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236 related items for PubMed ID: 17825569

  • 1. The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
    Paluchowska MH, Bugno R, Duszyńska B, Tatarczyńska E, Nikiforuk A, Lenda T, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2007 Nov 15; 15(22):7116-25. PubMed ID: 17825569
    [Abstract] [Full Text] [Related]

  • 2. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2005 Mar 15; 13(6):2293-303. PubMed ID: 15727878
    [Abstract] [Full Text] [Related]

  • 3. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D.
    J Med Chem; 2004 May 06; 47(10):2659-66. PubMed ID: 15115407
    [Abstract] [Full Text] [Related]

  • 4. Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.
    Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E, Pawłowski M, Martinez J.
    Bioorg Med Chem; 2007 Apr 15; 15(8):2907-19. PubMed ID: 17321139
    [Abstract] [Full Text] [Related]

  • 5. Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Bugno R, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2006 Mar 01; 14(5):1391-402. PubMed ID: 16266808
    [Abstract] [Full Text] [Related]

  • 6. Influence of the aliphatic spacer length on the 5-HT1A receptor activity of new arylpiperazines with an indazole system.
    Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E.
    Pol J Pharmacol; 2000 Mar 01; 52(3):209-16. PubMed ID: 11055578
    [Abstract] [Full Text] [Related]

  • 7. New 4-[omega-(diarylmethylamino)alkyl]- and 4-[omega-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1A/5-HT2A receptor ligands with differentiated in vivo activity.
    Paluchowska MH, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Stachowicz K, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2004 Mar 01; 56(6):743-54. PubMed ID: 15662087
    [Abstract] [Full Text] [Related]

  • 8. Some pharmacological properties of new analogs of MP 3022, the 5-HT1A receptor antagonist.
    Chojnacka-Wójcik E, Kłodzińska A, Tatarczyńska E, Paluchowska MH.
    Pol J Pharmacol; 1999 Mar 01; 51(5):405-13. PubMed ID: 10817541
    [Abstract] [Full Text] [Related]

  • 9. 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
    Chłoń-Rzepa G, Zmudzki P, Zajdel P, Bojarski AJ, Duszyńska B, Nikiforuk A, Tatarczyńska E, Pawłowski M.
    Bioorg Med Chem; 2007 Aug 01; 15(15):5239-50. PubMed ID: 17517514
    [Abstract] [Full Text] [Related]

  • 10. Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity.
    Paluchowska MH, Mokrosz MJ, Charakchieva-Minol S, Duszyńska B, Kozioł A, Wesołowska A, Stachowicz K, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2003 Aug 01; 55(4):543-52. PubMed ID: 14581712
    [Abstract] [Full Text] [Related]

  • 11. Conformational restriction in novel NAN-190 and MP3022 analogs and their 5-HT(1A) receptor activity.
    Paluchowska MH, Bugno R, Charakchieva-Minol S, Bojarski AJ, Tatarczyńska E, Chojnacka-Wójcik E.
    Arch Pharm (Weinheim); 2006 Sep 01; 339(9):498-506. PubMed ID: 16941730
    [Abstract] [Full Text] [Related]

  • 12. Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Perrone R, Tortorella V.
    J Pharm Pharmacol; 2004 Feb 01; 56(2):247-55. PubMed ID: 15005884
    [Abstract] [Full Text] [Related]

  • 13. 'Click' D(1) receptor agonists with a 5-HT(1A) receptor pharmacophore producing D(2) receptor activity.
    Zhang J, Zhang H, Cai W, Yu L, Zhen X, Zhang A.
    Bioorg Med Chem; 2009 Jul 15; 17(14):4873-80. PubMed ID: 19559623
    [Abstract] [Full Text] [Related]

  • 14. Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist.
    Picard M, Morisset S, Cloix JF, Bizot JC, Guerin M, Beneteau V, Guillaumet G, Hevor TK.
    Neuroscience; 2010 Sep 01; 169(3):1337-46. PubMed ID: 20580787
    [Abstract] [Full Text] [Related]

  • 15. 1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors.
    Sorbi C, Franchini S, Tait A, Prandi A, Gallesi R, Angeli P, Marucci G, Pirona L, Poggesi E, Brasili L.
    ChemMedChem; 2009 Mar 01; 4(3):393-9. PubMed ID: 19152363
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.
    López-Rodríguez ML, Morcillo MJ, Fernández E, Benhamú B, Tejada I, Ayala D, Viso A, Campillo M, Pardo L, Delgado M, Manzanares J, Fuentes JA.
    J Med Chem; 2005 Apr 07; 48(7):2548-58. PubMed ID: 15801844
    [Abstract] [Full Text] [Related]

  • 17. Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.
    López-Rodríguez ML, Benhamú B, Morcillo MJ, Tejada I, Avila D, Marco I, Schiapparelli L, Frechilla D, Del Río J.
    Bioorg Med Chem; 2004 Oct 01; 12(19):5181-91. PubMed ID: 15351401
    [Abstract] [Full Text] [Related]

  • 18. 1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.
    Franchini S, Prandi A, Baraldi A, Sorbi C, Tait A, Buccioni M, Marucci G, Cilia A, Pirona L, Fossa P, Cichero E, Brasili L.
    Eur J Med Chem; 2010 Sep 01; 45(9):3740-51. PubMed ID: 20605276
    [Abstract] [Full Text] [Related]

  • 19. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity.
    Czopek A, Byrtus H, Kołaczkowski M, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Wesołowska A, Chojnacka-Wójcik E.
    Eur J Med Chem; 2010 Apr 16; 45(4):1295-303. PubMed ID: 20060623
    [Abstract] [Full Text] [Related]

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