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140 related items for PubMed ID: 17883592

  • 1. Protease-activated receptor-induced Akt activation--regulation and possible function.
    Reséndiz JC, Kroll MH, Lassila R.
    J Thromb Haemost; 2007 Dec; 5(12):2484-93. PubMed ID: 17883592
    [Abstract] [Full Text] [Related]

  • 2. The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.
    Grenegård M, Vretenbrant-Oberg K, Nylander M, Désilets S, Lindström EG, Larsson A, Ramström I, Ramström S, Lindahl TL.
    J Biol Chem; 2008 Jul 04; 283(27):18493-504. PubMed ID: 18480058
    [Abstract] [Full Text] [Related]

  • 3. PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation.
    Holinstat M, Voss B, Bilodeau ML, McLaughlin JN, Cleator J, Hamm HE.
    J Biol Chem; 2006 Sep 08; 281(36):26665-74. PubMed ID: 16837456
    [Abstract] [Full Text] [Related]

  • 4. Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling.
    Kim S, Foster C, Lecchi A, Quinton TM, Prosser DM, Jin J, Cattaneo M, Kunapuli SP.
    Blood; 2002 May 15; 99(10):3629-36. PubMed ID: 11986217
    [Abstract] [Full Text] [Related]

  • 5. The roles and mechanisms of PAR4 and P2Y12/phosphatidylinositol 3-kinase pathway in maintaining thrombin-induced platelet aggregation.
    Wu CC, Wu SY, Liao CY, Teng CM, Wu YC, Kuo SC.
    Br J Pharmacol; 2010 Oct 15; 161(3):643-58. PubMed ID: 20880402
    [Abstract] [Full Text] [Related]

  • 6. Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.
    Campus F, Lova P, Bertoni A, Sinigaglia F, Balduini C, Torti M.
    J Biol Chem; 2005 Jul 01; 280(26):24386-95. PubMed ID: 15863506
    [Abstract] [Full Text] [Related]

  • 7. Akt activation in platelets depends on Gi signaling pathways.
    Kim S, Jin J, Kunapuli SP.
    J Biol Chem; 2004 Feb 06; 279(6):4186-95. PubMed ID: 14623889
    [Abstract] [Full Text] [Related]

  • 8. The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function.
    Gushiken FC, Hyojeong H, Pradhan S, Langlois KW, Alrehani N, Cruz MA, Rumbaut RE, Vijayan KV.
    PLoS One; 2009 Dec 15; 4(12):e8304. PubMed ID: 20016849
    [Abstract] [Full Text] [Related]

  • 9. Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: involvement of ERK2 and p38 and Ca2+ mobilization.
    Mazharian A, Roger S, Berrou E, Adam F, Kauskot A, Nurden P, Jandrot-Perrus M, Bryckaert M.
    J Biol Chem; 2007 Feb 23; 282(8):5478-87. PubMed ID: 17200114
    [Abstract] [Full Text] [Related]

  • 10. [Role of adenosine diphosphate in the course of thrombin signal transmission].
    Han Y, Lu XX, Wang ZY, Dai L, Shen WH, Wu DP, Ruan CG.
    Zhonghua Yi Xue Za Zhi; 2006 Dec 12; 86(46):3299-301. PubMed ID: 17313817
    [Abstract] [Full Text] [Related]

  • 11. Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen.
    Marjoram RJ, Voss B, Pan Y, Dickeson SK, Zutter MM, Hamm HE, Santoro SA.
    J Biol Chem; 2009 Dec 11; 284(50):34640-7. PubMed ID: 19815553
    [Abstract] [Full Text] [Related]

  • 12. PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis.
    Voss B, McLaughlin JN, Holinstat M, Zent R, Hamm HE.
    Mol Pharmacol; 2007 May 11; 71(5):1399-406. PubMed ID: 17303701
    [Abstract] [Full Text] [Related]

  • 13. Thrombin induces platelet activation in the absence of functional protease activated receptors 1 and 4 and glycoprotein Ib-IX-V.
    Lova P, Canobbio I, Guidetti GF, Balduini C, Torti M.
    Cell Signal; 2010 Nov 11; 22(11):1681-7. PubMed ID: 20600849
    [Abstract] [Full Text] [Related]

  • 14. Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF-κB signaling in human platelets.
    Chen WF, Lee JJ, Chang CC, Lin KH, Wang SH, Sheu JR.
    Haematologica; 2013 May 11; 98(5):793-801. PubMed ID: 23065519
    [Abstract] [Full Text] [Related]

  • 15. PAR4-Mediated PI3K/Akt and RhoA/ROCK Signaling Pathways Are Essential for Thrombin-Induced Morphological Changes in MEG-01 Cells.
    Heo Y, Jeon H, Namkung W.
    Int J Mol Sci; 2022 Jan 11; 23(2):. PubMed ID: 35054966
    [Abstract] [Full Text] [Related]

  • 16. Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets.
    Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S, Mulchandani M, Anderson K, Kauffenstein G, Rewcastle GW, Kendall J, Gachet C, Salem HH, Jackson SP.
    J Biol Chem; 2007 Sep 28; 282(39):28648-28658. PubMed ID: 17673465
    [Abstract] [Full Text] [Related]

  • 17. ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β.
    O'Brien KA, Gartner TK, Hay N, Du X.
    Arterioscler Thromb Vasc Biol; 2012 Sep 28; 32(9):2232-40. PubMed ID: 22814751
    [Abstract] [Full Text] [Related]

  • 18. Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets.
    Covic L, Gresser AL, Kuliopulos A.
    Biochemistry; 2000 May 09; 39(18):5458-67. PubMed ID: 10820018
    [Abstract] [Full Text] [Related]

  • 19. Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.
    Moore SF, Hunter RW, Hers I.
    J Thromb Haemost; 2014 May 09; 12(5):748-60. PubMed ID: 24612393
    [Abstract] [Full Text] [Related]

  • 20. Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.
    Shankar H, Murugappan S, Kim S, Jin J, Ding Z, Wickman K, Kunapuli SP.
    Blood; 2004 Sep 01; 104(5):1335-43. PubMed ID: 15142872
    [Abstract] [Full Text] [Related]

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