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158 related items for PubMed ID: 17869249

  • 1. The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells.
    Dimopoulos N, Watson M, Green C, Hundal HS.
    FEBS Lett; 2007 Oct 02; 581(24):4743-8. PubMed ID: 17869249
    [Abstract] [Full Text] [Related]

  • 2. Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells.
    Coll T, Alvarez-Guardia D, Barroso E, Gómez-Foix AM, Palomer X, Laguna JC, Vázquez-Carrera M.
    Endocrinology; 2010 Apr 02; 151(4):1560-9. PubMed ID: 20185762
    [Abstract] [Full Text] [Related]

  • 3. Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle.
    Krämer DK, Al-Khalili L, Guigas B, Leng Y, Garcia-Roves PM, Krook A.
    J Biol Chem; 2007 Jul 06; 282(27):19313-20. PubMed ID: 17500064
    [Abstract] [Full Text] [Related]

  • 4. Angiopoietin-like 4 mediates PPAR delta effect on lipoprotein lipase-dependent fatty acid uptake but not on beta-oxidation in myotubes.
    Robciuc MR, Skrobuk P, Anisimov A, Olkkonen VM, Alitalo K, Eckel RH, Koistinen HA, Jauhiainen M, Ehnholm C.
    PLoS One; 2012 Jul 06; 7(10):e46212. PubMed ID: 23056264
    [Abstract] [Full Text] [Related]

  • 5. Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.
    Krämer DK, Al-Khalili L, Perrini S, Skogsberg J, Wretenberg P, Kannisto K, Wallberg-Henriksson H, Ehrenborg E, Zierath JR, Krook A.
    Diabetes; 2005 Apr 06; 54(4):1157-63. PubMed ID: 15793256
    [Abstract] [Full Text] [Related]

  • 6. PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.
    Feng YZ, Nikolić N, Bakke SS, Boekschoten MV, Kersten S, Kase ET, Rustan AC, Thoresen GH.
    Arch Physiol Biochem; 2014 Feb 06; 120(1):12-21. PubMed ID: 23991827
    [Abstract] [Full Text] [Related]

  • 7. Dissociation between PGC-1alpha and GLUT-4 expression in skeletal muscle of rats fed a high-fat diet.
    Higashida K, Higuchi M, Terada S.
    J Nutr Sci Vitaminol (Tokyo); 2009 Dec 06; 55(6):486-91. PubMed ID: 20086318
    [Abstract] [Full Text] [Related]

  • 8. Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats.
    Benton CR, Holloway GP, Han XX, Yoshida Y, Snook LA, Lally J, Glatz JF, Luiken JJ, Chabowski A, Bonen A.
    Diabetologia; 2010 Sep 06; 53(9):2008-19. PubMed ID: 20490453
    [Abstract] [Full Text] [Related]

  • 9. Genistein stimulates fatty acid oxidation in a leptin receptor-independent manner through the JAK2-mediated phosphorylation and activation of AMPK in skeletal muscle.
    Palacios-González B, Zarain-Herzberg A, Flores-Galicia I, Noriega LG, Alemán-Escondrillas G, Zariñan T, Ulloa-Aguirre A, Torres N, Tovar AR.
    Biochim Biophys Acta; 2014 Jan 06; 1841(1):132-40. PubMed ID: 24013029
    [Abstract] [Full Text] [Related]

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  • 11. Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.
    Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J.
    Proc Natl Acad Sci U S A; 2003 Dec 23; 100(26):15924-9. PubMed ID: 14676330
    [Abstract] [Full Text] [Related]

  • 12. Oral administration of a PPAR-delta agonist to rodents worsens, not improves, maximal insulin-stimulated glucose transport in skeletal muscle of different fibers.
    Cresser J, Bonen A, Chabowski A, Stefanyk LE, Gulli R, Ritchie I, Dyck DJ.
    Am J Physiol Regul Integr Comp Physiol; 2010 Aug 23; 299(2):R470-9. PubMed ID: 20538899
    [Abstract] [Full Text] [Related]

  • 13. PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle.
    Ye JM, Tid-Ang J, Turner N, Zeng XY, Li HY, Cooney GJ, Wulff EM, Sauerberg P, Kraegen EW.
    Br J Pharmacol; 2011 Jun 23; 163(3):556-66. PubMed ID: 21265823
    [Abstract] [Full Text] [Related]

  • 14. PPARdelta activator GW-501516 has no acute effect on glucose transport in skeletal muscle.
    Terada S, Wicke S, Holloszy JO, Han DH.
    Am J Physiol Endocrinol Metab; 2006 Apr 23; 290(4):E607-11. PubMed ID: 16278250
    [Abstract] [Full Text] [Related]

  • 15. Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity.
    Klingler C, Zhao X, Adhikary T, Li J, Xu G, Häring HU, Schleicher E, Lehmann R, Weigert C.
    Biochim Biophys Acta; 2016 Dec 23; 1861(12 Pt A):1980-1992. PubMed ID: 27697477
    [Abstract] [Full Text] [Related]

  • 16. Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist.
    Sprecher DL, Massien C, Pearce G, Billin AN, Perlstein I, Willson TM, Hassall DG, Ancellin N, Patterson SD, Lobe DC, Johnson TG.
    Arterioscler Thromb Vasc Biol; 2007 Feb 23; 27(2):359-65. PubMed ID: 17110604
    [Abstract] [Full Text] [Related]

  • 17. In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor δ reflects donors' insulin sensitivity in vivo.
    Ordelheide AM, Heni M, Thamer C, Machicao F, Fritsche A, Stefan N, Häring HU, Staiger H.
    Eur J Clin Invest; 2011 Dec 23; 41(12):1323-9. PubMed ID: 21615395
    [Abstract] [Full Text] [Related]

  • 18. Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle.
    Al-Khalili L, Bouzakri K, Glund S, Lönnqvist F, Koistinen HA, Krook A.
    Mol Endocrinol; 2006 Dec 23; 20(12):3364-75. PubMed ID: 16945991
    [Abstract] [Full Text] [Related]

  • 19. The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells.
    Dressel U, Allen TL, Pippal JB, Rohde PR, Lau P, Muscat GE.
    Mol Endocrinol; 2003 Dec 23; 17(12):2477-93. PubMed ID: 14525954
    [Abstract] [Full Text] [Related]

  • 20. Genetic downregulation of receptor-interacting protein 140 uncovers the central role of Akt signalling in the regulation of fatty acid oxidation in skeletal muscle cells.
    Constantinescu S, Turcotte LP.
    Exp Physiol; 2013 Feb 23; 98(2):514-25. PubMed ID: 22923231
    [Abstract] [Full Text] [Related]

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