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Journal Abstract Search

216 related items for PubMed ID: 17718999

  • 1. Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitors.
    Choi KJ, Noh KM, Kim DE, Ha BH, Kim EE, Yoon MY.
    Arch Biochem Biophys; 2007 Oct 01; 466(1):24-30. PubMed ID: 17718999
    [Abstract] [Full Text] [Related]

  • 2. Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library.
    Choi KJ, Yu YG, Hahn HG, Choi JD, Yoon MY.
    FEBS Lett; 2005 Aug 29; 579(21):4903-10. PubMed ID: 16111681
    [Abstract] [Full Text] [Related]

  • 3. Cloning, characterization and evaluation of potent inhibitors of Shigella sonnei acetohydroxyacid synthase catalytic subunit.
    Lim WM, Baig IJ, La IJ, Choi JD, Kim DE, Kim SK, Hyun JW, Kim G, Kang CH, Kim YJ, Yoon MY.
    Biochim Biophys Acta; 2011 Dec 29; 1814(12):1825-31. PubMed ID: 22015678
    [Abstract] [Full Text] [Related]

  • 4. Identification and characterization of inhibitors of Haemophilus influenzae acetohydroxyacid synthase.
    Gedi V, Moon JY, Lim WM, Lee MY, Lee SC, Koo BS, Govindwar S, Yoon MY.
    Enzyme Microb Technol; 2011 Jun 10; 49(1):1-5. PubMed ID: 22112263
    [Abstract] [Full Text] [Related]

  • 5. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase.
    Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY.
    Biochimie; 2013 Jul 10; 95(7):1411-21. PubMed ID: 23523771
    [Abstract] [Full Text] [Related]

  • 6. Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.
    Pham NC, Moon JY, Cho JH, Lee SJ, Park JS, Kim DE, Park Y, Yoon MY.
    Biosci Biotechnol Biochem; 2010 Jul 10; 74(11):2281-6. PubMed ID: 21071847
    [Abstract] [Full Text] [Related]

  • 7. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I.
    Belenky I, Steinmetz A, Vyazmensky M, Barak Z, Tittmann K, Chipman DM.
    FEBS J; 2012 Jun 10; 279(11):1967-79. PubMed ID: 22443469
    [Abstract] [Full Text] [Related]

  • 8. Mutations in the regulatory subunit of yeast acetohydroxyacid synthase affect its activation by MgATP.
    Lee YT, Duggleby RG.
    Biochem J; 2006 Apr 15; 395(2):331-6. PubMed ID: 16390333
    [Abstract] [Full Text] [Related]

  • 9. Valine 375 and phenylalanine 109 confer affinity and specificity for pyruvate as donor substrate in acetohydroxy acid synthase isozyme II from Escherichia coli.
    Steinmetz A, Vyazmensky M, Meyer D, Barak ZE, Golbik R, Chipman DM, Tittmann K.
    Biochemistry; 2010 Jun 29; 49(25):5188-99. PubMed ID: 20504042
    [Abstract] [Full Text] [Related]

  • 10. Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzyme.
    Tittmann K, Schröder K, Golbik R, McCourt J, Kaplun A, Duggleby RG, Barak Z, Chipman DM, Hübner G.
    Biochemistry; 2004 Jul 13; 43(27):8652-61. PubMed ID: 15236573
    [Abstract] [Full Text] [Related]

  • 11. Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors.
    Pang SS, Duggleby RG, Guddat LW.
    J Mol Biol; 2002 Mar 22; 317(2):249-62. PubMed ID: 11902841
    [Abstract] [Full Text] [Related]

  • 12. Bacterial acetohydroxyacid synthase and its inhibitors--a summary of their structure, biological activity and current status.
    Gedi V, Yoon MY.
    FEBS J; 2012 Mar 22; 279(6):946-63. PubMed ID: 22284339
    [Abstract] [Full Text] [Related]

  • 13. Interactions between large and small subunits of different acetohydroxyacid synthase isozymes of Escherichia coli.
    Vyazmensky M, Zherdev Y, Slutzker A, Belenky I, Kryukov O, Barak Z, Chipman DM.
    Biochemistry; 2009 Sep 15; 48(36):8731-7. PubMed ID: 19653643
    [Abstract] [Full Text] [Related]

  • 14. Significant catalytic roles for Glu47 and Gln 110 in all four of the C-C bond-making and -breaking steps of the reactions of acetohydroxyacid synthase II.
    Vyazmensky M, Steinmetz A, Meyer D, Golbik R, Barak Z, Tittmann K, Chipman DM.
    Biochemistry; 2011 Apr 19; 50(15):3250-60. PubMed ID: 21370850
    [Abstract] [Full Text] [Related]

  • 15. Role of a highly conserved proline-126 in ThDP binding of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA, Gedi V, Lee SC, Koh SH, Yoon MY.
    Enzyme Microb Technol; 2013 Sep 10; 53(4):243-9. PubMed ID: 23931689
    [Abstract] [Full Text] [Related]

  • 16. Computational determination of fundamental pathway and activation barriers for acetohydroxyacid synthase-catalyzed condensation reactions of alpha-keto acids.
    Xiong Y, Liu J, Yang GF, Zhan CG.
    J Comput Chem; 2010 Jun 10; 31(8):1592-602. PubMed ID: 19554557
    [Abstract] [Full Text] [Related]

  • 17. Acetohydroxyacid synthase: a proposed structure for regulatory subunits supported by evidence from mutagenesis.
    Mendel S, Elkayam T, Sella C, Vinogradov V, Vyazmensky M, Chipman DM, Barak Z.
    J Mol Biol; 2001 Mar 16; 307(1):465-77. PubMed ID: 11243831
    [Abstract] [Full Text] [Related]

  • 18. Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.
    Wang JG, Lee PK, Dong YH, Pang SS, Duggleby RG, Li ZM, Guddat LW.
    FEBS J; 2009 Mar 16; 276(5):1282-90. PubMed ID: 19187232
    [Abstract] [Full Text] [Related]

  • 19. Structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from Escherichia coli.
    Kaplun A, Vyazmensky M, Zherdev Y, Belenky I, Slutzker A, Mendel S, Barak Z, Chipman DM, Shaanan B.
    J Mol Biol; 2006 Mar 31; 357(3):951-63. PubMed ID: 16458324
    [Abstract] [Full Text] [Related]

  • 20. The carboligation reaction of acetohydroxyacid synthase II: steady-state intermediate distributions in wild type and mutants by NMR.
    Tittmann K, Vyazmensky M, Hübner G, Barak Z, Chipman DM.
    Proc Natl Acad Sci U S A; 2005 Jan 18; 102(3):553-8. PubMed ID: 15640355
    [Abstract] [Full Text] [Related]

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