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Journal Abstract Search


480 related items for PubMed ID: 17848099

  • 1. Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.
    Thomson JM, Distler AM, Bonomo RA.
    Biochemistry; 2007 Oct 09; 46(40):11361-8. PubMed ID: 17848099
    [Abstract] [Full Text] [Related]

  • 2. X-ray structure of the Asn276Asp variant of the Escherichia coli TEM-1 beta-lactamase: direct observation of electrostatic modulation in resistance to inactivation by clavulanic acid.
    Swarén P, Golemi D, Cabantous S, Bulychev A, Maveyraud L, Mobashery S, Samama JP.
    Biochemistry; 1999 Jul 27; 38(30):9570-6. PubMed ID: 10423234
    [Abstract] [Full Text] [Related]

  • 3. Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance.
    Li M, Conklin BC, Taracila MA, Hutton RA, Skalweit MJ.
    Antimicrob Agents Chemother; 2012 Nov 27; 56(11):5678-86. PubMed ID: 22908166
    [Abstract] [Full Text] [Related]

  • 4. Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.
    Papp-Wallace KM, Bethel CR, Distler AM, Kasuboski C, Taracila M, Bonomo RA.
    Antimicrob Agents Chemother; 2010 Feb 27; 54(2):890-7. PubMed ID: 20008772
    [Abstract] [Full Text] [Related]

  • 5. Probing active site chemistry in SHV beta-lactamase variants at Ambler position 244. Understanding unique properties of inhibitor resistance.
    Thomson JM, Distler AM, Prati F, Bonomo RA.
    J Biol Chem; 2006 Sep 08; 281(36):26734-44. PubMed ID: 16803899
    [Abstract] [Full Text] [Related]

  • 6. Comparative evaluation of the in vitro activity of three combinations of beta-lactams with beta-lactamase inhibitors: piperacillin/tazobactam, ticarcillin/clavulanic acid and ampicillin/sulbactam.
    Sader HS, Tosin I, Sejas L, Miranda E.
    Braz J Infect Dis; 2000 Feb 08; 4(1):22-8. PubMed ID: 10788842
    [Abstract] [Full Text] [Related]

  • 7. Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition.
    Sulton D, Pagan-Rodriguez D, Zhou X, Liu Y, Hujer AM, Bethel CR, Helfand MS, Thomson JM, Anderson VE, Buynak JD, Ng LM, Bonomo RA.
    J Biol Chem; 2005 Oct 21; 280(42):35528-36. PubMed ID: 15987690
    [Abstract] [Full Text] [Related]

  • 8. Effect of beta-lactamase inhibitors on minimum inhibitory concentration of ampicillin and amoxicillin for Staphylococcus aureus strains.
    Paniagua GL, Monroy E, García O, Vaca S.
    Rev Latinoam Microbiol; 1998 Oct 21; 40(3-4):128-34. PubMed ID: 10932741
    [Abstract] [Full Text] [Related]

  • 9. Kinetic analysis of an inhibitor-resistant variant of the OHIO-1 beta-lactamase, an SHV-family class A enzyme.
    Lin S, Thomas M, Shlaes DM, Rudin SD, Knox JR, Anderson V, Bonomo RA.
    Biochem J; 1998 Jul 15; 333 ( Pt 2)(Pt 2):395-400. PubMed ID: 9735103
    [Abstract] [Full Text] [Related]

  • 10. The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.
    Drawz SM, Bethel CR, Hujer KM, Hurless KN, Distler AM, Caselli E, Prati F, Bonomo RA.
    Biochemistry; 2009 Jun 02; 48(21):4557-66. PubMed ID: 19351161
    [Abstract] [Full Text] [Related]

  • 11. Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanic acid and sulbactam combined with ampicillin and piperacillin against beta-lactamase producing anaerobic bacteria.
    Nord CE.
    J Chemother; 1989 Jul 02; 1(4 Suppl):273-5. PubMed ID: 16312398
    [No Abstract] [Full Text] [Related]

  • 12. beta-Lactam resistance phenotype determination in Escherichia coli isolates from University Malaya Medical Centre.
    Wong JS, Mohd Azri ZA, Subramaniam G, Ho SE, Palasubramaniam S, Navaratnam P.
    Malays J Pathol; 2003 Dec 02; 25(2):113-9. PubMed ID: 16196367
    [Abstract] [Full Text] [Related]

  • 13. In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes.
    Mushtaq S, Warner M, Ge Y, Kaniga K, Livermore DM.
    J Antimicrob Chemother; 2007 Aug 02; 60(2):300-11. PubMed ID: 17548456
    [Abstract] [Full Text] [Related]

  • 14. Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems.
    Bethel CR, Taracila M, Shyr T, Thomson JM, Distler AM, Hujer KM, Hujer AM, Endimiani A, Papp-Wallace K, Bonnet R, Bonomo RA.
    Antimicrob Agents Chemother; 2011 Jul 02; 55(7):3465-75. PubMed ID: 21555770
    [Abstract] [Full Text] [Related]

  • 15. Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130.
    Helfand MS, Bethel CR, Hujer AM, Hujer KM, Anderson VE, Bonomo RA.
    J Biol Chem; 2003 Dec 26; 278(52):52724-9. PubMed ID: 14534312
    [Abstract] [Full Text] [Related]

  • 16. Aspartic acid for asparagine substitution at position 276 reduces susceptibility to mechanism-based inhibitors in SHV-1 and SHV-5 beta-lactamases.
    Giakkoupi P, Tzelepi E, Legakis NJ, Tzouvelekis LS.
    J Antimicrob Chemother; 1999 Jan 26; 43(1):23-9. PubMed ID: 10381097
    [Abstract] [Full Text] [Related]

  • 17. Correlation of in vitro susceptibility testing results for amoxicillin-clavulanate and ampicillin-sulbactam using a panel of beta-lactamase-producing Enterobacteriaceae.
    Siu LK, Cheng WL, Ho PL, Ng WS, Chau PY, Lo JY.
    APMIS; 1998 Sep 26; 106(9):917-20. PubMed ID: 9808419
    [Abstract] [Full Text] [Related]

  • 18. Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography.
    Helfand MS, Totir MA, Carey MP, Hujer AM, Bonomo RA, Carey PR.
    Biochemistry; 2003 Nov 25; 42(46):13386-92. PubMed ID: 14621983
    [Abstract] [Full Text] [Related]

  • 19. OHIO-1 beta-lactamase mutants: the Arg244Ser mutant and resistance to beta-lactams and beta-lactamase inhibitors.
    Lin S, Thomas M, Mark S, Anderson V, Bonomo RA.
    Biochim Biophys Acta; 1999 Jun 15; 1432(1):125-36. PubMed ID: 10366735
    [Abstract] [Full Text] [Related]

  • 20. Hyperproduction of inhibitor-susceptible TEM beta-lactamase is responsible for resistance of Serratia marcescens to beta-lactam-beta-lactamase inhibitor combinations.
    Zhao WH, Hu ZQ, Chen G, Ito R, Shimamura T.
    Chemotherapy; 2008 Jun 15; 54(1):31-7. PubMed ID: 18063864
    [Abstract] [Full Text] [Related]


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