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PUBMED FOR HANDHELDS

Journal Abstract Search

389 related items for PubMed ID: 17881660

  • 41.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 42. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
    Spracklin DK, Thummel KE, Kharasch ED.
    Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
    [Abstract] [Full Text] [Related]

  • 43. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A, Satoh H, Thomas PE, Bush E, Moore D.
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [Abstract] [Full Text] [Related]

  • 44. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
    Koenigs LL, Peter RM, Thompson SJ, Rettie AE, Trager WF.
    Drug Metab Dispos; 1997 Dec; 25(12):1407-15. PubMed ID: 9394031
    [Abstract] [Full Text] [Related]

  • 45. In vitro evaluation of the disposition of A novel cysteine protease inhibitor.
    Jacobsen W, Christians U, Benet LZ.
    Drug Metab Dispos; 2000 Nov; 28(11):1343-51. PubMed ID: 11038163
    [Abstract] [Full Text] [Related]

  • 46. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [Abstract] [Full Text] [Related]

  • 47. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S, Fujimaki Y, Yokoyama H, Okazaki O, Sudo K.
    Drug Metab Dispos; 2005 Nov; 33(11):1628-36. PubMed ID: 16049129
    [Abstract] [Full Text] [Related]

  • 48. Kinetics of ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems.
    Guengerich FP, Johnson WW.
    Biochemistry; 1997 Dec 02; 36(48):14741-50. PubMed ID: 9398194
    [Abstract] [Full Text] [Related]

  • 49.
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    [No Abstract] [Full Text] [Related]

  • 50. Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
    Bakken GV, Molden E, Knutsen K, Lunder N, Hermann M.
    Drug Metab Dispos; 2012 Sep 02; 40(9):1778-84. PubMed ID: 22688609
    [Abstract] [Full Text] [Related]

  • 51.
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  • 52. Identification of human liver cytochrome P450 isoforms involved in the in vitro metabolism of cyclobenzaprine.
    Wang RW, Liu L, Cheng H.
    Drug Metab Dispos; 1996 Jul 02; 24(7):786-91. PubMed ID: 8818577
    [Abstract] [Full Text] [Related]

  • 53. Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation.
    Indra R, Pompach P, Martínek V, Takácsová P, Vavrová K, Heger Z, Adam V, Eckschlager T, Kopečková K, Arlt VM, Stiborová M.
    Int J Mol Sci; 2019 Jul 10; 20(14):. PubMed ID: 31295928
    [Abstract] [Full Text] [Related]

  • 54. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.
    Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A.
    Drug Metab Dispos; 2010 Jan 10; 38(1):92-9. PubMed ID: 19812348
    [Abstract] [Full Text] [Related]

  • 55. Biotransformation of fluticasone: in vitro characterization.
    Pearce RE, Leeder JS, Kearns GL.
    Drug Metab Dispos; 2006 Jun 10; 34(6):1035-40. PubMed ID: 16565171
    [Abstract] [Full Text] [Related]

  • 56. Cytochrome P-450- and flavin-containing monooxygenase-catalyzed formation of the carcinogen N-hydroxy-2-aminofluorene and its covalent binding to nuclear DNA.
    Frederick CB, Mays JB, Ziegler DM, Guengerich FP, Kadlubar FF.
    Cancer Res; 1982 Jul 10; 42(7):2671-7. PubMed ID: 7083159
    [Abstract] [Full Text] [Related]

  • 57. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of dolasetron. Comparison with other indole-containing 5-HT3 antagonists.
    Sanwald P, David M, Dow J.
    Drug Metab Dispos; 1996 May 10; 24(5):602-9. PubMed ID: 8723743
    [Abstract] [Full Text] [Related]

  • 58. Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative. Similarity with the oxidation of arginine to citrulline and nitric oxide.
    Clement B, Schultze-Mosgau MH, Wohlers H.
    Biochem Pharmacol; 1993 Dec 14; 46(12):2249-67. PubMed ID: 8274159
    [Abstract] [Full Text] [Related]

  • 59. Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.
    Chiba M, Hensleigh M, Nishime JA, Balani SK, Lin JH.
    Drug Metab Dispos; 1996 Mar 14; 24(3):307-14. PubMed ID: 8820421
    [Abstract] [Full Text] [Related]

  • 60. In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker reaction for cytochrome P-4503A4 activity in human liver microsomes.
    Nielsen TL, Rasmussen BB, Flinois JP, Beaune P, Brosen K.
    J Pharmacol Exp Ther; 1999 Apr 14; 289(1):31-7. PubMed ID: 10086984
    [Abstract] [Full Text] [Related]

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