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226 related items for PubMed ID: 17854868

  • 1. Late sodium current in failing heart: friend or foe?
    Maltsev VA, Undrovinas A.
    Prog Biophys Mol Biol; 2008; 96(1-3):421-51. PubMed ID: 17854868
    [Abstract] [Full Text] [Related]

  • 2. Late sodium current is a new therapeutic target to improve contractility and rhythm in failing heart.
    Undrovinas A, Maltsev VA.
    Cardiovasc Hematol Agents Med Chem; 2008 Oct; 6(4):348-59. PubMed ID: 18855648
    [Abstract] [Full Text] [Related]

  • 3. Contribution of sodium channel neuronal isoform Nav1.1 to late sodium current in ventricular myocytes from failing hearts.
    Mishra S, Reznikov V, Maltsev VA, Undrovinas NA, Sabbah HN, Undrovinas A.
    J Physiol; 2015 Mar 15; 593(6):1409-27. PubMed ID: 25772296
    [Abstract] [Full Text] [Related]

  • 4. Gating of the late Na+ channel in normal and failing human myocardium.
    Undrovinas AI, Maltsev VA, Kyle JW, Silverman N, Sabbah HN.
    J Mol Cell Cardiol; 2002 Nov 15; 34(11):1477-89. PubMed ID: 12431447
    [Abstract] [Full Text] [Related]

  • 5. A multi-modal composition of the late Na+ current in human ventricular cardiomyocytes.
    Maltsev VA, Undrovinas AI.
    Cardiovasc Res; 2006 Jan 15; 69(1):116-27. PubMed ID: 16223473
    [Abstract] [Full Text] [Related]

  • 6. Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart.
    Dybkova N, Ahmad S, Pabel S, Tirilomis P, Hartmann N, Fischer TH, Bengel P, Tirilomis T, Ljubojevic S, Renner A, Gummert J, Ellenberger D, Wagner S, Frey N, Maier LS, Streckfuss-Bömeke K, Hasenfuss G, Sossalla S.
    Cardiovasc Res; 2018 Nov 01; 114(13):1728-1737. PubMed ID: 29931291
    [Abstract] [Full Text] [Related]

  • 7. Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytes.
    Maltsev VA, Sabbah HN, Higgins RS, Silverman N, Lesch M, Undrovinas AI.
    Circulation; 1998 Dec 08; 98(23):2545-52. PubMed ID: 9843461
    [Abstract] [Full Text] [Related]

  • 8. Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.
    Maltsev VA, Silverman N, Sabbah HN, Undrovinas AI.
    Eur J Heart Fail; 2007 Mar 08; 9(3):219-27. PubMed ID: 17067855
    [Abstract] [Full Text] [Related]

  • 9. Late Na+ current produced by human cardiac Na+ channel isoform Nav1.5 is modulated by its beta1 subunit.
    Maltsev VA, Kyle JW, Undrovinas A.
    J Physiol Sci; 2009 May 08; 59(3):217-25. PubMed ID: 19340536
    [Abstract] [Full Text] [Related]

  • 10. Drug potency on inhibiting late Na+ current is sensitive to gating modifier and current region where drug effects were measured.
    Wu M, Tran PN, Sheng J, Randolph AL, Wu WW.
    J Pharmacol Toxicol Methods; 2019 May 08; 100():106605. PubMed ID: 31255744
    [Abstract] [Full Text] [Related]

  • 11. Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences.
    Maltsev VA, Reznikov V, Undrovinas NA, Sabbah HN, Undrovinas A.
    Am J Physiol Heart Circ Physiol; 2008 Apr 08; 294(4):H1597-608. PubMed ID: 18203851
    [Abstract] [Full Text] [Related]

  • 12. Contribution of the neuronal sodium channel NaV1.8 to sodium- and calcium-dependent cellular proarrhythmia.
    Bengel P, Ahmad S, Tirilomis P, Trum M, Dybkova N, Wagner S, Maier LS, Hasenfuß G, Sossalla S.
    J Mol Cell Cardiol; 2020 Jul 08; 144():35-46. PubMed ID: 32418916
    [Abstract] [Full Text] [Related]

  • 13. β-adrenergic regulation of late Na+ current during cardiac action potential is mediated by both PKA and CaMKII.
    Hegyi B, Bányász T, Izu LT, Belardinelli L, Bers DM, Chen-Izu Y.
    J Mol Cell Cardiol; 2018 Oct 08; 123():168-179. PubMed ID: 30240676
    [Abstract] [Full Text] [Related]

  • 14. Calpain inhibition reduces amplitude and accelerates decay of the late sodium current in ventricular myocytes from dogs with chronic heart failure.
    Undrovinas A, Maltsev VA, Sabbah HN.
    PLoS One; 2013 Oct 08; 8(4):e54436. PubMed ID: 23596505
    [Abstract] [Full Text] [Related]

  • 15. Late sodium current associated cardiac electrophysiological and mechanical dysfunction.
    Yu S, Li G, Huang CL, Lei M, Wu L.
    Pflugers Arch; 2018 Mar 08; 470(3):461-469. PubMed ID: 29127493
    [Abstract] [Full Text] [Related]

  • 16. A computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na+ current.
    Yang PC, Song Y, Giles WR, Horvath B, Chen-Izu Y, Belardinelli L, Rajamani S, Clancy CE.
    J Physiol; 2015 Mar 15; 593(6):1429-42. PubMed ID: 25545172
    [Abstract] [Full Text] [Related]

  • 17. Thyroid Hormone Diminishes Ca2+ Overload Induced by Hypoxia/Reoxygenation in Cardiomyocytes by Inhibiting Late Sodium Current and Reverse-Na+/Ca2+ Exchange Current.
    Zeng B, Liao X, Liu L, Ruan H, Zhang C.
    Pharmacology; 2020 Mar 15; 105(1-2):63-72. PubMed ID: 31514184
    [Abstract] [Full Text] [Related]

  • 18. Post-transcriptional alterations in the expression of cardiac Na+ channel subunits in chronic heart failure.
    Zicha S, Maltsev VA, Nattel S, Sabbah HN, Undrovinas AI.
    J Mol Cell Cardiol; 2004 Jul 15; 37(1):91-100. PubMed ID: 15242739
    [Abstract] [Full Text] [Related]

  • 19. Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure.
    Bengel P, Dybkova N, Tirilomis P, Ahmad S, Hartmann N, A Mohamed B, Krekeler MC, Maurer W, Pabel S, Trum M, Mustroph J, Gummert J, Milting H, Wagner S, Ljubojevic-Holzer S, Toischer K, Maier LS, Hasenfuss G, Streckfuss-Bömeke K, Sossalla S.
    Nat Commun; 2021 Nov 15; 12(1):6586. PubMed ID: 34782600
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of late Na+ current, a novel target to improve diastolic function and electrical abnormalities in Dahl salt-sensitive rats.
    Chi L, Belardinelli L, Zeng A, Hirakawa R, Rajamani S, Ling H, Dhalla AK.
    Am J Physiol Heart Circ Physiol; 2016 May 15; 310(10):H1313-20. PubMed ID: 26993228
    [Abstract] [Full Text] [Related]


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