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Journal Abstract Search

325 related items for PubMed ID: 17717282

  • 1. Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.
    Oprescu AI, Bikopoulos G, Naassan A, Allister EM, Tang C, Park E, Uchino H, Lewis GF, Fantus IG, Rozakis-Adcock M, Wheeler MB, Giacca A.
    Diabetes; 2007 Dec; 56(12):2927-37. PubMed ID: 17717282
    [Abstract] [Full Text] [Related]

  • 2. Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats.
    Mason TM, Goh T, Tchipashvili V, Sandhu H, Gupta N, Lewis GF, Giacca A.
    Diabetes; 1999 Mar; 48(3):524-30. PubMed ID: 10078552
    [Abstract] [Full Text] [Related]

  • 3. IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.
    Ivovic A, Oprescu AI, Koulajian K, Mori Y, Eversley JA, Zhang L, Nino-Fong R, Lewis GF, Donath MY, Karin M, Wheeler MB, Ehses J, Volchuk A, Chan CB, Giacca A.
    Diabetologia; 2017 Oct; 60(10):2021-2032. PubMed ID: 28725915
    [Abstract] [Full Text] [Related]

  • 4. Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo.
    Tang C, Han P, Oprescu AI, Lee SC, Gyulkhandanyan AV, Chan GN, Wheeler MB, Giacca A.
    Diabetes; 2007 Nov; 56(11):2722-31. PubMed ID: 17682092
    [Abstract] [Full Text] [Related]

  • 5. N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress.
    Haber CA, Lam TK, Yu Z, Gupta N, Goh T, Bogdanovic E, Giacca A, Fantus IG.
    Am J Physiol Endocrinol Metab; 2003 Oct; 285(4):E744-53. PubMed ID: 12799318
    [Abstract] [Full Text] [Related]

  • 6. Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.
    Piro S, Anello M, Di Pietro C, Lizzio MN, Patanè G, Rabuazzo AM, Vigneri R, Purrello M, Purrello F.
    Metabolism; 2002 Oct; 51(10):1340-7. PubMed ID: 12370856
    [Abstract] [Full Text] [Related]

  • 7. Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.
    Bollheimer LC, Skelly RH, Chester MW, McGarry JD, Rhodes CJ.
    J Clin Invest; 1998 Mar 01; 101(5):1094-101. PubMed ID: 9486980
    [Abstract] [Full Text] [Related]

  • 8. Effects of different free fatty acids on insulin resistance in rats.
    Han P, Zhang YY, Lu Y, He B, Zhang W, Xia F.
    Hepatobiliary Pancreat Dis Int; 2008 Feb 01; 7(1):91-6. PubMed ID: 18234646
    [Abstract] [Full Text] [Related]

  • 9. Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.
    Lupi R, Del Guerra S, Marselli L, Bugliani M, Boggi U, Mosca F, Marchetti P, Del Prato S.
    Am J Physiol Endocrinol Metab; 2004 Apr 01; 286(4):E560-7. PubMed ID: 14625208
    [Abstract] [Full Text] [Related]

  • 10. Taurine prevents free fatty acid-induced hepatic insulin resistance in association with inhibiting JNK1 activation and improving insulin signaling in vivo.
    Wu N, Lu Y, He B, Zhang Y, Lin J, Zhao S, Zhang W, Li Y, Han P.
    Diabetes Res Clin Pract; 2010 Dec 01; 90(3):288-96. PubMed ID: 20855122
    [Abstract] [Full Text] [Related]

  • 11. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
    Zhou YP, Grill VE.
    J Clin Invest; 1994 Feb 01; 93(2):870-6. PubMed ID: 8113418
    [Abstract] [Full Text] [Related]

  • 12. Acute and chronic effects of different concentrations of free fatty acids on the insulin secreting function of islets.
    Ayvaz G, Balos Törüner F, Karakoç A, Yetkin I, Cakir N, Arslan M.
    Diabetes Metab; 2002 Dec 01; 28(6 Pt 2):3S7-12; discussion 3S108-12. PubMed ID: 12688627
    [Abstract] [Full Text] [Related]

  • 13. Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivo.
    Koulajian K, Ivovic A, Ye K, Desai T, Shah A, Fantus IG, Ran Q, Giacca A.
    Am J Physiol Endocrinol Metab; 2013 Jul 15; 305(2):E254-62. PubMed ID: 23695217
    [Abstract] [Full Text] [Related]

  • 14. Effect of N-acetyl-l-cysteine on insulin resistance caused by prolonged free fatty acid elevation.
    Pereira S, Shah A, George Fantus I, Joseph JW, Giacca A.
    J Endocrinol; 2015 Apr 15; 225(1):1-7. PubMed ID: 25609734
    [Abstract] [Full Text] [Related]

  • 15. β-Cell Insulin Resistance Plays a Causal Role in Fat-Induced β-Cell Dysfunction In Vitro and In Vivo.
    Ivovic A, Yung JHM, Oprescu AI, Vlavcheski F, Mori Y, Rahman SMN, Ye W, Eversley JA, Wheeler MB, Woo M, Tsiani E, Giacca A.
    Endocrinology; 2024 Mar 29; 165(5):. PubMed ID: 38578954
    [Abstract] [Full Text] [Related]

  • 16. NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.
    Koulajian K, Desai T, Liu GC, Ivovic A, Patterson JN, Tang C, El-Benna J, Joseph JW, Scholey JW, Giacca A.
    Diabetologia; 2013 May 29; 56(5):1078-87. PubMed ID: 23429921
    [Abstract] [Full Text] [Related]

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  • 18. Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans.
    Dobbins RL, Chester MW, Daniels MB, McGarry JD, Stein DT.
    Diabetes; 1998 Oct 29; 47(10):1613-8. PubMed ID: 9753300
    [Abstract] [Full Text] [Related]

  • 19. Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells.
    Patanè G, Piro S, Rabuazzo AM, Anello M, Vigneri R, Purrello F.
    Diabetes; 2000 May 29; 49(5):735-40. PubMed ID: 10905481
    [Abstract] [Full Text] [Related]

  • 20. Elevated circulating free fatty acids levels causing pancreatic islet cell dysfunction through oxidative stress.
    Zhang X, Bao Y, Ke L, Yu Y.
    J Endocrinol Invest; 2010 Jun 29; 33(6):388-94. PubMed ID: 19915385
    [Abstract] [Full Text] [Related]

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