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172 related items for PubMed ID: 17822282
1. Interaction of strong DNA-intercalating bioreductive compounds with topoisomerases I and II. Rosenzweig HS, Papadopoulou MV, Bloomer WD. Oncol Res; 2005; 15(4):219-31. PubMed ID: 17822282 [Abstract] [Full Text] [Related]
2. 9-[3-(2-Nitro-1-imidazolyl)propylamino]-1,2,3,4-tetrahydroacridine hydrochloride. A novel DNA-affinic hypoxic cell cytotoxin and radiosensitizer. Comparison with NLA-1. Papadopoulou MV, Rosenzweig HS, Doddi M, Bloomer WD. Oncol Res; 1994; 6(9):439-48. PubMed ID: 7703530 [Abstract] [Full Text] [Related]
3. AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex. Marshall KM, Holden JA, Koller A, Kashman Y, Copp BR, Barrows LR. Anticancer Drugs; 2004 Oct; 15(9):907-13. PubMed ID: 15457132 [Abstract] [Full Text] [Related]
4. Structural determinants of the catalytic inhibition of human topoisomerase IIα by salicylate analogs and salicylate-based drugs. Bau JT, Kurz EU. Biochem Pharmacol; 2014 Jun 15; 89(4):464-76. PubMed ID: 24695359 [Abstract] [Full Text] [Related]
5. Topoisomerase II-mediated DNA cleavage activity and irreversibility of cleavable complex formation induced by DNA intercalator with alkylating capability. Kong XB, Rubin L, Chen LI, Ciszewska G, Watanabe KA, Tong WP, Sirotnak FM, Chou TC. Mol Pharmacol; 1992 Feb 15; 41(2):237-44. PubMed ID: 1311406 [Abstract] [Full Text] [Related]
6. Berenil acts as a poison of eukaryotic topoisomerase II. Portugal J. FEBS Lett; 1994 May 16; 344(2-3):136-8. PubMed ID: 8187871 [Abstract] [Full Text] [Related]
7. DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition. Fortune JM, Velea L, Graves DE, Utsugi T, Yamada Y, Osheroff N. Biochemistry; 1999 Nov 23; 38(47):15580-6. PubMed ID: 10569942 [Abstract] [Full Text] [Related]
8. A cisplatin-resistant murine leukemia cell line exhibits increased topoisomerase II activity. Barret JM, Calsou P, Larsen AK, Salles B. Mol Pharmacol; 1994 Sep 23; 46(3):431-6. PubMed ID: 7935322 [Abstract] [Full Text] [Related]
9. Molecular interactions of DNA-topoisomerase I and II inhibitor with DNA and topoisomerases and in ternary complexes: binding modes and biological effects for intoplicine derivatives. Nabiev I, Chourpa I, Riou JF, Nguyen CH, Lavelle F, Manfait M. Biochemistry; 1994 Aug 02; 33(30):9013-23. PubMed ID: 8043587 [Abstract] [Full Text] [Related]
10. Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity. Nunhart P, Konkoľová E, Janovec L, Jendželovský R, Vargová J, Ševc J, Matejová M, Miltáková B, Fedoročko P, Kozurkova M. Bioorg Chem; 2020 Jan 02; 94():103393. PubMed ID: 31679839 [Abstract] [Full Text] [Related]
11. The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II. Larsen AK, Grondard L, Couprie J, Desoize B, Comoe L, Jardillier JC, Riou JF. Biochem Pharmacol; 1993 Oct 19; 46(8):1403-12. PubMed ID: 8240389 [Abstract] [Full Text] [Related]
12. An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2, 1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells. Padget K, Stewart A, Charlton P, Tilby MJ, Austin CA. Biochem Pharmacol; 2000 Sep 15; 60(6):817-21. PubMed ID: 10930536 [Abstract] [Full Text] [Related]
13. Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds. Janočková J, Plšíková J, Kašpárková J, Brabec V, Jendželovský R, Mikeš J, Kovaľ J, Hamuľaková S, Fedoročko P, Kuča K, Kožurková M. Eur J Pharm Sci; 2015 Aug 30; 76():192-202. PubMed ID: 25960253 [Abstract] [Full Text] [Related]
14. Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: a mechanism for the apparent intercalator-induced inhibition of topoisomerase II. McDonald LA, Eldredge GS, Barrows LR, Ireland CM. J Med Chem; 1994 Oct 28; 37(22):3819-27. PubMed ID: 7525959 [Abstract] [Full Text] [Related]
15. Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs. Salerno S, Da Settimo F, Taliani S, Simorini F, La Motta C, Fornaciari G, Marini AM. Curr Med Chem; 2010 Oct 28; 17(35):4270-90. PubMed ID: 20939813 [Abstract] [Full Text] [Related]
16. Inhibitory properties of antitumor prostaglandins against topoisomerases. Suzuki K, Uyeda M. Biosci Biotechnol Biochem; 2002 Aug 28; 66(8):1706-12. PubMed ID: 12353631 [Abstract] [Full Text] [Related]
17. Inhibition of DNA topoisomerases II and/or I by pyrazolo[1,5-a]indole derivatives and their growth inhibitory activities. Umemura K, Mizushima T, Katayama H, Kiryu Y, Yamori T, Andoh T. Mol Pharmacol; 2002 Oct 28; 62(4):873-80. PubMed ID: 12237334 [Abstract] [Full Text] [Related]
18. Comparative analysis of topoisomerase IB inhibition and DNA intercalation by flavonoids and similar compounds: structural determinates of activity. Webb MR, Ebeler SE. Biochem J; 2004 Dec 15; 384(Pt 3):527-41. PubMed ID: 15312049 [Abstract] [Full Text] [Related]
19. A unique paclitaxel-mediated modulation of the catalytic activity of topoisomerase IIalpha. Dhawan V, Swaffar DS. Anticancer Drugs; 1999 Apr 15; 10(4):397-404. PubMed ID: 10378675 [Abstract] [Full Text] [Related]
20. DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors. Chen AY, Yu C, Gatto B, Liu LF. Proc Natl Acad Sci U S A; 1993 Sep 01; 90(17):8131-5. PubMed ID: 7690143 [Abstract] [Full Text] [Related] Page: [Next] [New Search]