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Journal Abstract Search

347 related items for PubMed ID: 17902053

  • 1. Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.
    Puig T, Vázquez-Martín A, Relat J, Pétriz J, Menéndez JA, Porta R, Casals G, Marrero PF, Haro D, Brunet J, Colomer R.
    Breast Cancer Res Treat; 2008 Jun; 109(3):471-9. PubMed ID: 17902053
    [Abstract] [Full Text] [Related]

  • 2. Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals.
    Puig T, Relat J, Marrero PF, Haro D, Brunet J, Colomer R.
    Anticancer Res; 2008 Jun; 28(6A):3671-6. PubMed ID: 19189648
    [Abstract] [Full Text] [Related]

  • 3. Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.
    Zhou W, Simpson PJ, McFadden JM, Townsend CA, Medghalchi SM, Vadlamudi A, Pinn ML, Ronnett GV, Kuhajda FP.
    Cancer Res; 2003 Nov 01; 63(21):7330-7. PubMed ID: 14612531
    [Abstract] [Full Text] [Related]

  • 4. Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.
    Relat J, Blancafort A, Oliveras G, Cufí S, Haro D, Marrero PF, Puig T.
    BMC Cancer; 2012 Jul 06; 12():280. PubMed ID: 22769244
    [Abstract] [Full Text] [Related]

  • 5. RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells.
    Menendez JA, Lupu R.
    Int J Mol Med; 2005 Jan 06; 15(1):33-40. PubMed ID: 15583825
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.
    Menendez JA, Colomer R, Lupu R.
    Med Hypotheses; 2005 Jan 06; 64(2):337-41. PubMed ID: 15607568
    [Abstract] [Full Text] [Related]

  • 7. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
    Menendez JA, Ropero S, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Jun 06; 24(6):1369-83. PubMed ID: 15138577
    [Abstract] [Full Text] [Related]

  • 8. Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
    Bentebibel A, Sebastián D, Herrero L, López-Viñas E, Serra D, Asins G, Gómez-Puertas P, Hegardt FG.
    Biochemistry; 2006 Apr 11; 45(14):4339-50. PubMed ID: 16584169
    [Abstract] [Full Text] [Related]

  • 9. Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling.
    Pan MH, Lin CC, Lin JK, Chen WJ.
    J Agric Food Chem; 2007 Jun 27; 55(13):5030-7. PubMed ID: 17539658
    [Abstract] [Full Text] [Related]

  • 10. Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells.
    Vazquez-Martin A, Colomer R, Brunet J, Menendez JA.
    Int J Oncol; 2007 Oct 27; 31(4):769-76. PubMed ID: 17786307
    [Abstract] [Full Text] [Related]

  • 11. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
    Thupari JN, Pinn ML, Kuhajda FP.
    Biochem Biophys Res Commun; 2001 Jul 13; 285(2):217-23. PubMed ID: 11444828
    [Abstract] [Full Text] [Related]

  • 12. Fatty acid metabolism as a target for obesity treatment.
    Ronnett GV, Kim EK, Landree LE, Tu Y.
    Physiol Behav; 2005 May 19; 85(1):25-35. PubMed ID: 15878185
    [Abstract] [Full Text] [Related]

  • 13. The connections between C75 and obesity drug-target pathways.
    Kuhajda FP, Landree LE, Ronnett GV.
    Trends Pharmacol Sci; 2005 Nov 19; 26(11):541-4. PubMed ID: 16169094
    [Abstract] [Full Text] [Related]

  • 14. C75 [4-methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylic acid] activates carnitine palmitoyltransferase-1 in isolated mitochondria and intact cells without displacement of bound malonyl CoA.
    Yang N, Kays JS, Skillman TR, Burris L, Seng TW, Hammond C.
    J Pharmacol Exp Ther; 2005 Jan 19; 312(1):127-33. PubMed ID: 15356215
    [Abstract] [Full Text] [Related]

  • 15. Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase.
    Wang X, Tian W.
    Biochem Biophys Res Commun; 2001 Nov 16; 288(5):1200-6. PubMed ID: 11700039
    [Abstract] [Full Text] [Related]

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  • 17. Epigallocatechin-3 gallate induces growth inhibition and apoptosis in human breast cancer cells through survivin suppression.
    Tang Y, Zhao DY, Elliott S, Zhao W, Curiel TJ, Beckman BS, Burow ME.
    Int J Oncol; 2007 Oct 16; 31(4):705-11. PubMed ID: 17786300
    [Abstract] [Full Text] [Related]

  • 18. C75 activates malonyl-CoA sensitive and insensitive components of the CPT system.
    Nicot C, Napal L, Relat J, González S, Llebaria A, Woldegiorgis G, Marrero PF, Haro D.
    Biochem Biophys Res Commun; 2004 Dec 17; 325(3):660-4. PubMed ID: 15541339
    [Abstract] [Full Text] [Related]

  • 19. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity.
    Thupari JN, Landree LE, Ronnett GV, Kuhajda FP.
    Proc Natl Acad Sci U S A; 2002 Jul 09; 99(14):9498-502. PubMed ID: 12060712
    [Abstract] [Full Text] [Related]

  • 20. Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.
    Menendez JA, Vazquez-Martin A, Oliveras-Ferraros C, Garcia-Villalba R, Carrasco-Pancorbo A, Fernandez-Gutierrez A, Segura-Carretero A.
    Int J Mol Med; 2008 Oct 09; 22(4):433-9. PubMed ID: 18813848
    [Abstract] [Full Text] [Related]

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