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Journal Abstract Search

330 related items for PubMed ID: 17726343

  • 1. Inhibition of phosphodiesterase type 4 decreases stress-induced defecation in rats and mice.
    Barone FC, Barton ME, White RF, Legos JJ, Kikkawa H, Shimamura M, Kuratani K, Kinoshita M.
    Pharmacology; 2008; 81(1):11-7. PubMed ID: 17726343
    [Abstract] [Full Text] [Related]

  • 2. The identification of a novel phosphodiesterase 4 inhibitor, 1-ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with improved therapeutic index using pica feeding in rats as a measure of emetogenicity.
    Davis TG, Peterson JJ, Kou JP, Capper-Spudich EA, Ball D, Nials AT, Wiseman J, Solanke YE, Lucas FS, Williamson RA, Ferrari L, Wren P, Knowles RG, Barnette MS, Podolin PL.
    J Pharmacol Exp Ther; 2009 Sep; 330(3):922-31. PubMed ID: 19498103
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors.
    Wollin L, Bundschuh DS, Wohlsen A, Marx D, Beume R.
    Pulm Pharmacol Ther; 2006 Sep; 19(5):343-52. PubMed ID: 16257550
    [Abstract] [Full Text] [Related]

  • 4. Effect of inhaled roflumilast on the prevention and resolution of allergen-induced late phase airflow obstruction in Brown Norway rats.
    Chapman RW, House A, Jones H, Richard J, Celly C, Prelusky D, Ting P, Hunter JC, Lamca J, Phillips JE.
    Eur J Pharmacol; 2007 Oct 01; 571(2-3):215-21. PubMed ID: 17610865
    [Abstract] [Full Text] [Related]

  • 5. In vivo efficacy in airway disease models of roflumilast, a novel orally active PDE4 inhibitor.
    Bundschuh DS, Eltze M, Barsig J, Wollin L, Hatzelmann A, Beume R.
    J Pharmacol Exp Ther; 2001 Apr 01; 297(1):280-90. PubMed ID: 11259555
    [Abstract] [Full Text] [Related]

  • 6. Effect of ramosetron on conditioned emotional stress-induced colonic dysfunction as a model of irritable bowel syndrome in rats.
    Funatsu T, Takeuchi A, Hirata T, Keto Y, Akuzawa S, Sasamata M.
    Eur J Pharmacol; 2007 Nov 14; 573(1-3):190-5. PubMed ID: 17658508
    [Abstract] [Full Text] [Related]

  • 7. Curative effects of phosphodiesterase 4 inhibitors cilomilast, roflumilast, and rolipram in dermatitis mouse model.
    Harada D, Ikeda Y, Nosaka Y, Kobayashi K, Manabe H.
    J Dermatol Sci; 2008 Sep 14; 51(3):215-9. PubMed ID: 18539440
    [No Abstract] [Full Text] [Related]

  • 8. Action of a Novel PDE4 inhibitor ZL-n-91 on lipopolysaccharide-induced acute lung injury.
    Tang HF, Lu JJ, Tang JF, Zheng X, Liang YQ, Wang XF, Wang YJ, Mao LG, Chen JQ.
    Int Immunopharmacol; 2010 Apr 14; 10(4):406-11. PubMed ID: 20074667
    [Abstract] [Full Text] [Related]

  • 9. Phosphodiesterase inhibitors in airways disease.
    Fan Chung K.
    Eur J Pharmacol; 2006 Mar 08; 533(1-3):110-7. PubMed ID: 16458289
    [Abstract] [Full Text] [Related]

  • 10. Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells.
    Growcott EJ, Spink KG, Ren X, Afzal S, Banner KH, Wharton J.
    Respir Res; 2006 Jan 19; 7(1):9. PubMed ID: 16423283
    [Abstract] [Full Text] [Related]

  • 11. Effect of orally administered rolipram, a phosphodiesterase 4 inhibitor, on a mouse model of the dermatitis caused by 2,4,6-trinitro-1-chlorobenzene (TNCB)-repeated application.
    Harada D, Tsukumo Y, Takashima Y, Manabe H.
    Eur J Pharmacol; 2006 Feb 17; 532(1-2):128-37. PubMed ID: 16442096
    [Abstract] [Full Text] [Related]

  • 12. Pharmacology of a novel, orally active PDE4 inhibitor.
    Dastidar SG, Ray A, Shirumalla R, Rajagopal D, Chaudhary S, Nanda K, Sharma P, Seth MK, Balachandran S, Gupta N, Palle V.
    Pharmacology; 2009 Feb 17; 83(5):275-86. PubMed ID: 19321962
    [Abstract] [Full Text] [Related]

  • 13. Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke.
    Martorana PA, Beume R, Lucattelli M, Wollin L, Lungarella G.
    Am J Respir Crit Care Med; 2005 Oct 01; 172(7):848-53. PubMed ID: 15961691
    [Abstract] [Full Text] [Related]

  • 14. Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats.
    Makhay MM, Houslay MD, O'Donnell JM.
    Psychopharmacology (Berl); 2001 Nov 01; 158(3):297-304. PubMed ID: 11713620
    [Abstract] [Full Text] [Related]

  • 15. Rolipram, a specific type-4 phosphodiesterase inhibitor, inhibits cyclophosphamide-induced haemorrhagic cystitis in rats.
    Sakura M, Masuda H, Matsuoka Y, Yokoyama M, Kawakami S, Kihara K.
    BJU Int; 2009 Jan 01; 103(2):264-9. PubMed ID: 18710439
    [Abstract] [Full Text] [Related]

  • 16. The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses.
    Vanmierlo T, Creemers P, Akkerman S, van Duinen M, Sambeth A, De Vry J, Uz T, Blokland A, Prickaerts J.
    Behav Brain Res; 2016 Apr 15; 303():26-33. PubMed ID: 26794595
    [Abstract] [Full Text] [Related]

  • 17. Selective inhibition of phosphodiesterase-4 ameliorates chronic colitis and prevents intestinal fibrosis.
    Videla S, Vilaseca J, Medina C, Mourelle M, Guarner F, Salas A, Malagelada JR.
    J Pharmacol Exp Ther; 2006 Feb 15; 316(2):940-5. PubMed ID: 16254133
    [Abstract] [Full Text] [Related]

  • 18. Effect of change in an inhibitory neurotransmitter of the myenteric plexus on the pathogenetic mechanism of irritable bowel syndrome subgroups in rat models.
    Xu JR, Luo JY, Shang L, Kong WM.
    Chin J Dig Dis; 2006 Feb 15; 7(2):89-96. PubMed ID: 16643336
    [Abstract] [Full Text] [Related]

  • 19. Cold-restraint stress increases rat fecal pellet output and colonic transit.
    Barone FC, Deegan JF, Price WJ, Fowler PJ, Fondacaro JD, Ormsbee HS.
    Am J Physiol; 1990 Mar 15; 258(3 Pt 1):G329-37. PubMed ID: 2316647
    [Abstract] [Full Text] [Related]

  • 20. Phosphodiesterase type 4 inhibitor prevents acute lung injury induced by cardiopulmonary bypass in a rat model.
    Hamamoto M, Suga M, Nakatani T, Takahashi Y, Sato Y, Inamori S, Yagihara T, Kitamura S.
    Eur J Cardiothorac Surg; 2004 May 15; 25(5):833-8. PubMed ID: 15082290
    [Abstract] [Full Text] [Related]

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