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Journal Abstract Search

319 related items for PubMed ID: 17764444

  • 1. The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alpha.
    Liu FJ, Song X, Yang D, Deng R, Yan B.
    Biochem J; 2008 Jan 01; 409(1):243-50. PubMed ID: 17764444
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  • 2. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
    Li T, Chiang JY.
    Drug Metab Dispos; 2006 May 01; 34(5):756-64. PubMed ID: 16455805
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  • 3. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X, Xie M, Zhang H, Li Y, Sachdeva K, Yan B.
    Drug Metab Dispos; 2004 Jan 01; 32(1):35-42. PubMed ID: 14709618
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  • 4. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.
    Lim YP, Kuo SC, Lai ML, Huang JD.
    Pharmacogenet Genomics; 2009 Jan 01; 19(1):11-24. PubMed ID: 19077665
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  • 5. Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.
    Svecova L, Vrzal R, Burysek L, Anzenbacherova E, Cerveny L, Grim J, Trejtnar F, Kunes J, Pour M, Staud F, Anzenbacher P, Dvorak Z, Pavek P.
    Drug Metab Dispos; 2008 Feb 01; 36(2):339-48. PubMed ID: 17998298
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  • 6. Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor.
    Fang HL, Strom SC, Ellis E, Duanmu Z, Fu J, Duniec-Dmuchowski Z, Falany CN, Falany JL, Kocarek TA, Runge-Morris M.
    J Pharmacol Exp Ther; 2007 Nov 01; 323(2):586-98. PubMed ID: 17687072
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  • 7. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY, Chen CJ, Ma WC, Cheng WK, Lin YN, Lee YR, Chen JJ, Lim YP.
    Phytomedicine; 2017 Dec 01; 36():37-49. PubMed ID: 29157826
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  • 8. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module.
    Goodwin B, Hodgson E, Liddle C.
    Mol Pharmacol; 1999 Dec 01; 56(6):1329-39. PubMed ID: 10570062
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  • 13. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR, Sueyoshi T, Smith CM, Negishi M, Lecluyse EL, Wang H.
    J Pharmacol Exp Ther; 2006 Jun 01; 317(3):1200-9. PubMed ID: 16513849
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  • 15. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB.
    Nat Med; 2003 Feb 01; 9(2):220-4. PubMed ID: 12514743
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  • 16. Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding.
    Istrate MA, Nussler AK, Eichelbaum M, Burk O.
    Biochem Biophys Res Commun; 2010 Mar 19; 393(4):688-93. PubMed ID: 20171174
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  • 20. In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors.
    Zhang W, Purchio A, Chen K, Burns SM, Contag CH, Contag PR.
    Biochem Pharmacol; 2003 Jun 01; 65(11):1889-96. PubMed ID: 12781341
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