed ID: 11807011
    [Abstract] [Full Text] [Related]

  • 6. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
    Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.
    Inflamm Res; 1997 May 01; 46(5):168-79. PubMed ID: 9197987
    [Abstract] [Full Text] [Related]

  • 7. Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610.
    Fischer L, Steinhilber D, Werz O.
    Br J Pharmacol; 2004 Jul 01; 142(5):861-8. PubMed ID: 15197110
    [Abstract] [Full Text] [Related]

  • 8. Licofelone, a dual lipoxygenase-cyclooxygenase inhibitor, downregulates polymorphonuclear leukocyte and platelet function.
    Rotondo S, Dell'Elba G, Krauze-Brzósko K, Manarini S, Martelli N, Pecce R, Evangelista V, Cerletti C.
    Eur J Pharmacol; 2002 Oct 18; 453(1):131-9. PubMed ID: 12393068
    [Abstract] [Full Text] [Related]

  • 9. Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase.
    Hutchinson JH, Charleson S, Evans JF, Falgueyret JP, Hoogsteen K, Jones TR, Kargman S, Macdonald D, McFarlane CS, Nicholson DW.
    J Med Chem; 1995 Oct 27; 38(22):4538-47. PubMed ID: 7473582
    [Abstract] [Full Text] [Related]

  • 10. Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin.
    Schaible AM, Traber H, Temml V, Noha SM, Filosa R, Peduto A, Weinigel C, Barz D, Schuster D, Werz O.
    Biochem Pharmacol; 2013 Aug 15; 86(4):476-86. PubMed ID: 23623753
    [Abstract] [Full Text] [Related]

  • 11. p38 MAP kinase mediates stress-induced leukotriene synthesis in a human B-lymphocyte cell line.
    Werz O, Klemm J, Rådmark O, Samuelsson B.
    J Leukoc Biol; 2001 Nov 15; 70(5):830-8. PubMed ID: 11698504
    [Abstract] [Full Text] [Related]

  • 12. 5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes.
    Woods JW, Evans JF, Ethier D, Scott S, Vickers PJ, Hearn L, Heibein JA, Charleson S, Singer II.
    J Exp Med; 1993 Dec 01; 178(6):1935-46. PubMed ID: 8245774
    [Abstract] [Full Text] [Related]

  • 13. Reversal of human neutrophil survival by leukotriene B(4) receptor blockade and 5-lipoxygenase and 5-lipoxygenase activating protein inhibitors.
    Lee E, Lindo T, Jackson N, Meng-Choong L, Reynolds P, Hill A, Haswell M, Jackson S, Kilfeather S.
    Am J Respir Crit Care Med; 1999 Dec 01; 160(6):2079-85. PubMed ID: 10588632
    [Abstract] [Full Text] [Related]

  • 14. Prostaglandins inhibit 5-lipoxygenase-activating protein expression and leukotriene B4 production from dendritic cells via an IL-10-dependent mechanism.
    Harizi H, Juzan M, Moreau JF, Gualde N.
    J Immunol; 2003 Jan 01; 170(1):139-46. PubMed ID: 12496393
    [Abstract] [Full Text] [Related]

  • 15. A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells.
    Kargman S, Vickers PJ, Evans JF.
    J Cell Biol; 1992 Dec 01; 119(6):1701-9. PubMed ID: 1469057
    [Abstract] [Full Text] [Related]

  • 16. A new class of leukotriene biosynthesis inhibitor: the development of MK-0591.
    Prasit P, Belley M, Blouin M, Brideau C, Chan C, Charleson S, Evans JF, Frenette R, Gauthier JY, Guay J.
    J Lipid Mediat; 1993 Dec 01; 6(1-3):239-44. PubMed ID: 8357985
    [Abstract] [Full Text] [Related]

  • 17. 5-lipoxygenase and FLAP.
    Peters-Golden M, Brock TG.
    Prostaglandins Leukot Essent Fatty Acids; 2003 Dec 01; 69(2-3):99-109. PubMed ID: 12895592
    [Abstract] [Full Text] [Related]

  • 18. Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood monocytes into alveolar macrophages.
    Coffey MJ, Wilcoxen SE, Peters-Golden M.
    Am J Respir Cell Mol Biol; 1994 Aug 01; 11(2):153-8. PubMed ID: 8049076
    [Abstract] [Full Text] [Related]

  • 19. P2X7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl leukotrienes.
    Ballerini P, Ciccarelli R, Caciagli F, Rathbone MP, Werstiuk ES, Traversa U, Buccella S, Giuliani P, Jang S, Nargi E, Visini D, Santavenere C, Di Iorio P.
    Int J Immunopathol Pharmacol; 2005 Aug 01; 18(3):417-30. PubMed ID: 16164825
    [Abstract] [Full Text] [Related]

  • 20. Activation of leukotriene synthesis in human neutrophils by exogenous arachidonic acid: inhibition by adenosine A(2a) receptor agonists and crucial role of autocrine activation by leukotriene B(4).
    Surette ME, Krump E, Picard S, Borgeat P.
    Mol Pharmacol; 1999 Nov 01; 56(5):1055-62. PubMed ID: 10531413
    [Abstract] [Full Text] [Related]


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