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Journal Abstract Search

185 related items for PubMed ID: 17760810

  • 1. Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells.
    Hideshima T, Catley L, Raje N, Chauhan D, Podar K, Mitsiades C, Tai YT, Vallet S, Kiziltepe T, Ocio E, Ikeda H, Okawa Y, Hideshima H, Munshi NC, Yasui H, Richardson PG, Anderson KC.
    Br J Haematol; 2007 Sep; 138(6):783-91. PubMed ID: 17760810
    [Abstract] [Full Text] [Related]

  • 2. Perifosine synergistically enhances TRAIL-induced myeloma cell apoptosis via up-regulation of death receptors.
    David E, Sinha R, Chen J, Sun SY, Kaufman JL, Lonial S.
    Clin Cancer Res; 2008 Aug 15; 14(16):5090-8. PubMed ID: 18698026
    [Abstract] [Full Text] [Related]

  • 3. MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo.
    Hideshima T, Neri P, Tassone P, Yasui H, Ishitsuka K, Raje N, Chauhan D, Podar K, Mitsiades C, Dang L, Munshi N, Richardson P, Schenkein D, Anderson KC.
    Clin Cancer Res; 2006 Oct 01; 12(19):5887-94. PubMed ID: 17020997
    [Abstract] [Full Text] [Related]

  • 4. The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
    Kumar A, Fillmore HL, Kadian R, Broaddus WC, Tye GW, Van Meter TE.
    Mol Cancer Res; 2009 Nov 01; 7(11):1813-21. PubMed ID: 19887560
    [Abstract] [Full Text] [Related]

  • 5. Celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt.
    Liu B, Shi ZL, Feng J, Tao HM.
    Cell Biol Int; 2008 May 01; 32(5):494-501. PubMed ID: 18078766
    [Abstract] [Full Text] [Related]

  • 6. Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells.
    Wang J, Yang L, Yang J, Kuropatwinski K, Wang W, Liu XQ, Hauser J, Brattain MG.
    Cancer Res; 2008 May 01; 68(9):3152-60. PubMed ID: 18451140
    [Abstract] [Full Text] [Related]

  • 7. Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis.
    Tang C, Lu YH, Xie JH, Wang F, Zou JN, Yang JS, Xing YY, Xi T.
    Anticancer Drugs; 2009 Apr 01; 20(4):249-58. PubMed ID: 19174695
    [Abstract] [Full Text] [Related]

  • 8. A pivotal role for Mcl-1 in Bortezomib-induced apoptosis.
    Podar K, Gouill SL, Zhang J, Opferman JT, Zorn E, Tai YT, Hideshima T, Amiot M, Chauhan D, Harousseau JL, Anderson KC.
    Oncogene; 2008 Jan 31; 27(6):721-31. PubMed ID: 17653083
    [Abstract] [Full Text] [Related]

  • 9. The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
    Chiarini F, Del Sole M, Mongiorgi S, Gaboardi GC, Cappellini A, Mantovani I, Follo MY, McCubrey JA, Martelli AM.
    Leukemia; 2008 Jun 31; 22(6):1106-16. PubMed ID: 18385752
    [Abstract] [Full Text] [Related]

  • 10. Epigallocatechin-3 gallate induces growth inhibition and apoptosis in human breast cancer cells through survivin suppression.
    Tang Y, Zhao DY, Elliott S, Zhao W, Curiel TJ, Beckman BS, Burow ME.
    Int J Oncol; 2007 Oct 31; 31(4):705-11. PubMed ID: 17786300
    [Abstract] [Full Text] [Related]

  • 11. FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance.
    Yasui H, Hideshima T, Raje N, Roccaro AM, Shiraishi N, Kumar S, Hamasaki M, Ishitsuka K, Tai YT, Podar K, Catley L, Mitsiades CS, Richardson PG, Albert R, Brinkmann V, Chauhan D, Anderson KC.
    Cancer Res; 2005 Aug 15; 65(16):7478-84. PubMed ID: 16103102
    [Abstract] [Full Text] [Related]

  • 12. Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.
    Engel JB, Honig A, Schönhals T, Weidler C, Häusler S, Krockenberger M, Grunewald TG, Dombrowski Y, Rieger L, Dietl J, Wischhusen J.
    Eur J Obstet Gynecol Reprod Biol; 2008 Nov 15; 141(1):64-9. PubMed ID: 18687514
    [Abstract] [Full Text] [Related]

  • 13. The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro.
    Poulaki V, Mitsiades CS, Kotoula V, Negri J, McMillin D, Miller JW, Mitsiades N.
    Invest Ophthalmol Vis Sci; 2007 Oct 15; 48(10):4706-19. PubMed ID: 17898295
    [Abstract] [Full Text] [Related]

  • 14. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
    Cirstea D, Hideshima T, Rodig S, Santo L, Pozzi S, Vallet S, Ikeda H, Perrone G, Gorgun G, Patel K, Desai N, Sportelli P, Kapoor S, Vali S, Mukherjee S, Munshi NC, Anderson KC, Raje N.
    Mol Cancer Ther; 2010 Apr 15; 9(4):963-75. PubMed ID: 20371718
    [Abstract] [Full Text] [Related]

  • 15. Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells.
    Kami K, Doi R, Koizumi M, Toyoda E, Mori T, Ito D, Kawaguchi Y, Fujimoto K, Wada M, Miyatake S, Imamura M.
    Surgery; 2005 Aug 15; 138(2):299-305. PubMed ID: 16153440
    [Abstract] [Full Text] [Related]

  • 16. In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells.
    Neri P, Yasui H, Hideshima T, Tassone P, Raje N, Catley LP, Ishitsuka K, Blotta S, Kiziltepe T, Ocio EM, Fulciniti M, Kanekal S, Elliott GT, Munshi NC, Anderson KC.
    Br J Haematol; 2006 Jul 15; 134(1):37-44. PubMed ID: 16803565
    [Abstract] [Full Text] [Related]

  • 17. Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis.
    Tai YT, Fulciniti M, Hideshima T, Song W, Leiba M, Li XF, Rumizen M, Burger P, Morrison A, Podar K, Chauhan D, Tassone P, Richardson P, Munshi NC, Ghobrial IM, Anderson KC.
    Blood; 2007 Sep 01; 110(5):1656-63. PubMed ID: 17510321
    [Abstract] [Full Text] [Related]

  • 18. Moving disease biology from the lab to the clinic.
    Anderson KC.
    Cancer; 2003 Feb 01; 97(3 Suppl):796-801. PubMed ID: 12548578
    [Abstract] [Full Text] [Related]

  • 19. Triptolide overcomes dexamethasone resistance and enhanced PS-341-induced apoptosis via PI3k/Akt/NF-kappaB pathways in human multiple myeloma cells.
    Yang M, Huang J, Pan HZ, Jin J.
    Int J Mol Med; 2008 Oct 01; 22(4):489-96. PubMed ID: 18813856
    [Abstract] [Full Text] [Related]

  • 20. Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin.
    Torres VA, Tapia JC, Rodríguez DA, Párraga M, Lisboa P, Montoya M, Leyton L, Quest AF.
    J Cell Sci; 2006 May 01; 119(Pt 9):1812-23. PubMed ID: 16608879
    [Abstract] [Full Text] [Related]

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