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Journal Abstract Search

693 related items for PubMed ID: 17804716

  • 1. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
    Konishi J, Kawaguchi KS, Vo H, Haruki N, Gonzalez A, Carbone DP, Dang TP.
    Cancer Res; 2007 Sep 01; 67(17):8051-7. PubMed ID: 17804716
    [Abstract] [Full Text] [Related]

  • 2. Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer.
    Kondratyev M, Kreso A, Hallett RM, Girgis-Gabardo A, Barcelon ME, Ilieva D, Ware C, Majumder PK, Hassell JA.
    Oncogene; 2012 Jan 05; 31(1):93-103. PubMed ID: 21666715
    [Abstract] [Full Text] [Related]

  • 3. Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo.
    Osanyingbemi-Obidi J, Dobromilskaya I, Illei PB, Hann CL, Rudin CM.
    Mol Cancer Res; 2011 Dec 05; 9(12):1746-54. PubMed ID: 21994468
    [Abstract] [Full Text] [Related]

  • 4. The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models.
    Mizuma M, Rasheed ZA, Yabuuchi S, Omura N, Campbell NR, de Wilde RF, De Oliveira E, Zhang Q, Puig O, Matsui W, Hidalgo M, Maitra A, Rajeshkumar NV.
    Mol Cancer Ther; 2012 Sep 05; 11(9):1999-2009. PubMed ID: 22752426
    [Abstract] [Full Text] [Related]

  • 5. Evodiamine suppresses Notch3 signaling in lung tumorigenesis via direct binding to γ-secretases.
    Yang X, Zhang Y, Huang Y, Wang Y, Qi X, Su T, Lu L.
    Phytomedicine; 2020 Mar 05; 68():153176. PubMed ID: 32045841
    [Abstract] [Full Text] [Related]

  • 6. Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer.
    Sakakibara-Konishi J, Ikezawa Y, Oizumi S, Kikuchi J, Kikuchi E, Mizugaki H, Kinoshita I, Dosaka-Akita H, Nishimura M.
    Int J Clin Oncol; 2017 Apr 05; 22(2):257-268. PubMed ID: 27816990
    [Abstract] [Full Text] [Related]

  • 7. Evaluation of role of Notch3 signaling pathway in human lung cancer cells.
    Hassan WA, Yoshida R, Kudoh S, Motooka Y, Ito T.
    J Cancer Res Clin Oncol; 2016 May 05; 142(5):981-93. PubMed ID: 26838758
    [Abstract] [Full Text] [Related]

  • 8. Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy.
    Liu J, Mao Z, Huang J, Xie S, Liu T, Mao Z.
    Biochem Biophys Res Commun; 2014 Feb 21; 444(4):670-5. PubMed ID: 24502949
    [Abstract] [Full Text] [Related]

  • 9. Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
    Efferson CL, Winkelmann CT, Ware C, Sullivan T, Giampaoli S, Tammam J, Patel S, Mesiti G, Reilly JF, Gibson RE, Buser C, Yeatman T, Coppola D, Winter C, Clark EA, Draetta GF, Strack PR, Majumder PK.
    Cancer Res; 2010 Mar 15; 70(6):2476-84. PubMed ID: 20197467
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of gamma-secretase activity impedes uterine serous carcinoma growth in a human xenograft model.
    Groeneweg JW, Hall TR, Zhang L, Kim M, Byron VF, Tambouret R, Sathayanrayanan S, Foster R, Rueda BR, Growdon WB.
    Gynecol Oncol; 2014 Jun 15; 133(3):607-15. PubMed ID: 24667249
    [Abstract] [Full Text] [Related]

  • 11. Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells.
    Timme CR, Gruidl M, Yeatman TJ.
    Apoptosis; 2013 Oct 15; 18(10):1163-74. PubMed ID: 23887890
    [Abstract] [Full Text] [Related]

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  • 13. Notch signaling activation in pediatric low-grade astrocytoma.
    Brandt WD, Schreck KC, Bar EE, Taylor I, Marchionni L, Raabe E, Eberhart CG, Rodriguez FJ.
    J Neuropathol Exp Neurol; 2015 Feb 15; 74(2):121-31. PubMed ID: 25575134
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of Notch and HIF enhances the antitumor effect of radiation in Notch expressing lung cancer.
    Ikezawa Y, Sakakibara-Konishi J, Mizugaki H, Oizumi S, Nishimura M.
    Int J Clin Oncol; 2017 Feb 15; 22(1):59-69. PubMed ID: 27553958
    [Abstract] [Full Text] [Related]

  • 15. Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells.
    Ponnurangam S, Dandawate PR, Dhar A, Tawfik OW, Parab RR, Mishra PD, Ranadive P, Sharma R, Mahajan G, Umar S, Weir SJ, Sugumar A, Jensen RA, Padhye SB, Balakrishnan A, Anant S, Subramaniam D.
    Oncotarget; 2016 Jan 19; 7(3):3217-32. PubMed ID: 26673007
    [Abstract] [Full Text] [Related]

  • 16. γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancer.
    Mizugaki H, Sakakibara-Konishi J, Ikezawa Y, Kikuchi J, Kikuchi E, Oizumi S, Dang TP, Nishimura M.
    Br J Cancer; 2012 Jun 05; 106(12):1953-9. PubMed ID: 22596234
    [Abstract] [Full Text] [Related]

  • 17. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.
    Saito N, Fu J, Zheng S, Yao J, Wang S, Liu DD, Yuan Y, Sulman EP, Lang FF, Colman H, Verhaak RG, Yung WK, Koul D.
    Stem Cells; 2014 Jan 05; 32(1):301-12. PubMed ID: 24038660
    [Abstract] [Full Text] [Related]

  • 18. Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.
    Tammam J, Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, Hardwick J, Scott M, Winter C, Bristow L, Elbi C, Reilly JF, Look T, Draetta G, Van der Ploeg L, Kohl NE, Strack PR, Majumder PK.
    Br J Pharmacol; 2009 Nov 05; 158(5):1183-95. PubMed ID: 19775282
    [Abstract] [Full Text] [Related]

  • 19. MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma.
    Ramakrishnan V, Ansell S, Haug J, Grote D, Kimlinger T, Stenson M, Timm M, Wellik L, Halling T, Rajkumar SV, Kumar S.
    Leukemia; 2012 Feb 05; 26(2):340-8. PubMed ID: 21826062
    [Abstract] [Full Text] [Related]

  • 20. Notch3 overexpression as potential therapeutic target in advanced stage chemoresistant ovarian cancer.
    Rahman MT, Nakayama K, Rahman M, Katagiri H, Katagiri A, Ishibashi T, Ishikawa M, Iida K, Nakayama S, Otsuki Y, Miyazaki K.
    Am J Clin Pathol; 2012 Oct 05; 138(4):535-44. PubMed ID: 23010708
    [Abstract] [Full Text] [Related]

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