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Journal Abstract Search

389 related items for PubMed ID: 17881660

  • 21. Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells.
    Fedejko-Kap B, Niemira M, Radominska-Pandya A, Mazerska Z.
    Xenobiotica; 2011 Dec; 41(12):1044-55. PubMed ID: 21859392
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  • 22. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC, Wallace AD, Hodgson E, Rose RL.
    Drug Metab Dispos; 2006 Oct; 34(10):1779-85. PubMed ID: 16855053
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  • 23. Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes.
    Shiraga T, Kaneko H, Iwasaki K, Tozuka Z, Suzuki A, Hata T.
    Xenobiotica; 1999 Mar; 29(3):217-29. PubMed ID: 10219963
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  • 24. Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.
    Rehmel JL, Eckstein JA, Farid NA, Heim JB, Kasper SC, Kurihara A, Wrighton SA, Ring BJ.
    Drug Metab Dispos; 2006 Apr; 34(4):600-7. PubMed ID: 16415119
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  • 25. Inhibition of the microsomal N-hydroxylation of 2-amino-6-nitrotoluene by a metabolite of methimazole.
    Kedderis GL, Rickert DE.
    Biochem Biophys Res Commun; 1983 Jun 15; 113(2):433-8. PubMed ID: 6870866
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  • 28. Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine--a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays.
    Noronha G, Barrett K, Boccia A, Brodhag T, Cao J, Chow CP, Dneprovskaia E, Doukas J, Fine R, Gong X, Gritzen C, Gu H, Hanna E, Hood JD, Hu S, Kang X, Key J, Klebansky B, Kousba A, Li G, Lohse D, Mak CC, McPherson A, Palanki MS, Pathak VP, Renick J, Shi F, Soll R, Splittgerber U, Stoughton S, Tang S, Yee S, Zeng B, Zhao N, Zhu H.
    Bioorg Med Chem Lett; 2007 Feb 01; 17(3):602-8. PubMed ID: 17113292
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  • 29. Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.
    Chung WG, Park CS, Roh HK, Lee WK, Cha YN.
    Jpn J Pharmacol; 2000 Oct 01; 84(2):213-20. PubMed ID: 11128045
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  • 30. Initial characterization of the major mouse cytochrome P450 enzymes involved in the reductive metabolism of the hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide (tirapazamine, SR 4233, WIN 59075).
    Riley RJ, Hemingway SA, Graham MA, Workman P.
    Biochem Pharmacol; 1993 Mar 09; 45(5):1065-77. PubMed ID: 8461036
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  • 31. Dehydrogenation of indoline by cytochrome P450 enzymes: a novel "aromatase" process.
    Sun H, Ehlhardt WJ, Kulanthaivel P, Lanza DL, Reilly CA, Yost GS.
    J Pharmacol Exp Ther; 2007 Aug 09; 322(2):843-51. PubMed ID: 17502430
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  • 32. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein.
    Shet MS, Faulkner KM, Holmans PL, Fisher CW, Estabrook RW.
    Arch Biochem Biophys; 1995 Apr 20; 318(2):314-21. PubMed ID: 7733659
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  • 33. The role of cytochrome P450 and cytochrome P450 reductase in the reductive bioactivation of the novel benzotriazine di-N-oxide hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233, WIN 59075) by mouse liver.
    Walton MI, Wolf CR, Workman P.
    Biochem Pharmacol; 1992 Jul 22; 44(2):251-9. PubMed ID: 1642640
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  • 34. Chiral sulfoxidation of albendazole by the flavin adenine dinucleotide-containing and cytochrome P450-dependent monooxygenases from rat liver microsomes.
    Moroni P, Buronfosse T, Longin-Sauvageon C, Delatour P, Benoit E.
    Drug Metab Dispos; 1995 Feb 22; 23(2):160-5. PubMed ID: 7736906
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  • 35. Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.
    Khojasteh-Bakht SC, Rossulek MI, Fouda HG, Prakash C.
    Xenobiotica; 2003 Dec 22; 33(12):1201-10. PubMed ID: 14742142
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  • 36. Identification of metabolic pathways involved in the biotransformation of tolperisone by human microsomal enzymes.
    Dalmadi B, Leibinger J, Szeberényi S, Borbás T, Farkas S, Szombathelyi Z, Tihanyi K.
    Drug Metab Dispos; 2003 May 22; 31(5):631-6. PubMed ID: 12695352
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  • 38. Selenoxidation by flavin-containing monooxygenases as a novel pathway for beta-elimination of selenocysteine Se-conjugates.
    Rooseboom M, Commandeur JN, Floor GC, Rettie AE, Vermeulen NP.
    Chem Res Toxicol; 2001 Jan 22; 14(1):127-34. PubMed ID: 11170516
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  • 39. The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.
    Mushiroda T, Douya R, Takahara E, Nagata O.
    Drug Metab Dispos; 2000 Oct 22; 28(10):1231-7. PubMed ID: 10997945
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  • 40. One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac.
    Boerma JS, Vermeulen NP, Commandeur JN.
    Chem Biol Interact; 2014 Jan 25; 207():32-40. PubMed ID: 24246759
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