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Journal Abstract Search

242 related items for PubMed ID: 17804224

  • 1. Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.
    Skinner PJ, Cherrier MC, Webb PJ, Shin YJ, Gharbaoui T, Lindstrom A, Hong V, Tamura SY, Dang HT, Pride CC, Chen R, Richman JG, Connolly DT, Semple G.
    Bioorg Med Chem Lett; 2007 Oct 15; 17(20):5620-3. PubMed ID: 17804224
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  • 4. Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A.
    Shen HC, Taggart AK, Wilsie LC, Waters MG, Hammond ML, Tata JR, Colletti SL.
    Bioorg Med Chem Lett; 2008 Sep 15; 18(18):4948-51. PubMed ID: 18752940
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  • 10. Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: optimization of in vitro activity.
    Peters JU, Kühne H, Dehmlow H, Grether U, Conte A, Hainzl D, Hertel C, Kratochwil NA, Otteneder M, Narquizian R, Panousis CG, Ricklin F, Röver S.
    Bioorg Med Chem Lett; 2010 Sep 15; 20(18):5426-30. PubMed ID: 20724150
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  • 11. Molecular modeling aided design of nicotinic acid receptor GPR109A agonists.
    Deng Q, Frie JL, Marley DM, Beresis RT, Ren N, Cai TQ, Taggart AK, Cheng K, Carballo-Jane E, Wang J, Tong X, Waters MG, Tata JR, Colletti SL.
    Bioorg Med Chem Lett; 2008 Sep 15; 18(18):4963-7. PubMed ID: 18760600
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  • 12. 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b.
    Semple G, Skinner PJ, Cherrier MC, Webb PJ, Sage CR, Tamura SY, Chen R, Richman JG, Connolly DT.
    J Med Chem; 2006 Feb 23; 49(4):1227-30. PubMed ID: 16480258
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  • 14. Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b.
    Jung JK, Johnson BR, Duong T, Decaire M, Uy J, Gharbaoui T, Boatman PD, Sage CR, Chen R, Richman JG, Connolly DT, Semple G.
    J Med Chem; 2007 Apr 05; 50(7):1445-8. PubMed ID: 17358052
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  • 19. Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A).
    Blad CC, van Veldhoven JP, Klopman C, Wolfram DR, Brussee J, Lane JR, Ijzerman AP.
    J Med Chem; 2012 Apr 12; 55(7):3563-7. PubMed ID: 22420767
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  • 20. Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109A.
    Shen HC, Szymonifka MJ, Kharbanda D, Deng Q, Carballo-Jane E, Wu KK, Wu TJ, Cheng K, Ren N, Cai TQ, Taggart AK, Wang J, Tong X, Waters MG, Hammond ML, Tata JR, Colletti SL.
    Bioorg Med Chem Lett; 2007 Dec 15; 17(24):6723-8. PubMed ID: 18029181
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