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493 related items for PubMed ID: 17709141

  • 1. Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor.
    Kerr FK, Thomas AR, Wijeyewickrema LC, Whisstock JC, Boyd SE, Kaiserman D, Matthews AY, Bird PI, Thielens NM, Rossi V, Pike RN.
    Mol Immunol; 2008 Feb; 45(3):670-7. PubMed ID: 17709141
    [Abstract] [Full Text] [Related]

  • 2. Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement.
    Nielsen EW, Waage C, Fure H, Brekke OL, Sfyroera G, Lambris JD, Mollnes TE.
    Mol Immunol; 2007 Mar; 44(8):1819-26. PubMed ID: 17101176
    [Abstract] [Full Text] [Related]

  • 3. Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation.
    Kocsis A, Kékesi KA, Szász R, Végh BM, Balczer J, Dobó J, Závodszky P, Gál P, Pál G.
    J Immunol; 2010 Oct 01; 185(7):4169-78. PubMed ID: 20817870
    [Abstract] [Full Text] [Related]

  • 4. MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity.
    Dobó J, Harmat V, Beinrohr L, Sebestyén E, Závodszky P, Gál P.
    J Immunol; 2009 Jul 15; 183(2):1207-14. PubMed ID: 19564340
    [Abstract] [Full Text] [Related]

  • 5. The control of the complement lectin pathway activation revisited: both C1-inhibitor and antithrombin are likely physiological inhibitors, while α2-macroglobulin is not.
    Paréj K, Dobó J, Závodszky P, Gál P.
    Mol Immunol; 2013 Jul 15; 54(3-4):415-22. PubMed ID: 23399388
    [Abstract] [Full Text] [Related]

  • 6. A novel measurement method for activation of the lectin complement pathway via both mannose-binding lectin (MBL) and L-ficolin.
    Inoshita H, Matsushita M, Koide S, Kusaba G, Ishii M, Onda K, Gi MJ, Nakata M, Ohsawa I, Horikoshi S, Ohi H, Tomino Y.
    J Immunol Methods; 2009 Sep 30; 349(1-2):9-17. PubMed ID: 19699205
    [Abstract] [Full Text] [Related]

  • 7. Importance of the prime subsites of the C1s protease of the classical complement pathway for recognition of substrates.
    O'Brien G, Quinsey NS, Whisstock JC, Pike RN.
    Biochemistry; 2003 Dec 23; 42(50):14939-45. PubMed ID: 14674770
    [Abstract] [Full Text] [Related]

  • 8. The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions.
    Harmat V, Gál P, Kardos J, Szilágyi K, Ambrus G, Végh B, Náray-Szabó G, Závodszky P.
    J Mol Biol; 2004 Oct 01; 342(5):1533-46. PubMed ID: 15364579
    [Abstract] [Full Text] [Related]

  • 9. Activation of the alternative complement pathway by mannose-binding lectin via a C2-bypass pathway.
    Tateishi K, Matsushita M.
    Microbiol Immunol; 2011 Nov 01; 55(11):817-21. PubMed ID: 21831201
    [Abstract] [Full Text] [Related]

  • 10. Assembly of C1 and the MBL- and ficolin-MASP complexes: structural insights.
    Gaboriaud C, Teillet F, Gregory LA, Thielens NM, Arlaud GJ.
    Immunobiology; 2007 Nov 01; 212(4-5):279-88. PubMed ID: 17544813
    [Abstract] [Full Text] [Related]

  • 11. Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi.
    Cestari Idos S, Krarup A, Sim RB, Inal JM, Ramirez MI.
    Mol Immunol; 2009 Dec 01; 47(2-3):426-37. PubMed ID: 19783051
    [Abstract] [Full Text] [Related]

  • 12. TFPI inhibits lectin pathway of complement activation by direct interaction with MASP-2.
    Keizer MP, Pouw RB, Kamp AM, Patiwael S, Marsman G, Hart MH, Zeerleder S, Kuijpers TW, Wouters D.
    Eur J Immunol; 2015 Feb 01; 45(2):544-50. PubMed ID: 25359215
    [Abstract] [Full Text] [Related]

  • 13. A second serine protease associated with mannan-binding lectin that activates complement.
    Thiel S, Vorup-Jensen T, Stover CM, Schwaeble W, Laursen SB, Poulsen K, Willis AC, Eggleton P, Hansen S, Holmskov U, Reid KB, Jensenius JC.
    Nature; 1997 Apr 03; 386(6624):506-10. PubMed ID: 9087411
    [Abstract] [Full Text] [Related]

  • 14. C1, MBL-MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation.
    Beinrohr L, Dobó J, Závodszky P, Gál P.
    Trends Mol Med; 2008 Dec 03; 14(12):511-21. PubMed ID: 18977695
    [Abstract] [Full Text] [Related]

  • 15. MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway.
    Vorup-Jensen T, Jensenius JC, Thiel S.
    Immunobiology; 1998 Aug 03; 199(2):348-57. PubMed ID: 9777418
    [Abstract] [Full Text] [Related]

  • 16. Structural and functional overview of the lectin complement pathway: its molecular basis and physiological implication.
    Matsushita M, Endo Y, Fujita T.
    Arch Immunol Ther Exp (Warsz); 2013 Aug 03; 61(4):273-83. PubMed ID: 23563865
    [Abstract] [Full Text] [Related]

  • 17. Toward a structure-based comprehension of the lectin pathway of complement.
    Kjaer TR, Thiel S, Andersen GR.
    Mol Immunol; 2013 Dec 03; 56(4):413-22. PubMed ID: 23911397
    [Abstract] [Full Text] [Related]

  • 18. Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway.
    Møller-Kristensen M, Thiel S, Sjöholm A, Matsushita M, Jensenius JC.
    Int Immunol; 2007 Feb 03; 19(2):141-9. PubMed ID: 17182967
    [Abstract] [Full Text] [Related]

  • 19. MBL-associated serine protease-3 circulates in high serum concentrations predominantly in complex with Ficolin-3 and regulates Ficolin-3 mediated complement activation.
    Skjoedt MO, Palarasah Y, Munthe-Fog L, Jie Ma Y, Weiss G, Skjodt K, Koch C, Garred P.
    Immunobiology; 2010 Nov 03; 215(11):921-31. PubMed ID: 19939495
    [Abstract] [Full Text] [Related]

  • 20. Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44.
    Degn SE, Jensen L, Olszowski T, Jensenius JC, Thiel S.
    J Immunol; 2013 Aug 01; 191(3):1334-45. PubMed ID: 23785123
    [Abstract] [Full Text] [Related]

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