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469 related items for PubMed ID: 17849451
1. TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR. Golubovskaya VM, Virnig C, Cance WG. Mol Carcinog; 2008 Mar; 47(3):222-34. PubMed ID: 17849451 [Abstract] [Full Text] [Related]
2. Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines. Golubovskaya VM, Gross S, Kaur AS, Wilson RI, Xu LH, Yang XH, Cance WG. Mol Cancer Res; 2003 Aug; 1(10):755-64. PubMed ID: 12939401 [Abstract] [Full Text] [Related]
3. Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-I receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo. Watanabe N, Takaoka M, Sakurama K, Tomono Y, Hatakeyama S, Ohmori O, Motoki T, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Beer DG, Nagatsuka H, Tanaka N, Naomoto Y. Clin Cancer Res; 2008 Jul 15; 14(14):4631-9. PubMed ID: 18628478 [Abstract] [Full Text] [Related]
4. A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. Shi Q, Hjelmeland AB, Keir ST, Song L, Wickman S, Jackson D, Ohmori O, Bigner DD, Friedman HS, Rich JN. Mol Carcinog; 2007 Jun 15; 46(6):488-96. PubMed ID: 17219439 [Abstract] [Full Text] [Related]
5. Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo. Kurio N, Shimo T, Fukazawa T, Takaoka M, Okui T, Hassan NM, Honami T, Hatakeyama S, Ikeda M, Naomoto Y, Sasaki A. Exp Cell Res; 2011 May 01; 317(8):1134-46. PubMed ID: 21338601 [Abstract] [Full Text] [Related]
6. TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. Wang ZG, Fukazawa T, Nishikawa T, Watanabe N, Sakurama K, Motoki T, Takaoka M, Hatakeyama S, Omori O, Ohara T, Tanabe S, Fujiwara Y, Shirakawa Y, Yamatsuji T, Tanaka N, Naomoto Y. Oncol Rep; 2008 Dec 01; 20(6):1473-7. PubMed ID: 19020730 [Abstract] [Full Text] [Related]
7. 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226. Hehlgans S, Lange I, Eke I, Cordes N. Radiother Oncol; 2009 Sep 01; 92(3):371-8. PubMed ID: 19729215 [Abstract] [Full Text] [Related]
8. Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. Payne SL, Fogelgren B, Hess AR, Seftor EA, Wiley EL, Fong SF, Csiszar K, Hendrix MJ, Kirschmann DA. Cancer Res; 2005 Dec 15; 65(24):11429-36. PubMed ID: 16357151 [Abstract] [Full Text] [Related]
9. Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer. Planas-Silva MD, Bruggeman RD, Grenko RT, Stanley Smith J. Biochem Biophys Res Commun; 2006 Mar 03; 341(1):73-81. PubMed ID: 16412380 [Abstract] [Full Text] [Related]
10. Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells. Garces CA, Kurenova EV, Golubovskaya VM, Cance WG. Cancer Res; 2006 Feb 01; 66(3):1446-54. PubMed ID: 16452200 [Abstract] [Full Text] [Related]
11. Activated Src increases adhesion, survival and alpha2-integrin expression in human breast cancer cells. Park HB, Golubovskaya V, Xu L, Yang X, Lee JW, Scully S, Craven RJ, Cance WG. Biochem J; 2004 Mar 01; 378(Pt 2):559-67. PubMed ID: 14629195 [Abstract] [Full Text] [Related]
12. Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma. Madan R, Smolkin MB, Cocker R, Fayyad R, Oktay MH. Hum Pathol; 2006 Jan 01; 37(1):9-15. PubMed ID: 16360410 [Abstract] [Full Text] [Related]
13. Overexpression of RhoA-GTP induces activation of the Epidermal Growth Factor Receptor, dephosphorylation of focal adhesion kinase and increased motility in breast cancer cells. Cáceres M, Guerrero J, Martínez J. Exp Cell Res; 2005 Sep 10; 309(1):229-38. PubMed ID: 15963982 [Abstract] [Full Text] [Related]
14. Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway. Cowell LN, Graham JD, Bouton AH, Clarke CL, O'Neill GM. Oncogene; 2006 Dec 07; 25(58):7597-607. PubMed ID: 16799644 [Abstract] [Full Text] [Related]
15. Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells. Hochgräfe F, Zhang L, O'Toole SA, Browne BC, Pinese M, Porta Cubas A, Lehrbach GM, Croucher DR, Rickwood D, Boulghourjian A, Shearer R, Nair R, Swarbrick A, Faratian D, Mullen P, Harrison DJ, Biankin AV, Sutherland RL, Raftery MJ, Daly RJ. Cancer Res; 2010 Nov 15; 70(22):9391-401. PubMed ID: 20861192 [Abstract] [Full Text] [Related]
16. Src and FAK mediate cell-matrix adhesion-dependent activation of Met during transformation of breast epithelial cells. Hui AY, Meens JA, Schick C, Organ SL, Qiao H, Tremblay EA, Schaeffer E, Uniyal S, Chan BM, Elliott BE. J Cell Biochem; 2009 Aug 15; 107(6):1168-81. PubMed ID: 19533669 [Abstract] [Full Text] [Related]
17. Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells. Golubovskaya V, Beviglia L, Xu LH, Earp HS, Craven R, Cance W. J Biol Chem; 2002 Oct 11; 277(41):38978-87. PubMed ID: 12167618 [Abstract] [Full Text] [Related]
18. Src family kinases and HER2 interactions in human breast cancer cell growth and survival. Belsches-Jablonski AP, Biscardi JS, Peavy DR, Tice DA, Romney DA, Parsons SJ. Oncogene; 2001 Mar 22; 20(12):1465-75. PubMed ID: 11313890 [Abstract] [Full Text] [Related]
19. Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2. Khare S, Holgren C, Samarel AM. Am J Physiol Gastrointest Liver Physiol; 2006 Dec 22; 291(6):G1100-12. PubMed ID: 16920701 [Abstract] [Full Text] [Related]
20. Inhibitory role of focal adhesion kinase on anoikis in the lung cancer cell A549. Liu G, Meng X, Jin Y, Bai J, Zhao Y, Cui X, Chen F, Fu S. Cell Biol Int; 2008 Jun 22; 32(6):663-70. PubMed ID: 18343694 [Abstract] [Full Text] [Related] Page: [Next] [New Search]