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Journal Abstract Search

384 related items for PubMed ID: 17900172

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  • 2. Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.
    Tevell A, Lennernäs H, Jönsson M, Norlin M, Lennernäs B, Bondesson U, Hedeland M.
    Drug Metab Dispos; 2006 Jun; 34(6):984-92. PubMed ID: 16540588
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  • 3. Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice.
    Lin MC, Wang EJ, Patten C, Lee MJ, Xiao F, Reuhl KR, Yang CS.
    J Biochem Toxicol; 1996 Jun; 11(1):11-20. PubMed ID: 8806047
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  • 4. Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone.
    Kostrubsky SE, Strom SC, Kalgutkar AS, Kulkarni S, Atherton J, Mireles R, Feng B, Kubik R, Hanson J, Urda E, Mutlib AE.
    Toxicol Sci; 2006 Apr; 90(2):451-9. PubMed ID: 16410371
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  • 9. Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity.
    Ohbuchi M, Miyata M, Nagai D, Shimada M, Yoshinari K, Yamazoe Y.
    Drug Metab Dispos; 2009 Jan; 37(1):97-105. PubMed ID: 18832480
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  • 10. Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients.
    Goda R, Nagai D, Akiyama Y, Nishikawa K, Ikemoto I, Aizawa Y, Nagata K, Yamazoe Y.
    Drug Metab Dispos; 2006 May; 34(5):828-35. PubMed ID: 16507648
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  • 11. Metabolism of the antiandrogenic drug (Flutamide) by human CYP1A2.
    Shet MS, McPhaul M, Fisher CW, Stallings NR, Estabrook RW.
    Drug Metab Dispos; 1997 Nov; 25(11):1298-303. PubMed ID: 9351907
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  • 12. Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.
    Mutlib AE, Goosen TC, Bauman JN, Williams JA, Kulkarni S, Kostrubsky S.
    Chem Res Toxicol; 2006 May; 19(5):701-9. PubMed ID: 16696573
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  • 14. Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophen-glutathione adducts.
    Manautou JE, Tveit A, Hoivik DJ, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1996 Sep; 140(1):30-8. PubMed ID: 8806867
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  • 15. Effect of acetaminophen administration to rats chronically exposed to depleted uranium.
    Guéguen Y, Grandcolas L, Baudelin C, Grison S, Tissandié E, Jourdain JR, Paquet F, Voisin P, Aigueperse J, Gourmelon P, Souidi M.
    Toxicology; 2007 Jan 05; 229(1-2):62-72. PubMed ID: 17126469
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  • 16. A Cytochrome P450-Independent Mechanism of Acetaminophen-Induced Injury in Cultured Mouse Hepatocytes.
    Miyakawa K, Albee R, Letzig LG, Lehner AF, Scott MA, Buchweitz JP, James LP, Ganey PE, Roth RA.
    J Pharmacol Exp Ther; 2015 Aug 05; 354(2):230-7. PubMed ID: 26065700
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  • 17. [Sex-difference on flutamide metabolism in rat liver microsomal cytochrome P450 1A2].
    Wang HX, Li D, Xu CJ, Liu X.
    Yao Xue Xue Bao; 2002 Aug 05; 37(8):608-10. PubMed ID: 12567773
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  • 18. Metabolism and hepatic toxicity of flutamide in cytochrome P450 1A2 knockout SV129 mice.
    Matsuzaki Y, Nagai D, Ichimura E, Goda R, Tomura A, Doi M, Nishikawa K.
    J Gastroenterol; 2006 Mar 05; 41(3):231-9. PubMed ID: 16699857
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  • 19. Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase.
    Wen B, Coe KJ, Rademacher P, Fitch WL, Monshouwer M, Nelson SD.
    Chem Res Toxicol; 2008 Dec 05; 21(12):2393-406. PubMed ID: 19548358
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  • 20. Cytotoxicity of flutamide and 2-hydroxyflutamide and their effects on CYP1A2 mRNA in primary rat hepatocytes.
    Wang HX, Ma XC, Deng QL, Li D.
    Acta Pharmacol Sin; 2002 Jun 05; 23(6):562-6. PubMed ID: 12060533
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